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Mesenchymal hamartoma of the liver: is biopsy always necessary?

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References

  1. Dehner LP, Ewing SL, Sumner HW (1975) Infantile mesenchymal hamartoma of the liver: histological and ultrastructural observations. Arch Pathol 99:379–382

    PubMed  CAS  Google Scholar 

  2. Murthi GVS, Paterson L, Azmy A (2003) Chromosomal translocation in mesenchymal hamartoma of the liver: what is its significance? J Pediatr Surg 38(10):1543–1545

    Article  PubMed  CAS  Google Scholar 

  3. Lennington WJ, Gray GF Jr, Page DL (1993) Mesenchymal hamartoma of the liver: a regional ischaemic lesion of a sequestered lobe. Am J Dis Child 147:193–196

    PubMed  CAS  Google Scholar 

  4. Stanley RJ, Dehner LP, Hesker AE (1973) Primary malignant mesenchymal tumors (mesenchymoma) of the liver in childhood: an angiographic–pathologic study of three cases. Cancer 32:973–984

    Article  PubMed  CAS  Google Scholar 

  5. Goodman ZD (1984) Histologic diagnosis of hepatic tumours. Ann Clin Lab Sci 14(3):169–178

    PubMed  CAS  Google Scholar 

  6. Stocker JT, Ishak KG (1978) Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. Cancer 42:336–348

    Article  PubMed  CAS  Google Scholar 

  7. Leuschner I, Schmidt D, Harms D (1990a) Undifferentiated sarcoma of the liver in childhood: morphology, flow cytometry and literature review. Human Pathol 21(1):68–76

    Article  CAS  Google Scholar 

  8. Ramanujam TM, Ramesh JC, Goh DW, Wong KT, Ariffin WA, Kumar G, Taib NA (1999) Malignant transformation of mesenchymal hamartoma of the liver: case report and review of the literature. J Pediatr Surg 34(11):1684–1686

    Article  PubMed  CAS  Google Scholar 

  9. Otal TM, Hendricks JB, Pharis P, Donnelly WH (1994) Mesenchymal hamartoma of the liver: DNA flow cytometric analysis of eight cases. Cancer 74(4):1237–1242

    Article  PubMed  CAS  Google Scholar 

  10. Lauwers GY, Grant LD, Donnelly WH, Meloni AM, Foss R, Sanberg AA, Langham MR Jr (1997) Hepatic undifferentiated (embryonal) sarcoma arising in a mesenchymal hamartoma. Am J Surg Pathol 21(10):1248–1254

    Article  PubMed  CAS  Google Scholar 

  11. De Chadarevian JP, Pawel BR, Faerber EN, Weintraub WH (1994) Undifferentiated (embryonal) sarcoma arising in conjunction with mesenchymal hamartoma of the liver. Mod Pathol 7:490–493

    PubMed  Google Scholar 

  12. Gallivan MVE, Lack EE, Chun B, Ishak KG (1983) Undifferentiated (“embryonal”) sarcoma of the liver: ultrastructure of a case presenting as a primary intracardiac tumour. Pediatr Pathol 1:291–300

    Article  PubMed  CAS  Google Scholar 

  13. O`Sullivan MJ, Swanson PE, Knoll J, Taboada EM, Dehner LP (2001) Undifferentiated embryonal sarcoma with unusual features arising within a mesenchymal hamartoma of the liver: report of a case and review of the literature. Pediatr Dev Pathol 4:482–489

    Article  CAS  Google Scholar 

  14. Mascarello JT, Krous HF (1992) Second report of a translocation involving 19q13.4 in a mesenchymal hamartoma of the liver. Cancer Genet Cytogenet 58:141–142

    Article  PubMed  CAS  Google Scholar 

  15. Lack EE (1986) Mesenchymal hamartoma of the liver: a clinical and pathological study of nine cases. Am J Pediatr Hematol Oncol 8(2):91–98

    PubMed  CAS  Google Scholar 

  16. Corbally MT, Spitz L (1992) Malignant potential of mesenchymal hamartoma: an unrecognised risk. Pediatr Surg Int 7:321–322

    Article  Google Scholar 

  17. Barnhart DC, Hirschl RB, Garver KA, Geiger JD, Harmon CM, Coran AG (1997) Conservative management of mesenchymal hamartoma of the liver. J Pediatr Surg 32(10):1495–1498

    Article  PubMed  CAS  Google Scholar 

  18. Leary DL, Weiskittel DA, Blane CE, Coran AG (1989) Follow-up imaging of benign pediatric liver tumours. Pediatr Radiol 19:234–236

    Article  PubMed  CAS  Google Scholar 

  19. Aoyama C, Hachitanda Y, Sato JK, Said JW, Shimada H (1991) Undifferentiated (embryonal) sarcoma of the liver: a tumour of uncertain histogenesis showing divergent differentiation. Am J Surg Pathol 15(7):615–624

    Article  PubMed  CAS  Google Scholar 

  20. Parham DM, Kelly DR, Donnelly WH, Douglass EC (1991) Immunohistochemical and ultastructural spectrum of hepatic sarcomas of childhood: evidence for a common histogenesis. Mod Pathol 4(5):648–653

    PubMed  CAS  Google Scholar 

  21. Steiner M, Bostrum B, Leonard AS, Dehner LP (1989) Undifferentiated (embryonal) sarcoma of the liver: a clinicopathological study of a survivor treated with combined technique therapy. Cancer 64:1318–1322

    Article  PubMed  CAS  Google Scholar 

  22. Keating S, Taylor GP (1985) Undifferentiated (embryonal) sarcoma of the liver: ultrastructural and immunohistochemical similarities with malignant fibrous histiocytoma. Human Pathol 16:693–699

    Article  CAS  Google Scholar 

  23. Sawyer JR, Roloson GJ, Bell JM, Thomas JR, Teo C, Chadduck WM (1996) Telomeric associations in the progression of chromosome aberrations in pediatric solid tumours. Cancer Genet Cytogenet 90:1–13

    Article  PubMed  CAS  Google Scholar 

  24. Ilizko M, Czauderna P, Babinska M, Stoba C, Roszkiewicz A, Limon J (1998) Cytogenetic findings in an embryonal sarcoma of the liver. Cancer Genet Cytogenet 102:142–144

    Article  Google Scholar 

  25. Leuschner I, Schmidt D, Harms D (1990b) Undifferentiated sarcoma of the liver in childhood: morphology, flow cytometry and literature review. Hum Pathol 21:68–76

    Article  CAS  Google Scholar 

  26. Chou P, Mangkornkanok M, Gonzalez-Crussi F (1990) Undifferentiated (embryonal) sarcoma of the liver: ultrastructure, immunohistochemistry, and DNA ploidy analysis of two cases. Pediatr Pathol 10:549–562

    Article  PubMed  CAS  Google Scholar 

  27. Bove KE, Blough RI, Soukup S (1998) Third report of t(19q)(13.4) in mesenchymal hamartoma of the liver with comments on link to embryonal sarcoma. Pediatr Dev Pathol 1:438–442

    Article  PubMed  CAS  Google Scholar 

  28. Speleman F, De Telder V, De Potter KR, Dal Cin P, Van Daele S, Benoit Y, Leroy JG, Van Den Berghe H (1989) Cytogenetic analysis of a mesenchymal hamartoma of the liver. Cancer Genet Cytogenet 40:29–32

    Article  PubMed  CAS  Google Scholar 

  29. Rakheja D, Margraf LR, Tomlinson GE, Schneider NR (2004) Hepatic mesenchymal hamartoma with translocation involving chromosome band 19q13.4: a recurrent abnormality. Cancer Genet Cytogenet 153:60–63

    Article  PubMed  CAS  Google Scholar 

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  1. Department of Paediatric Surgery, University of Nottingham Hospitals NHS Trust, Queens Medical Centre, Derby Rd, Nottingham, NG7 2UH, UK

    J. Millard, N. Fraser & R. J. Stewart

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  1. J. Millard
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  2. N. Fraser
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Correspondence to N. Fraser.

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Millard, J., Fraser, N. & Stewart, R.J. Mesenchymal hamartoma of the liver: is biopsy always necessary?. Ped Surgery Int 22, 622–625 (2006). https://doi.org/10.1007/s00383-006-1702-z

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