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Co-existence of a novel translocation t(11;22)(q23;q12.1) with PML-RARA in acute promyelocytic leukemia: a case report

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Fig. 1

Data availability

The datasets analyzed in the current study are available in the NCBI’s Sequence Read Archive (SRA) repository, with accession number PRJNA834561 (https://www.ncbi.nlm.nih.gov/bioproject/834561) for genomic DNA and RNA sequencing.

Abbreviations

APL:

Acute promyelocytic leukemia

AML:

Acute myeloid leukemia

RT-PCR:

Reverse transcription PCR

BM:

Bone marrow

FISH:

Fluorescence in situ hybridization

RT-qPCR:

Real-time polymerase chain reaction

ATRA:

All-trans retinoic acid

References

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Funding

This study was supported by a grant (NRF- 2020R1C1C1008535) from the National Research Foundation of Korea and Soonchunhyang University Research Fund, Korea.

Author information

Authors and Affiliations

  1. Department of Laboratory Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, 59 Daesaqwan-ro, Yongsan-gu, Seoul, 04401, Republic of Korea

    Woo Yong Shin, Jung-Ah Kim, Hae In Bang, Jieun Kim & Rojin Park

  2. Division of Hematology and Oncology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea

    Seug Yun Yoon & Jong-Ho Won

  3. Department of Interdisciplinary Program in Biomedical Science, Graduate School, Soonchunhyang University, Asan, Chungcheongnam-do, Republic of Korea

    Ho Hyun Song

Authors
  1. Woo Yong Shin
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  2. Jung-Ah Kim
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  4. Hae In Bang
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  5. Jong-Ho Won
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  7. Jieun Kim
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  8. Rojin Park
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Contributions

WS participated in writing the paper. JK and SY participated in sample collection and reviewed clinical data. HB and JW advised on research methodology. JK participated in writing the manuscript, research design, and acquisition of financial support. RP participated in research work.

Corresponding author

Correspondence to Jieun Kim.

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Ethics approval

This study was approved by the Institutional Review Board (IRB) of Soonchunhyang University Seoul Hospital. The requirement for informed consent was waived (IRB No. 2021–12-007).

Competing interests

The authors declare no competing interests.

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Shin, W.Y., Kim, JA., Yoon, S.Y. et al. Co-existence of a novel translocation t(11;22)(q23;q12.1) with PML-RARA in acute promyelocytic leukemia: a case report. Ann Hematol 101, 2369–2371 (2022). https://doi.org/10.1007/s00277-022-04911-x

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  • DOI: https://doi.org/10.1007/s00277-022-04911-x

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