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Amniotic fluid-derived mesenchymal stem cells: characteristics and therapeutic applications

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Abstract

Purpose

Amniotic fluid mesenchymal stem cells (AF-MSCs) are promising candidates for cell-based therapy. This review presents a comprehensive overview of the features and therapeutic applications of these cells.

Methods

This is a literature review combined with experience of practice.

Conclusion

Although the long-term risks of AF-MSCs require further investigation, these cells are increasing in popularity in the fields of regenerative medicine and targeting therapy because of their unique properties.

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Acknowledgments

We thank Dr. Jian-Hua Zhou for the thoughtful comments on and refinements to this review. The authors’ work in this area is supported by grants from the Major State Basic Research Development Program of China (2012CB526705) and Harbin Medical University. The authors’ work in this area was performed in the National Key Laboratory of the Harbin Veterinary Research Institute.

Conflict of interest

The authors’ work in this area is supported by grants from the Major State Basic Research Development Program of China (2012CB526705) and Harbin Medical University.

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Authors and Affiliations

  1. Harbin Medical University, Harbin, 150001, Heilongjiang, China

    Jun Zhou, Dejun Wang & Tian Liang

  2. The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China

    Qiuyan Guo & Guangmei Zhang

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  1. Jun Zhou
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Correspondence to Guangmei Zhang.

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Zhou, J., Wang, D., Liang, T. et al. Amniotic fluid-derived mesenchymal stem cells: characteristics and therapeutic applications. Arch Gynecol Obstet 290, 223–231 (2014). https://doi.org/10.1007/s00404-014-3231-7

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