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Preoperative embolization is necessary for large-volume carotid body tumor (≥ 6670 mm3) resection

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Abstract

Background

To investigate the impact of preoperative embolization (p-TAE) on CBT surgical resection and explore the optimal tumor volume for p-TAE of CBT resection.

Methods

This retrospective study reviewed 139 surgically excised CBTs. According to Shamblin classification, tumor volumes, and whether to carry out the p-TAE, the patients were classified into different groups. The demographic, clinical features, and the intraoperative and post-operative information about the patients were retrieved and analyzed from the patient records.

Results

A total of 139 CBTs was excised in 130 patients. According to the results of subgroup analysis, there were no significant differences in surgical time, blood loss, adverse events (AEs), and the revascularization when compared with non-embolization group (NEG) for type I, II, III, respectively (all p > 0.05) except for the surgical time in type I (p < 0.05). Then the X-tile program was employed and determine the cutoff point (tumor volume = 6670 mm3) for tumor volumes and blood loss. The average tumor volume was (29,782.37 vs. 31,345.10 mm3, p = 0.65) for embolization group (EG) and NEG. The mean surgical time (208.86 vs. 264.67 min, p > 0.05) and intraoperative blood loss (252.78 vs. 430.00 mL, p < 0.05) were less, and the incidence of revascularization required (35.56 vs. 52.38%, p > 0.05) and total complications (27.78 vs. 57.14%, p < 0.05) were lower in EG when compared with NEG (tumor volume ≥ 6670 mm3). However, the results were not statistically significant when the tumor size was less than 6670 mm3. No surgery-related mortality was observed during the follow-up.

Conclusions

Preoperative selective embolization of CBT is an effective and safe adjunct for surgical resection, especially for Shamblin class II and III tumors (≥ 6670 mm3).

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Funding

This work is supported by Project of Guangzhou Municipal Health Bureau, China (20231A011006).

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Authors and Affiliations

  1. The First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong, China

    Li Nan

  2. Department of Interventional Radiology, Guangzhou First People’s Hospital, Guangzhou, 510180, China

    Li Nan & Yang Ruimeng

  3. Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, Guangdong, China

    Li Nan & Huang Yonghui

  4. Department of Vascular Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, Guangdong, China

    Chang Guangqi

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  1. Li Nan
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  2. Yang Ruimeng
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  3. Chang Guangqi
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  4. Huang Yonghui
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Correspondence to Chang Guangqi or Huang Yonghui.

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Nan, L., Ruimeng, Y., Guangqi, C. et al. Preoperative embolization is necessary for large-volume carotid body tumor (≥ 6670 mm3) resection. Eur Arch Otorhinolaryngol 280, 4177–4183 (2023). https://doi.org/10.1007/s00405-023-07990-2

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  • DOI: https://doi.org/10.1007/s00405-023-07990-2

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