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Bacteriology of acute rhinosinusitis in nasopharyngeal carcinoma survivors: a result of maxillary sinus punctures

  • Rhinology
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Abstract

Rhinosinusitis is a common complication in patients with nasopharyngeal carcinoma (NPC) who receive radiotherapy. An impaired mucociliary clearance due to this treatment may be the major cause of rhinosinusitis in these irradiated patients. The relative frequency with which various pathogens cause rhinosinusitis in these patients is unknown. This study investigates the bacteriology of acute rhinosinusitis in irradiated NPC patients by maxillary sinus puncture. From October 2001 through July 2006, 20 irradiated NPC patients with radiograph-proven acute maxillary sinusitis received maxillary sinus punctures. Aspirate contents of the sinuses were collected for aerobic and anaerobic cultivation. A total sampling of 26 sides was performed in the 20 patients. The culture rate was 85%. Frequently identified aerobes and facultative anaerobes included alpha-hemolytic streptococcus (n = 8), Staphylococcus aureus (n = 5) and Pseudomonas aeruginosa (n = 3). Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, however, are far less common. This may provide important information about the antibiotic therapy in irradiated NPC patients with acute rhinosinusitis.

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Authors and Affiliations

  1. Department of Otolaryngology, Chung Shan Medical University Hospital, Taichung, Taiwan

    Chung-Han Hsin, Chien-Han Tsao & Mao-Chang Su

  2. Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan

    Chung-Han Hsin & Ming-Chih Chou

  3. Department of Otolaryngology, National Taiwan University Hospital, 1 Chang-Teh Street, Taipei, 10016, Taiwan

    Chia-Ming Liu

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  1. Chung-Han Hsin
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  2. Chien-Han Tsao
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  3. Mao-Chang Su
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  4. Ming-Chih Chou
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  5. Chia-Ming Liu
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Correspondence to Chia-Ming Liu.

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Hsin, CH., Tsao, CH., Su, MC. et al. Bacteriology of acute rhinosinusitis in nasopharyngeal carcinoma survivors: a result of maxillary sinus punctures. Eur Arch Otorhinolaryngol 264, 1157–1162 (2007). https://doi.org/10.1007/s00405-007-0334-9

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  • DOI: https://doi.org/10.1007/s00405-007-0334-9

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