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Bioptische Diagnostik der chronischen Hepatitis

Ergebnisse einer evidenzbasierten Konsensuskonferenz der Deutschen Gesellschaft für Pathologie (DGP), der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) und des Kompetenznetzes Hepatitis (HepNet)

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Notes

  1. * Empfehlungsklassen gemäß Leitlinienmanual der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften und der Ärztlichen Zentralstelle Qualitätssicherung (http://www.dgsuchtmedizin.de/fix/leitlinien/aezq220.pdf).

Literatur

  1. Alvarez F, Berg PA, Bianchi FB et al. (1999) International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 31:929–938 (IV)

    Article  CAS  PubMed  Google Scholar 

  2. Batts KP, Ludwig J (1995) Chronic hepatitis—an update on terminology and reporting. Am J Surg Pathol 19:1409–1417 (IV)

    CAS  PubMed  Google Scholar 

  3. Bedossa P, Poynard T for the METAVIR Cooperative Study Group (1996) An algorithm for the grading of activity in chronic hepatitis C. Hepatology 24:289–293 (III)

    Article  CAS  PubMed  Google Scholar 

  4. Chevallier M, Guerret S, Chossegros P et al. (1994) A histological semiquantitative scoring system for evaluation of hepatic fibrosis in needle liver biopsy specimens: comparison with morphometric studies. Hepatology 20:349–355 (II b)

    Article  CAS  PubMed  Google Scholar 

  5. Conn HO (1991) Liver biopsy: increased risks in patients with cancer. Hepatology 14:206–209 (III)

    CAS  PubMed  Google Scholar 

  6. Crawford AR, Lin XZ, Crawford JM (1998) The normal adult human liver biopsy: a quantitative reference standard. Hepatology 28:323–331 (II b)

    CAS  PubMed  Google Scholar 

  7. De Groote J, Desmet V, Gedigk P et al. (1968) A classification of chronic hepatitis. Lancet ii:626–628

    Google Scholar 

  8. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ (1994) Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19:1513–1520 (IV)

    Article  CAS  PubMed  Google Scholar 

  9. Dienstag JL (2002) The role of liver biopsy in chronic hepatitis C. Hepatology 36:S152–S160 (IV)

    Article  PubMed  Google Scholar 

  10. Dries V, von Both I, Müller M et al. (1999) Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum. Hepatology 29:223–229 (II b)

    CAS  PubMed  Google Scholar 

  11. EASL International Consensus Conference on Hepatitis C (1999) Consensus statement. J Hepatol 30:956–961 (IV)

    Article  PubMed  Google Scholar 

  12. Gebo KA, Herlong HF, Torbenson MS et al. (2002) Role of liver biopsy in management of chronic hepatitis C: a systematic review. Hepatology 36:S161–S172 (III)

    Article  PubMed  Google Scholar 

  13. Goldin RD, Goldin JG, Burt AD et al. (1996) Intra-observer and inter-observer variation in the histopathological assessment of chronic viral hepatitis. J Hepatol 25:649–654 (III)

    Article  CAS  PubMed  Google Scholar 

  14. Gordon SC, Veneri RJ, McFadden RF et al. (1991) Major hemorrhage after percutaneous liver biopsy in patients with AIDS. Gastroenterology 100:1787 (IV)

    Google Scholar 

  15. Grant, A, Neuberger J (1999) Guidelines on the use of liver biopsy in clinical practice. Gut 45 (Suppl IV):1–11 (IV)

    PubMed  Google Scholar 

  16. Hopf U, Niederau C, Kleber G, Fleig WE (1997) Behandlung der chronischen Virushepatitis B/D und der akuten und chronischen Virushepatitis C. Konsensus der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten. Z Gastroenterol 35:971–986 (IV)

    CAS  PubMed  Google Scholar 

  17. Hederström E, Forsberg L, Florén CH, Prytz H (1989) Liver biopsy complications monitored by ultrasound. J Hepatol 8:94–98 (IV)

    Article  PubMed  Google Scholar 

  18. Ishak KG, Baptista A, Bianchi L et al. (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22:696–699 (IV)

    Article  CAS  PubMed  Google Scholar 

  19. Knodell RG, Ishak KG, Black WC et al. (1981) Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1:431–435

    CAS  PubMed  Google Scholar 

  20. Marcellin P, Asselah T, Boyer N (2002) Fibrosis and disease progression in hepatitis C. Hepatology 36:S47–S56 (IV)

    Article  PubMed  Google Scholar 

  21. McGill DB, Rakela J, Zinsmeister AR, Ott BJ (1990) A 21-year experience with major hemorrhage after percutaneous liver biopsy. Gastroenterology 99:1396–1400 (II a)

    CAS  PubMed  Google Scholar 

  22. Miniuk GY, Sutherland LR, Wiseman DA et al. (1987) Prospective study of the incidence of ultrasound-detected intrahepatic and subcapsular hematomas in patients randomized to 6 or 24 hours of bedrest after percutaneous liver biopsy. Gastroenterology 92:290–293 (I b)

    PubMed  Google Scholar 

  23. National Institutes of Health consensus development conference statement (2002) Management of hepatitis C: 2002. Hepatology 36:S3–S20 (IV)

    Article  PubMed  Google Scholar 

  24. Özdogan M, Özgür O, Boyacioglu S et al. (1996) Percutaneous liver biopsy complications in patients with chronic renal failure. Nephron 74:442–444 (III)

    Google Scholar 

  25. Pradat P, Poynard T, Alberti A et al. (2002) Predictive value of ALT levels for histologic findings in chronic hepatitis C: a European collaborative study. Hepatology 36:973–977 (III)

    PubMed  Google Scholar 

  26. Piccinino F, Sagnelli E, Pasquale G, Giusti G (1986) Complications following percutaneous liver biopsy. A multicentre retrospective study on 68,276 biopsies. J Hepatol 2:165–173 (III)

    CAS  PubMed  Google Scholar 

  27. Scheuer PJ (1991) Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 13:372–374 (IV)

    CAS  PubMed  Google Scholar 

  28. Terjung B, Lemnitzer I, Dumoulin FL et al. (2003) Bleeding complications after percutaneous liver biopsy: an analysis of risk factors. Digestion 67:138–145 (III)

    Article  PubMed  Google Scholar 

  29. The METAVIR Cooperative Group (1994) Inter- and intra-observer variation in the assessment of liver biopsy of chronic hepatitis C. Hepatology 20:15–20 (III)

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Pathologisches Institut, Universität Heidelberg

    P. Schirmacher

  2. Klinik und Poliklinik für Innere Medizin I, Universität Halle-Wittenberg

    W. E. Fleig

  3. Institut für Pathologie, Universität Leipzig

    A. Tannapfel

  4. Institut für Pathologische Anatomie, Universität Graz, Österrreich

    C. Langner & H. Denk

  5. Institut für Pathologie, Ulm

    V. Dries

  6. Institut für Pathologie, Universitätsspital Basel, Schweiz

    L. Terracciano

  7. Institut für Pathologie, Universität zu Köln

    H. P. Dienes

  8. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg

    P. Schirmacher

Authors
  1. P. Schirmacher
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  2. W. E. Fleig
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  3. A. Tannapfel
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  4. C. Langner
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  5. V. Dries
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  6. L. Terracciano
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  7. H. Denk
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  8. H. P. Dienes
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Corresponding author

Correspondence to P. Schirmacher.

Additional information

(Literatur: Evidenzstärke gemäß Ärztliche Zentralstelle Qualitätssicherung in Klammern)

Für die Konsensusgruppe „Bioptische Diagnostik der chronischen Hepatitis“: Alle Autoren und Mitglieder der Konsensusgruppe sind am Ende der Publikation aufgeführt.

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Schirmacher, P., Fleig, W.E., Tannapfel, A. et al. Bioptische Diagnostik der chronischen Hepatitis. Pathologe 25, 337–348 (2004). https://doi.org/10.1007/s00292-004-0692-7

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  • DOI: https://doi.org/10.1007/s00292-004-0692-7

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