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Diffraction under total internal reflection for micro-fluidic analysis

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Abstract

This work presents the principles of a novel micro-optical system for micro- and nano-fluidic analysis. It is based on diffraction, occurring in total internal reflection conditions. The developed detector is integrated in an autonomous micro-fluidic device, produced by a unique combination of different techniques for micro- and nano-structuring and micro-machining. The micro-fluidic sensor is examined both experimentally and theoretically with respect to the parameters of the light and the diffraction grating. The most beneficial configurations with respect to maximum sensitivity towards the fluidic optical constants are discussed. Optical experiments show sensitivity of 5×10-4 to the fluidic refractive index and of 3.5×106 m-1 to the absorption coefficient. Envisioned applications of the integrated micro-sensor are concentration and composition analysis, environmental protection control, medical, biological and chemical diagnostics, and so on.

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Authors and Affiliations

  1. Institute of Nanostructure Technology and Analytics (INA), University of Kassel, Heinrich-Plett-Str. 40, 34132, Kassel, Germany

    Y. Sarov, T. Ivanov, K. Ivanova & I.W. Rangelow

  2. Central Laboratory of Optical Storage and Processing of Information, Bulgarian Academy of Sciences, P.O. Box 95, 1113, Sofia, Bulgaria

    Y. Sarov

  3. Institute of Electronics, Bulgarian Academy of Sciences, 72 Tsarigradsko Chaussee, 1784, Sofia, Bulgaria

    V. Sarova

  4. Polymer Institute, Slovak Academy of Sciences, 9 Dubravska cesta, 842 36, Bratislava, Slovakia

    I. Capek

Authors
  1. Y. Sarov
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  2. T. Ivanov
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  3. K. Ivanova
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  4. V. Sarova
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  5. I. Capek
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  6. I.W. Rangelow
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Corresponding author

Correspondence to Y. Sarov.

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PACS

07.07.Df; 81.16.-c; 78.20.Ci; 81.70.Jb

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Sarov, Y., Ivanov, T., Ivanova, K. et al. Diffraction under total internal reflection for micro-fluidic analysis. Appl. Phys. A 84, 191–196 (2006). https://doi.org/10.1007/s00339-006-3597-x

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  • DOI: https://doi.org/10.1007/s00339-006-3597-x

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