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Bibliometric analysis of publications on enthesitis in spondyloarthritis in 2012–2021 based on web of science core collection databases

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Abstract

Enthesitis, a characteristic of spondyloarthritis, has been paid considerable attention by researchers, and numerous enthesitis-related studies have been published in recent years. However, no study has been conducted to analyze enthesitis-related researches with bibliometric methods. This study aimed to provide a broad understanding of enthesitis-related researches and explore the direction of hot topics and future research trends from a bibliometric perspective. The global literatures on enthesitis published from 2012 to 2021 were scanned in the Web of Science Core Collection databases. Visualization and bibliometric analyses were generated by an online bibliometric platform and VOSviewer software to explore the hot topics and research trends. A total of 1,181 documents were included in this study. Publications were mainly from these countries in North America and Western Europe. Among these countries, the United States was the leading country with the maximum publication counts (210), highest h-index (47), and largest collaboration network as of June 29, 2022. The most influential journal and powerful author were Journal of Rheumatology and Professor Mease PJ, respectively. Co-occurrence analysis of keywords identified that “axial spondyloarthritis”, “interleukin 23”, and “secukinumab” might be the future hotspots. More and more attention had been paid to enthesitis in the past 10 years. Present studies focused on the effect of inflammatory cytokines involved in the pathogenesis and the development of antibodies against these factors. These studies played a key role in understanding the research direction and subsequent management of enthesitis, and helped researchers extract hidden valuable information for further study.

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References

  1. Sieper J, Poddubnyy D (2017) Axial spondyloarthritis. Lancet 390(10089):73–84

    Article  Google Scholar 

  2. McGonagle D, Gibbon W, Emery P (1998) Classification of inflammatory arthritis by enthesitis. Lancet 352(9134):1137–1140

    Article  CAS  Google Scholar 

  3. Gracey E, Burssens A, Cambré I et al (2020) Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis. Nat Rev Rheumatol 16(4):193–207

    Article  Google Scholar 

  4. Rizzo A, Guggino G, Ferrante A, Ciccia F (2018) Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis. Front Med (Lausanne) 5:63

    Article  Google Scholar 

  5. Sharif K, Bridgewood C, Dubash S, McGonagle D (2020) Intestinal and enthesis innate immunity in early axial spondyloarthropathy. Rheumatology (Oxford) 59(Suppl4):iv67–iv78

    Article  CAS  Google Scholar 

  6. Akyol A, Kocyigit BF (2021) Publication activity in the field of Sjögren’s syndrome: a ten-year web of science based analysis. Rheumatol Int 41(4):763–769

    Article  Google Scholar 

  7. Kocyigit BF, Akyol A (2021) Bibliometric analysis of publication activity in the field of familial Mediterranean fever in 2010–2019: a Scopus-based study. Rheumatol Int 41(11):2015–2023

    Article  Google Scholar 

  8. Wu H, Cheng K, Guo Q et al (2021) Mapping knowledge structure and themes trends of osteoporosis in rheumatoid arthritis: a bibliometric analysis. Front Med (Lausanne) 8:787228

    Article  Google Scholar 

  9. Akyol A, Kocyigit BF (2021) Ankylosing spondylitis rehabilitation publications and the global productivity: a web of science-based bibliometric analysis (2000–2019). Rheumatol Int 41(11):2007–2014

    Article  Google Scholar 

  10. Tang F, Dai WB, Li XL, Turghun D, Huang H, Fan YQ (2021) Publication trends and hot spots in femoroacetabular impingement research: a 20-year bibliometric analysis. J Arthroplasty 36(8):2698–2707

    Article  Google Scholar 

  11. Zhang Y, Xu Y, Li S (2021) Bibliometrics analysis of diagnostic test accuracy studies of bladder cancer. Dis Markers 2021:8870353

    Google Scholar 

  12. Sherlock JP, Joyce-Shaikh B, Turner SP et al (2012) IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells. Nat Med 18(7):1069–1076

    Article  CAS  Google Scholar 

  13. Benham H, Rehaume LM, Hasnain SZ et al (2014) Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis Rheumatol 66(7):1755–1767

    Article  CAS  Google Scholar 

  14. Wu H, Li Y, Tong L, Wang Y, Sun Z (2021) Worldwide research tendency and hotspots on hip fracture: a 20-year bibliometric analysis. Arch Osteoporos 16(1):73

    Article  Google Scholar 

  15. Mease PJ, Fleischmann R, Deodhar AA et al (2014) Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA). Ann Rheum Dis 73(1):48–55

    Article  CAS  Google Scholar 

  16. Mease PJ, Armstrong AW (2014) Managing patients with psoriatic disease: the diagnosis and pharmacologic treatment of psoriatic arthritis in patients with psoriasis. Drugs 74(4):423–441

    Article  CAS  Google Scholar 

  17. de Winter JJ, van Mens LJ, van der Heijde D, Landewé R, Baeten DL (2016) Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis. Arthritis Res Ther 18(1):196

    Article  Google Scholar 

  18. Schett G, Lories RJ, D’Agostino MA et al (2017) Enthesitis: from pathophysiology to treatment. Nat Rev Rheumatol 13(12):731–741

    Article  CAS  Google Scholar 

  19. Feld J, Chandran V, Haroon N, Inman R, Gladman D (2018) Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison. Nat Rev Rheumatol 14(6):363–371

    Article  Google Scholar 

  20. Sieper J, Poddubnyy D, Miossec P (2019) The IL-23-IL-17 pathway as a therapeutic target in axial spondyloarthritis. Nat Rev Rheumatol 15(12):747–757

    Article  CAS  Google Scholar 

  21. McGonagle DG, McInnes IB, Kirkham BW, Sherlock J, Moots R (2019) The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies. Ann Rheum Dis 78(9):1167–1178

    Article  CAS  Google Scholar 

  22. McInnes IB, Behrens F, Mease PJ et al (2020) Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): a double-blind, parallel-group, randomised, active-controlled, phase 3b trial. Lancet 395(10235):1496–1505

    Article  CAS  Google Scholar 

  23. Armstrong AW, Read C (2020) Pathophysiology, clinical presentation, and treatment of psoriasis: a review. JAMA 323(19):1945–1960

    Article  CAS  Google Scholar 

  24. Mease PJ, Landewé R, Rahman P et al (2021) Secukinumab provides sustained improvement in signs and symptoms and low radiographic progression in patients with psoriatic arthritis: 2-year (end-of-study) results from the FUTURE 5 study. RMD Open 7(2):e001600

    Article  Google Scholar 

  25. Braun J, Baraliakos X, Deodhar A et al (2019) Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study. Rheumatology (Oxford) 58(5):859–868

    Article  CAS  Google Scholar 

  26. Ritchlin C, Adamopoulos IE (2021) Axial spondyloarthritis: new advances in diagnosis and management. BMJ 372:m4447

    Article  Google Scholar 

  27. Gossec L, Siebert S, Bergmans P et al (2022) Persistence and effectiveness of the IL-12/23 pathway inhibitor ustekinumab or tumour necrosis factor inhibitor treatment in patients with psoriatic arthritis: 1-year results from the real-world PsABio Study. Ann Rheum Dis 81(6):823–830

    Article  CAS  Google Scholar 

  28. Deodhar A, Gensler LS, Sieper J et al (2019) Three multicenter, randomized, double-blind, placebo-controlled studies evaluating the efficacy and safety of ustekinumab in axial spondyloarthritis. Arthritis Rheumatol 71(2):258–270

    Article  CAS  Google Scholar 

  29. Braun J, Landewé RB (2022) No efficacy of anti-IL-23 therapy for axial spondyloarthritis in randomised controlled trials but in post-hoc analyses of psoriatic arthritis-related “physician-reported spondylitis.” Ann Rheum Dis 81(4):466–468

    Article  CAS  Google Scholar 

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Funding

This research does not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Medical School of Chinese PLA, Beijing, 100853, China

    Yinan Zhang

  2. Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China

    Yinan Zhang, Lidong Hu, Simin Liao, Yiwen Wang, Xiaojian Ji, Xingkang Liu, Feng Huang & Jian Zhu

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  1. Yinan Zhang
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  2. Lidong Hu
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  4. Yiwen Wang
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  7. Feng Huang
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  8. Jian Zhu
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Contributions

YZ and LH contributed equally to this manuscript. Conceptualization: YZ, LH, FH, and JZ. Data curation: YZ, LH, and SL. Formal analysis: YZ, LH, YW, XJ, and XL. Software: YZ, and LH. Writing—original draft: YZ. Writing—review and editing: YZ, LH, SL, YW, XJ and XL, FH, and JZ. Supervision: LH, XJ, FH and JZ.

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Correspondence to Jian Zhu.

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Zhang, Y., Hu, L., Liao, S. et al. Bibliometric analysis of publications on enthesitis in spondyloarthritis in 2012–2021 based on web of science core collection databases. Rheumatol Int 43, 173–182 (2023). https://doi.org/10.1007/s00296-022-05227-9

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  • DOI: https://doi.org/10.1007/s00296-022-05227-9

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