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Primary intracranial leiomyosarcoma: a case report and review of the literature

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Abstract

Introduction

Malignant tumours of the central nervous system (CNS) represent the second most common cancer type in the paediatric population of developed countries, and mortality caused by CNS tumours is the highest among paediatric cancers. Tumours of mesenchymal origin occurring either as primary or secondary lesions of the central nervous system are very rare in children. This paper describes the case of a 5-year-old non-immunocompromised male who presented with a right frontal primary intracranial leiomyosarcoma associated with large subdural collections.

Discussion and conclusion

Following surgical excision and adjuvant chemoradiotherapy, the patient has remained disease-free for 18 months. The literature is reviewed and the possible association of the chronic subdurals to the later development of the leiomyosarcoma explored.

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Authors and Affiliations

  1. Department of Neurosurgery, Southern General Hospital, Glasgow, UK

    C. S. Mathieson & E. J. St George

  2. Department of Neuropathology, Southern General Hospital, Glasgow, UK

    W. Stewart

  3. Department of Neurooncology, Royal Hospital for Sick Children, Glasgow, UK

    J. Sastry & S. Jamal

Authors
  1. C. S. Mathieson
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  2. E. J. St George
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  3. W. Stewart
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  4. J. Sastry
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  5. S. Jamal
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Correspondence to C. S. Mathieson.

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Mathieson, C.S., St George, E.J., Stewart, W. et al. Primary intracranial leiomyosarcoma: a case report and review of the literature. Childs Nerv Syst 25, 1013–1017 (2009). https://doi.org/10.1007/s00381-009-0845-3

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  • DOI: https://doi.org/10.1007/s00381-009-0845-3

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