Abstract
Background
Desire for improved aesthetic contour of the lower third of the face has resulted in an increase in chin augmentation. Although many fillers, including hyaluronic acid (HA), autologous fat and stromal vascular fraction gel (SVF-gel), have been used to improve facial morphology, chin augmentation requires fillers that provide greater support.
Methods
The elastic and viscous moduli of SVF-gel and Coleman fat were assessed in vitro by rheological testing, whereas their elasticity were evaluated in vivo by ultrasonic elastography. Results in vitro were compared with those of highly elastic HA (HE-HA) and highly viscous HA (HV-HA), whereas results in vivo were compared with HE-HA. Changes in chin volume, SVF-gel retention rate and absorptivity for at least 12 months were measured by 3D white light scanning. Questionnaires were administered to assess patient satisfaction.
Results
The elastic and viscous modulus of SVF-gel was, respectively, slightly lower than HE-HA and HV-HA but higher than the other two in vitro, with the elasticity of the three layers of SVF-gel lower than HE-HA but slightly higher than normal control in vivo. The average retention rate was 62.34±3.34% at 12 months. The absorptivity of 90% of the samples was <3% from 6 to 12 months, which was considered stable. Patients expressed satisfaction with their results.
Conclusion
SVF-gel has ideal rheologic characteristics in vitro, which has slightly higher elasticity than normal fat tissue of chin in vivo, and could keep well retention rate for chin augmentation in clinic.
Level of Evidence IV
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Change history
16 June 2021
A Correction to this paper has been published: https://doi.org/10.1007/s00266-021-02409-x
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Acknowledgements
Thanks for the experimental site and equipment provided by The Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University.
Funding
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by Natural Science Foundation of Heilongjiang Province, China (QC2018102), and President Foundation of The First Affiliated Hospital of Harbin Medical University (2019B24).
Applied Technology Research and Development Project of Heilongjiang Province (GA20C019).
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Wang, Q., Chen, X., Wang, X. et al. A Reliable Method for Chin Augmentation by Mechanical Micronization of Lipoaspirates. Aesth Plast Surg 45, 1507–1517 (2021). https://doi.org/10.1007/s00266-021-02237-z
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DOI: https://doi.org/10.1007/s00266-021-02237-z