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Long-Term Outcomes Following Transarterial Embolisation of Proximal Type I Endoleaks Post-EVAR

  • Clinical Investigation
  • Arterial Interventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

To describe the long-term outcomes following transarterial embolisation for type Ia endoleaks (ELIa) in patients who failed or were unsuitable for standard endovascular/surgical options.

Materials and Methods

A retrospective single-centre observational study was performed between October 2010 and April 2018. Technical success rates and long-term outcomes were evaluated. A sub-analysis was performed comparing outcomes of covered aortic endografts and Nellix endovascular aneurysm sealing systems.

Results

A total of 34 transcatheter embolisations were performed for ELIa in 27 patients (13 endografts and 14 patients with Nellix systems). A combination of Onyx and coils was used most frequently (18/34), followed by Onyx alone (14/34) and coils alone (2/34). Technical success was achieved in 33/34 (97%) procedures . Seven early complications occurred with no immediate mortality, 5 of which involved migration/reflux of embolic into the endograft—all successfully managed via endovascular approach. Following the surveillance period (mean 25 months), 13/26 (50%) of patients were free from recurrent endoleak. Sac expansion occurred in 42% (11/26). 21/26 patients died; 6 due to aneurysm sac rupture, 10 due to unrelated causes, and 5 had no cause of death available. No significant difference in survival was found between patients with an endograft or Nellix graft—Chi-squared value − 0.011 (p < 0.05 = 3.84).

Conclusions

Transcatheter embolisation for type Ia endoleaks is a safe and effective option in a select patient cohort—where traditional endovascular and surgical options are unsuitable or have failed. The procedure may prevent recurrence in some whilst delaying rupture and death in others.

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References

  1. Chaikof EL, Dalman RL, Eskandari MK, et al. The society for vascular surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018;67(1):2-77.e2. https://doi.org/10.1016/j.jvs.2017.10.044.

    Article  PubMed  Google Scholar 

  2. Kaufman JA. Vascular interventions. In: Kaufman JA, Lee MJ, editors. Vascular and interventional radiology: The Requisites. Elsevier Saunders; 2013. p. 86–95.

  3. Moll FL, Powell JT, Fraedrich G, et al. Management of abdominal aortic aneurysms clinical practice guidelines of the European society for vascular surgery. Eur J Vasc Endovasc Surg. 2011;41:S1e58.

    Article  Google Scholar 

  4. Harris PL, Vallabhaneni SR, Desgranges P, et al. Incidence and risk factors of late rupture, conversion, and death after endovascular repair of infrarenal aortic aneurysms: the EUROSTAR experience. European collaborators on stent/graft techniques for aortic aneurysm repair. J Vasc Surg. 2000;32:739.

    Article  CAS  PubMed  Google Scholar 

  5. Ameli-Renani S, Pavlidis V, Morgan RA. Secondary endoleak management following TEVAR and EVAR. Cardiovasc Interv Radiol. 2020;43(12):1839–54. https://doi.org/10.1007/s00270-020-02572-9.

    Article  Google Scholar 

  6. Perini P, BianchiniMassoni C, Mariani E, et al. Systematic review and meta-analysis of the outcome of different treatments for type 1a endoleak after EVAR. Ann Vasc Surg. 2019;60:435-446.e1. https://doi.org/10.1016/j.avsg.2019.03.032.

    Article  PubMed  Google Scholar 

  7. Ameli-Renani S, Pavlidis V, Morgan RA. Early and midterm outcomes after transcatheter embolization of type I endoleaks in 25 patients. J Vasc Surg. 2017;65(2):346–55. https://doi.org/10.1016/j.jvs.2016.06.101.

    Article  PubMed  Google Scholar 

  8. Chun JY, Morgan R. Transcatheter embolisation of type 1 endoleaks after endovascular aortic aneurysm repair with Onyx: when no other treatment option is feasible. Eur J Vasc Endovasc Surg. 2013;45(2):141–4. https://doi.org/10.1016/j.ejvs.2012.11.010.

    Article  PubMed  Google Scholar 

  9. Marchiori E, Ibrahim A, Schäfers JF, Oberhuber A. Embolization for type Ia endoleak after EVAR for abdominal aortic aneurysms: a systematic review of the literature. Biomedicines. 2022;10(6):1442. https://doi.org/10.3390/biomedicines10061442.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Golzarian J, Struyven J, Abada HT, Wery D, Dussaussois L, Madani A, Ferreira J, Dereume JP. Endovascular aortic stent-grafts: transcatheter embolization of persistent perigraft leaks. Radiology. 1997;202:731–4.

    Article  CAS  PubMed  Google Scholar 

  11. Amesur NB, Zajko AB, Orons PD, Makaroun MS. Embolo-therapy of persistent endoleaks after endovascular repair of abdominal aortic aneurysm with the Ancure-endovascular technologies endograft system. J Vasc Interv Radiol. 1999;10:1175–82.

    Article  CAS  PubMed  Google Scholar 

  12. Faries PL, Cadot H, Agarwal G, Kent KC, Hollier LH, Marin ML. Management of endoleak after endovascular aneurysm repair: cuffs, coils, and conversion. J Vasc Surg. 2003;37:1155–61.

    Article  PubMed  Google Scholar 

  13. Maldonado TS, Rosen RJ, Rockman CB, Adelman MA, Bajakian D, Jacobowitz GR, Riles TS, Lamparello PJ. Initial successful management of type I endoleak after endovascular aortic aneurysm repair with N-Butyl cyanoacrylate adhesive. J Vasc Surg. 2003;38:664–70.

    Article  CAS  PubMed  Google Scholar 

  14. Choi SY, Lee DY, Lee K-H, Ko Y-G, Choi D, Shim W-H, Won JY. Treatment of type I Endoleaks after endovascular aneurysm repair of infrarenal abdominal aortic aneurysm: usefulness of N-Butyl cyanoacrylate embolization in cases of failed secondary endovascular intervention. J Vasc Interv Radiol. 2011;22:155–62.

    Article  PubMed  Google Scholar 

  15. Henrikson O, Roos H, Falkenberg M. Ethylene vinyl alcohol copolymer (Onyx) to seal type 1 endoleak. New Tech Vasc. 2011;19:77–81.

    Google Scholar 

  16. Eberhardt KM, Sadeghi-Azandaryani M, Worlicek S, Koeppel T, Reiser MF, Treitl M. Treatment of type I endoleaks using transcatheter embolization with Onyx. J Endovasc Ther. 2014;21:162–71.

    Article  PubMed  Google Scholar 

  17. Ameli-Renani S, Das R, Weller A, Chung R, Morgan RA. Embolisation of a proximal type I endoleak Post-Nellix aortic aneurysm repair complicated by reflux of Onyx into the Nellix endograft limb. Cardiovasc Interv Radiol. 2014;38:747–51.

    Article  Google Scholar 

  18. Graif A, Vance AZ, Garcia MJ, Lie KT, McGarry MK, Leung DA. Transcatheter embolization of type I endoleaks associated with endovascular abdominal aortic aneurysm repair using ethylene vinyl alcohol copolymer. Vasc Endovasc Surg. 2017;51:28–32.

    Article  Google Scholar 

  19. Marcelin C, Le Bras Y, Petitpierre F, Midy D, Grenier N, Ducasse E, Cornélis F. Embolization for persistent type IA endoleaks after chimney endovascular aneurysm repair with Onyx®. Diagn Interv Imaging. 2017;98:849–55.

    Article  CAS  PubMed  Google Scholar 

  20. Ierardi AM, Franchin M, Fontana F, Piffaretti G, Crippa M, Angileri SA, Magenta Biasina A, Piacentino F, Tozzi M, Pinto A, et al. The role of ethylene-vinyl alcohol copolymer in association with other embolic agents for the percutaneous and endovascular treatment of type Ia endoleak. Radiol Med. 2018;123:638–42.

    Article  PubMed  Google Scholar 

  21. Marchiori E, Herten M, Bosiers M, Schwindt A, Bisdas T, Austermann M, Torsello G, Stavroulakis K. Effectiveness of intra-arterial aneurysm sac embolization for type Ia endoleak after endovascular aneurysm repair. J Vasc Interv Radiol. 2019;30:531–8.

    Article  PubMed  Google Scholar 

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Correspondence to Shyamal Patel.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Ethical approval was sought, but for this type of study formal ethical approval was not required.

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Patel, S., Pavlidis, V., Ameli-Renani, S. et al. Long-Term Outcomes Following Transarterial Embolisation of Proximal Type I Endoleaks Post-EVAR. Cardiovasc Intervent Radiol 46, 428–435 (2023). https://doi.org/10.1007/s00270-022-03342-5

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  • DOI: https://doi.org/10.1007/s00270-022-03342-5

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