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Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An experimental study

  • Orthopaedic Surgery
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Objective

In the current study, it was aimed to investigate the temperature change in the cavity wall and pathologic necrosis occurred during cauterization, which was applied at different voltages and time intervals.

Materials and methods

The right tibias of 32 male rabbits were used. Three 2-mm-diameter holes were created on the cortical surface of the tibia using a hand-held drill. Using an electrocautery device, 55 mV was applied for 3 and 5 s and 65 mV was applied for 3 and 5 s. Maximum temperatures at 3 and 6 mm distance from the application site were measured. Biopsy specimens obtained at 3 and 6 mm distance from the application site were evaluated microscopically for bone cell viability and periosteal necrosis.

Results

Thirty-two rabbits were divided into four groups. In all groups, periosteal bone cells located at the region, extending from the application site to 3 mm distance, died. In this region, application of 55 mV for 3 s caused peripheral necrosis. There were significant differences between the four groups in terms of maximum temperatures measured at 3 mm distance from the application site (p = 0.027). On the other hand, no significant differences were noted between the four groups in terms of maximum temperatures measured at 6 mm distance from the application site (p > 0.05).

Conclusions

Cauterization of the cavity wall in the spray mode at 55 mV for 3 s after tumor resection caused necrosis in the cavity wall, extending from the application site to 3 mm distance.

Level of evidence: Experimental animal study, Level II.

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Acknowledgments

This study was funded by BAP (Ankara University Scientific Research Center, a Department of Ankara University). BAP payed for project expenses nearly 23000 $. None of the authors got payment or salary for the project.

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Authors and Affiliations

  1. Department of Orthopedics and Traumatology, Afyonkarahisar Suhut Public Hospital Medicine, Afyonkarahisar, Turkey

    Murat Aydin

  2. Department of Orthopedics and Traumatology, Faculty of Medicine, Ankara University, Ankara, Turkey

    Kerem Basarir, Mehmet Armangil, Huseyin Yusuf Yildiz & Yener Saglik

  3. Department of Surgery, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey

    Hasan Bilgili

  4. Department of Pathology, Faculty of Veterinary Medicine, Harran University, Urfa, Turkey

    Nihat Yumusak

Authors
  1. Murat Aydin
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  2. Kerem Basarir
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  3. Mehmet Armangil
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  4. Huseyin Yusuf Yildiz
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  5. Yener Saglik
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  6. Hasan Bilgili
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Correspondence to Murat Aydin.

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Aydin, M., Basarir, K., Armangil, M. et al. Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An experimental study. Arch Orthop Trauma Surg 135, 1071–1076 (2015). https://doi.org/10.1007/s00402-015-2262-2

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  • DOI: https://doi.org/10.1007/s00402-015-2262-2

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