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Diagnostic accuracy of dual-source CT coronary angiography with prospective ECG-triggering on different heart rate patients

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Abstract

Objective

To evaluate the diagnostic accuracy of dual-source CT (DSCT) prospective ECG-triggering coronary angiography in patients with different heart rate (HR).

Methods

103 patients with suspected coronary artery disease underwent DSCT prospective ECG-triggered coronary angiography and invasive coronary angiography (ICA). The patients were grouped by HR during CT scans: low HR (≤60 bpm, n = 34); medium HR (60 < HR ≤ 70 bpm, n = 36) and high HR (>70 bpm, n = 33). The sensitivity and specificity of DSCT in detecting ≥50% stenosis were compared among subgroups where ICA was the gold standard. Image quality was scored using a 4-point scale.

Results

A total of 1,580 (95.9%) coronary artery segments were evaluable. Sensitivity and specificity were 82.8% and 98.4%, 88.3% and 98.7%, and 80.3% and 98.6% for different subgroups (all p > 0.05). The overall area under the curve of the receiver-operating characteristic analysis was 0.94. The image quality scores were 3.1 ± 0.3, 3.1 ± 0.3 and 3.0 ± 0.4 for subgroups (p > 0.05). The overall average effective radiation dose was 3.60 ± 1.60 mSv.

Conclusion

DSCT coronary angiography with prospective ECG-triggering could be just as accurate in patients with medium to high HR compared to those with low HR.

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Acknowledgement

This study was granted by the Ministry of Science and Technology of China, Grant NO. 2007BAI05B02.

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Authors and Affiliations

  1. Department of Radiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, #167 Bei-Li-Shi Street, Beijing, 100037, China

    Ming-li Sun, Bin Lu, Lei Han, Gang Liu, Fang-Fang Yu, Zhi-hui Hou, Yang Gao, Hong-yu Wang & Shiliang Jiang

  2. CT Research Collaboration, Siemens Healthcare, Shang Hai, China

    Run-ze Wu & Laura Johnson

  3. Department of Cardiology, Division of Coronary Heart Disease, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Yue-jin Yang & Shu-bin Qiao

Authors
  1. Ming-li Sun
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  2. Bin Lu
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  3. Run-ze Wu
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  4. Laura Johnson
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  5. Lei Han
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  6. Gang Liu
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  7. Fang-Fang Yu
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  8. Zhi-hui Hou
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  9. Yang Gao
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  10. Hong-yu Wang
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  11. Shiliang Jiang
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  12. Yue-jin Yang
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  13. Shu-bin Qiao
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Corresponding author

Correspondence to Bin Lu.

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Sun, Ml., Lu, B., Wu, Rz. et al. Diagnostic accuracy of dual-source CT coronary angiography with prospective ECG-triggering on different heart rate patients. Eur Radiol 21, 1635–1642 (2011). https://doi.org/10.1007/s00330-011-2107-5

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  • DOI: https://doi.org/10.1007/s00330-011-2107-5

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