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Robotic colorectal resection in combination with a multimodal enhanced recovery program - results of the first 100 cases

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A Correction to this article was published on 26 March 2024

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Abstract

Purpose

In Germany, colorectal robot-assisted surgery (RAS) has found its way and is currently used as primary technique in colorectal resections at our clinic. We investigated whether RAS can be extensively combined with enhanced recovery after surgery (ERAS®) in a large prospective patient group.

Methods

Using the DaVinci Xi surgical robot, all colorectal RAS from 09/2020 to 01/2022 were incorporated into our ERAS® program. Perioperative data were prospectively recorded using a data documentation system. The extent of resection, duration of the operation, intraoperative blood loss, conversion rate, and postoperative short-term results were analyzed. We documented the postoperative duration of Intermediate Care Unit (IMC) stay and major and minor complications according to the Clavien–Dindo classification, anastomotic leak rate, reoperation rate, hospital-stay length, and ERAS® guideline adherence.

Results

One hundred patients (65 colon and 35 rectal resections) were included (median age: 69 years). The median durations of surgery were 167 min (colon resection) and 246 min (rectal resection). Postoperatively, four patients were IMC-treated (median stay: 1 day). In 92.5% of the colon and 88.6% of the rectum resections, no or minor complications occurred postoperatively. The anastomotic leak rate was 3.1% in colon and 5.7% in rectal resection. The reoperation rate was 7.7% (colon resection) and 11.4% (rectal resection). The hospital stay length was 5 days (colon resection) and 6.5 days (rectal resection). The ERAS® guideline adherence rate was 88% (colon resection) and 82.6% (rectal resection).

Conclusion

Patient perioperative therapy per the multimodal ERAS® concept is possible without any problems in colorectal RAS, leading to low morbidity and short hospital stays.

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References

  1. Schwenk W (2009) Fast Track Rehabilitation in der Viszeralchirurgie. Chirurg 80:690–701

    Article  CAS  PubMed  Google Scholar 

  2. Kehlet H, Wilmore DW (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606–617

    Article  CAS  PubMed  Google Scholar 

  3. Gustafsson UO, Scott MJ, Hubner M et al (2019) Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018. World J Surg 43:659–695. https://doi.org/10.1007/s00268-018-4844-y

    Article  CAS  PubMed  Google Scholar 

  4. Lacy AM, Delgado S, Castells A et al (2008) The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer. Ann Surg 248:1–7

    Article  PubMed  Google Scholar 

  5. Bonjer HJ, Deijen CL, Abis GA et al (2015) A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med 372:1324–1332

    Article  CAS  PubMed  Google Scholar 

  6. Watt DG, McSorley ST, Horgan PG et al (2015) Enhanced recovery after surgery: which components, if any, impact on the systemic inflammatory response following colorectal surgery?: a systematic review. Medicine (Baltimore) 94:e1286

    Article  CAS  PubMed  Google Scholar 

  7. Gómez Ruiz M, Lainez Escribano M, Cagigas Fernández C, Cristobal Poch L, Santarrufina MS (2020) Robotic surgery for colorectal cancer. Ann Gastroenterol Surg 4(6):646–651. https://doi.org/10.1002/ags3.12401. (PMID: 33319154; PMCID: PMC7726686)

    Article  PubMed  PubMed Central  Google Scholar 

  8. Koch F, Green M, Dietrich M, Pontau F, Moikow L, Ulmer S, Dietrich N, Ritz JP (2022) Achtzehn Monate als zertifiziertes ERAS®-Zentrum für kolorektale Resektionen: Lessons learned und Ergebnisse der ersten 261 Patienten [First 18 months as certified ERAS® center for colorectal cancer : Lessons learned and results of the first 261 patients]. Chirurgie (Heidelb) 93(7):687–693. German. https://doi.org/10.1007/s00104-021-01567-7. (Epub 2022 Feb 8. PMID: 35137247)

  9. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213. https://doi.org/10.1097/01.sla.0000133083.54934.ae.PMID:15273542;PMCID:PMC1360123

    Article  PubMed  PubMed Central  Google Scholar 

  10. Colorectal resections - proportion of the laparoscopic colorectal resections at all Helios clinics in Germany. Annual Data of the Helios group 2020

  11. StuDoQ Qualitätsreport kolorektales Karzinom (2021)

  12. de Neree Tot Babberich MPM, van Groningen JT, Dekker E, et al (2018) Laparoscopic conversion in colorectal cancer surgery; is there any improvement over time at a population level? Surg Endosc 32:3234–3246

    Article  PubMed  Google Scholar 

  13. Leitlinienprogramm Onkologie (2019) (Deutsche Krebsgesellschaft, Deutsche Krebshilfe, AWMF): S3-Leitlinie Kolorektales Karzinom, Langversion 2.1. AWMF Registrierungsnummer: 021/007OL. http://www.leitlinienprogramm-onkologie.de/leitlinien/kolorektales-karzinom/. (abgerufen am: 25.06.2022)

  14. Parascandola SA, Horsey ML, Hota S, Paull JO, Graham A, Pudalov N, Smith S, Amdur R, Obias V (2021) The robotic colorectal experience: an outcomes and learning curve analysis of 502 patients. Colorectal Dis 23(1):226–236. https://doi.org/10.1111/codi.15398. (Epub 2020 Nov 4 PMID: 33048409)

    Article  PubMed  Google Scholar 

  15. Katz SC, Shia J, Liau KH, Gonen M, Ruo L, Jarnagin WR, Fong Y, D’Angelica MI, Blumgart LH, Dematteo RP (2009) Operative blood loss independently predicts recurrence and survival after resection of hepatocellular carcinoma. Ann Surg 249(4):617–623. https://doi.org/10.1097/SLA.0b013e31819ed22f. (PMID: 19300227)

    Article  PubMed  Google Scholar 

  16. Charalambides M, Mavrou A, Jennings T et al (2022) A systematic review of the literature assessing operative blood loss and postoperative outcomes after colorectal surgery. Int J Colorectal Dis 37:47–69. https://doi.org/10.1007/s00384-021-04015-4

  17. Okamura R, Hida K, Hasegawa S, Sakai Y, Hamada M, Yasui M, Hinoi T, Watanabe M, Japan Society of Laparoscopic Colorectal Surgery (2016) Impact of intraoperative blood loss on morbidity and survival after radical surgery for colorectal cancer patients aged 80 years or older. Int J Colorectal Dis 31(2):327–34. https://doi.org/10.1007/s00384-015-2405-5. (Epub 2015 Sep 28. PMID: 26412248)

  18. Poon JTC, Law WL, Chow LCY et al (2011) Outcome of Laparoscopic Resection for Colorectal Cancer in Patients with High Operative Risk. Ann Surg Oncol 18:1884–1890. https://doi.org/10.1245/s10434-010-1530-1

    Article  PubMed  Google Scholar 

  19. Saleh A, Ihedioha U, Babu B, Evans J, Kang P (2016) Is estimated intra-operative blood loss a reliable predictor of surgical outcomes in laparoscopic colorectal cancer surgery? Scott Med J 61(3):167–170. https://doi.org/10.1177/0036933015597174. (Epub 2015 Jul 24 PMID: 26209612)

    Article  CAS  PubMed  Google Scholar 

  20. Celik S, Yılmaz EM (2018) Effects of Laparoscopic and Conventional Methods on Lung Functions in Colorectal Surgery. Med Sci Monit 17(24):3244–3248. https://doi.org/10.12659/MSM.906973.PMID:29770791;PMCID:PMC5985708

    Article  Google Scholar 

  21. Ahmed EA, Montalti R, Nicolini D, Vincenzi P, Coletta M, Vecchi A, Mocchegiani F, Vivarelli M. Fast track program in liver resection: a PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore). 2016 Jul;95(28):e4154. https://doi.org/10.1097/MD.0000000000004154. (PMID: 27428206; PMCID: PMC4956800)

  22. Gramigni E, Bracco D, Carli F (2013) Epidural analgesia and postoperative orthostatic haemodynamic changes: observational study. Eur J Anaesthesiol 30(7):398–404. https://doi.org/10.1097/EJA.0b013e32835b162c. (PMID: 23435278)

    Article  CAS  PubMed  Google Scholar 

  23. Hanna MH, Jafari MD, Jafari F, Phelan MJ, Rinehart J, Sun C, Carmichael JC, Mills SD, Stamos MJ, Pigazzi A (2017) Randomized Clinical Trial of Epidural Compared with Conventional Analgesia after Minimally Invasive Colorectal Surgery. J Am Coll Surg 225(5):622–630. https://doi.org/10.1016/j.jamcollsurg.2017.07.1063. (Epub 2017 Aug 3 PMID: 28782603)

    Article  PubMed  Google Scholar 

  24. Jahresbericht Darm (2021) (Deutsche Krebsgesellschaft): Auditjahr 2020 / Kennzahlenjahr 2019, Qualitätsindikatoren Darmkrebs 2021 [abgerufen am: 25.06.2022]

  25. Rouanet P, Mermoud A, Jarlier M, Bouazza N, Laine A, Mathieu Daudé H (2020) Combined robotic approach and enhanced recovery after surgery pathway for optimization of costs in patients undergoing proctectomy. BJS Open 4(3):516–523. https://doi.org/10.1002/bjs5.50281. (Epub 2020 Apr 30. PMID: 32352227; PMCID: PMC7260409)

  26. Ni X, Jia D, Chen Y, Wang L, Suo J (2019) Is the Enhanced Recovery After Surgery (ERAS) Program Effective and Safe in Laparoscopic Colorectal Cancer Surgery? A Meta-Analysis of Randomized Controlled Trials. J Gastrointest Surg 23(7):1502–1512. https://doi.org/10.1007/s11605-019-04170-8. (Epub 2019 Mar 11 PMID: 30859422)

    Article  PubMed  Google Scholar 

  27. Wei IH, Pappou EP, Smith JJ, Widmar M, Nash GM, Weiser MR, Paty PB, Guillem JG, Afonso A, Garcia-Aguilar J (2020) Monitoring an Ongoing Enhanced Recovery After Surgery (ERAS) Program: Adherence Improves Clinical Outcomes in a Comparison of Three Thousand Colorectal Cases. Clin Surg 5:2909. (Epub 2020 Aug 10. PMID: 33163851; PMCID: PMC7643765)

  28. Catarci M, Benedetti M, Maurizi A, Spinelli F, Bernacconi T, Guercioni G, Campagnacci R (2021) ERAS pathway in colorectal surgery: structured implementation program and high adherence for improved outcomes. Updates Surg 73(1):123–137. https://doi.org/10.1007/s13304-020-00885-5. (Epub 2020 Oct 22 PMID: 33094366)

    Article  PubMed  Google Scholar 

  29. Marusch F, Koch A, Schmidt U, Zippel R, Lehmann M, Czarnetzki HD et al (2001) Effect of caseload on the short-term outcome of colon surgery: results of a multicenter study. Int J Colorectal Dis 16(6):362–369

    Article  CAS  PubMed  Google Scholar 

  30. Marusch F, Koch A, Schmidt U et al (2002) Prospektive Multizenterstudien „Kolon-/ Rektumkarzinome“ als flächendeckende chirurgische Qualitätssicherung. Chirurg 73:138–146

    Article  CAS  PubMed  Google Scholar 

  31. Marusch F, Koch A, Schmidt U et al (2002) Welche Faktoren beeinflussen die postoperative Letalität beim kolorektalen Karzinom? Zentralbl Chir 127:614–621

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

Authors

Contributions

All the authors contributed to the conception and design of the study. Material preparation, data collection and analysis were performed by Mohamad El-Ahmar, Melanie Dietrich, Martina Green, Lutz Moikow and Franziska Koch. Matthias Ristig and Jörg-Peter Ritz set the target parameters and monitored the analysis. Mohamad El-Ahmar wrote the manuscript. Jörg-Peter Ritz commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to M. El-Ahmar.

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Patients’ informed consent to participate in the study has been obtained.

Research involving human participants

Ethical approval was waived by the local Ethics Committee of the medical faculty of the University of Rostock on January 10, 2019, in view of the prospective nature of the study and all procedures having been performed as part of routine care.

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There are no relevant financial or non-financial competing interests to report.

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El-Ahmar, M., Peters, F., Green, M. et al. Robotic colorectal resection in combination with a multimodal enhanced recovery program - results of the first 100 cases. Int J Colorectal Dis 38, 95 (2023). https://doi.org/10.1007/s00384-023-04380-2

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