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Lumbar intervertebral disc abnormalities: comparison of quantitative T2 mapping with conventional MR at 3.0 T

  • Musculoskeletal
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Abstract

Objective

To assess the relationship of morphologically defined lumbar disc abnormalities with quantitative T2 mapping.

Methods

Fifty-three patients, mean age 39 years, with low back pain were examined by MRI at 3 T (sagittal T1-fast spin echo (FSE), three-plane T2-FSE for morphological MRI, multi-echo spin echo for T2 mapping). All discs were classified morphologically. Regions of interest (ROIs) for the annulus were drawn. The space in between was defined as the nucleus pulposus (NP). To evaluate differences between the classified groups, univariate ANOVA with post hoc Games–Howell and paired two-tailed t tests were used.

Results

In 265 discs we found 39 focal herniations, 10 annular tears, 123 bulging discs and 103 “normal discs”. T2 values of the NP between discs with annular tear and all other groups were statistically significantly different (all p ≤ 0.01). Discs with annular tears showed markedly lower NP T2 values than discs without. The difference in NP T2 values between discs with focal herniation and normal discs (p = 0.005) was statistically significant. There was no difference in NP T2 values between bulging and herniated discs (p = 0.11)

Conclusion

Quantitative T2 mapping of the nucleus pulposus of the intervertebral disc in the lumbar spine at 3 T reveals significant differences in discs with herniation and annular tears compared with discs without these abnormalities.

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Authors and Affiliations

  1. Department of Radiology, MR Centre-Highfield MR, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria

    Siegfried Trattnig, David Stelzeneder, Sabine Goed, Michael Reissegger, Pavol Szomolanyi & Goetz H. Welsch

  2. Austrian Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Clinical and Experimental Traumatology, Vienna, Austria

    Siegfried Trattnig

  3. Orthopedic Surgery Department, Inselspital Berne, Berne, Switzerland

    Tallal C. Mamisch

  4. Department of Physical Medicine and Rehabilitation, Medical University of Vienna, Vienna, Austria

    Tatjana Paternostro-Sluga

  5. Department of Radiology, Medical University of Vienna, Vienna, Austria

    Michael Weber

  6. Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia

    Pavol Szomolanyi

  7. Department of Trauma Surgery, University Hospital of Erlangen, Erlangen, Germany

    Goetz H. Welsch

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  1. Siegfried Trattnig
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Correspondence to Siegfried Trattnig.

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Trattnig, S., Stelzeneder, D., Goed, S. et al. Lumbar intervertebral disc abnormalities: comparison of quantitative T2 mapping with conventional MR at 3.0 T. Eur Radiol 20, 2715–2722 (2010). https://doi.org/10.1007/s00330-010-1843-2

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  • DOI: https://doi.org/10.1007/s00330-010-1843-2

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