Skip to main content

Advertisement

SpringerLink
Log in

Outcomes of ankle arthrodesis in adult patients with ankle osteoarthritis in Kashin-Beck disease

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Purpose

We retrospectively evaluated the characteristics of these patients and the effectiveness of ankle arthrodesis in the treatment of ankle arthritis caused by Kashin-Beck disease (KBD).

Methods

A retrospective study of KBD patients with ankle osteoarthritis who underwent ankle arthrodesis between December 2012 and January 2022 was performed. A total of 46 patients were included. The general characteristics, clinical manifestations and imaging features of the patients were recorded and summarized. measured using the VAS score, and ankle function was assessed by the AOFAS ankle-hindfoot score.

Results

Multiple subchondral cystic changes were found in 42(91.3%) patients. The VAS scores for both resting and weight-bearing conditions were 6.28 ± 1.30 vs. 2.09 ± 1.12 (P < .001) and 6.87 ± 1.01 vs. 2.17 ± 0.98 (P < .001), respectively. The AOFAS scores were 59.17 ± 5.50 and 88.39 ± 1.42, respectively (P < .001).

Conclusions

The subchondral multiple cystic transformation of the ankle KBD has a certain suggestive role.Arthrodesis is an effective method to reduce ankle pain and improve ankle function in KBD patients with ankle osteoarthritis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig.4
Fig. 5

Similar content being viewed by others

Data availability

Raw data were generated from electronical records of the participating medical centres. Derived data supporting the findings of this study are available from the corresponding author [A.D] on request.

References

  1. Guo X, Ma WJ, Zhang F et al (2014) Recent advances in the research of an endemic osteochondropathy in China: Kashin-Beck disease. Osteoarthritis Cartilage 22(11):1774–1783. https://doi.org/10.1016/j.joca.2014.07.023

    Article  CAS  PubMed  Google Scholar 

  2. Wang K, Yu J, Liu H et al (2020) Endemic Kashin-Beck disease: a food-sourced osteoarthropathy. Semin Arthritis Rheum 50(2):366–372. https://doi.org/10.1016/j.semarthrit.2019.07.014

    Article  CAS  PubMed  Google Scholar 

  3. Xu J, Wang J, Zhao H (2023) The prevalence of Kashin-Beck disease in China: a systematic review and meta-analysis. Biol Trace Elem Res 201(7):3175–3184. https://doi.org/10.1007/s12011-022-03417-x

    Article  CAS  PubMed  Google Scholar 

  4. Xiong G (2001) Diagnostic, clinical and radiological characteristics of Kashin-Beck disease in Shaanxi Province, PR China. Int Orthop 25(3):147–150. https://doi.org/10.1007/s002640100248

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Farooq U, Xiong G, Irshad R et al (2010) Pattern of joints involvement in Kashin-Beck disease: a local osteochondropathy in China. J Ayub Med Coll Abbottabad 22(1):97–100. https://pubmed.ncbi.nlm.nih.gov/21409915/

  6. Iwasa K, Kanzaki N, Fujishiro T et al (2014) Arthroscopic ankle arthrodesis for treating osteoarthritis in a patient with kashin-beck disease. Case Rep Med 2014:931278. https://doi.org/10.1155/2014/931278

    Article  PubMed  PubMed Central  Google Scholar 

  7. Choi JY, Park SJ, Suh JS (2023) Does ankle arthrodesis induce satisfactory changes in the medial longitudinal arch height of the foot for severe varus ankle arthritis? Int Orthop 47(1):107–115. https://doi.org/10.1007/s00264-022-05645-1

    Article  PubMed  Google Scholar 

  8. Martinelli N, Bianchi A, Raggi G et al (2022) Open versus arthroscopic ankle arthrodesis in high-risk patients: a comparative study. Int Orthop 46(3):515–521. https://doi.org/10.1007/s00264-021-05233-9

    Article  PubMed  Google Scholar 

  9. Zwipp H, Rammelt S, Endres T et al (2010) High union rates and function scores at midterm followup with ankle arthrodesis using a four screw technique. Clin Orthop Relat Res 468(4):958–968. https://doi.org/10.1007/s11999-009-1074-5

    Article  PubMed  Google Scholar 

  10. Jin ZK, Xu CX, Dong XH et al (2021) Long-term outcomes of arthroscopic debridement of the knee in adults with Kashin-Beck disease: an 18-year follow-up. J Int Med Res 49(10):3000605211050781. https://doi.org/10.1177/03000605211050781

    Article  CAS  PubMed  Google Scholar 

  11. Li L, Wang Y, Zhu Z et al (2019) Conservative tibiotalocalcaneal arthrodesis for partial talar avascular necrosis in conjunction with ankle and subtalar joint osteoarthritis in Kashin-Beck disease: a case report. Medicine (Baltimore) 98(29):e16367. https://doi.org/10.1097/MD.0000000000016367

    Article  PubMed  Google Scholar 

  12. Yu FF, Ping ZG, Yao C et al (2017) Evaluation of the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease, an endemic osteoarthritis, in China. Biomed Environ Sci 30(2):150–155. https://doi.org/10.3967/bes2017.021

    Article  PubMed  Google Scholar 

  13. Shao Q, Yang H (2022) Severe deformity in long-term Kaschin-Beck disease. Rheumatology (Oxford) 61(4):1732. https://doi.org/10.1093/rheumatology/keab486

    Article  PubMed  Google Scholar 

  14. Shi Z, Pan P, Feng Y et al (2017) Environmental water chemistry and possible correlation with Kaschin-Beck Disease (KBD) in northwestern Sichuan, China. Environ Int 99:282–92. https://doi.org/10.1016/j.envint.2016.12.006

    Article  CAS  PubMed  Google Scholar 

  15. Qi F, Cui SL, Zhang B et al (2023) A study on atypical Kashin-Beck disease: an endemic ankle arthritis. J Orthop Surg Res 18(1):328. https://doi.org/10.1186/s13018-023-03633-8

    Article  PubMed  PubMed Central  Google Scholar 

  16. Barg A, Pagenstert GI, Hügle T et al (2013) Ankle osteoarthritis: etiology, diagnostics, and classification. Foot Ankle Clin 18(3):411–426. https://doi.org/10.1016/j.fcl.2013.06.001

    Article  PubMed  Google Scholar 

  17. Giannini S, Buda R, Faldini C et al (2007) The treatment of severe posttraumatic arthritis of the ankle joint. J Bone Joint Surg Am 89 Suppl 3:15–28. https://doi.org/10.2106/JBJS.G.00544

    Article  CAS  PubMed  Google Scholar 

  18. Tanaka Y, Takakura Y, Hayashi K et al (2006) Low tibial osteotomy for varus-type osteoarthritis of the ankle. J Bone Joint Surg Br 88(7):909–913. https://doi.org/10.1302/0301-620X.88B7.17325

    Article  CAS  PubMed  Google Scholar 

  19. Cheng YM, Huang PJ, Hong SH et al (2001) Low tibial osteotomy for moderate ankle arthritis. Arch Orthop Trauma Surg 121(6):355–358. https://doi.org/10.1007/s004020000243

    Article  CAS  PubMed  Google Scholar 

  20. Yang L, Sun J, Zhang Y et al (2022) Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between Kashin-Beck disease and primary osteoarthritis. Front Genet 13:942326. https://doi.org/10.3389/fgene.2022.942326

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Ling M, Sun Z, Yi Z et al (2015) Long-Term Efficacy of Arthroscopic Debridement on Knee Osteoarthritis in Patients with Kashin-Beck disease. Cell Biochem Biophys 73(1):125–8. https://doi.org/10.1007/s12013-015-0635-3

    Article  CAS  PubMed  Google Scholar 

  22. DeVries JG, Scharer BM (2023) The ankle joint: updates on ankle fusion approaches and fixation. Clin Podiatr Med Surg 40(4):681–701. https://doi.org/10.1016/j.cpm.2023.05.010

    Article  PubMed  Google Scholar 

  23. Betz MM, Benninger EE, Favre PP et al (2013) Primary stability and stiffness in ankle arthrodes-crossed screws versus anterior plating. Foot Ankle Surg 19(3):168–172. https://doi.org/10.1016/j.fas.2013.04.006

    Article  PubMed  Google Scholar 

  24. Xie Q, Sui L, Sun Y et al (2023) Comparisons of ankle arthrodesis with different internal fixation methods in the treatment of post-traumatic osteoarthritis. J Orthop Sci 27:S0949-2658. https://doi.org/10.1016/j.jos.2023.02.009

    Article  Google Scholar 

  25. Lim PQX, Lithgow MJ, Kaminski MR et al (2023) Efficacy of non-surgical interventions for midfoot osteoarthritis: a systematic review. Rheumatol Int 43(8):1409–1422. https://doi.org/10.1007/s00296-023-05324-3

    Article  PubMed  PubMed Central  Google Scholar 

  26. Wu C, Zheng J, Yao X et al (2022) Defective autophagy in chondrocytes with Kashin-Beck disease but higher than osteoarthritis. Osteoarthritis Cartilage 22(11):1936–1946. https://doi.org/10.1016/j.joca.2014.08.010

    Article  Google Scholar 

  27. Song Q, Zeng X, Huang H et al (2022) SPECT/CT imaging features of cystic degeneration of the talus and their relation to pathological findings. J Orthop Surg Res 17(1):449. https://doi.org/10.1186/s13018-022-03344-6

    Article  PubMed  PubMed Central  Google Scholar 

  28. Jin Z, Wu X, Sun Z et al (2023) Health-related quality of life in patients with Kashin-Beck disease is lower than in those with osteoarthritis: a cross-sectional study. J Orthop Surg Res 18(1):330. https://doi.org/10.1186/s13018-023-03803-8

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Funding

The author(s) received no financial support for the research, authorship, and/or publication of this article.

Author information

Authors and Affiliations

  1. Department of Hand, Foot and Microsurgery, the Affiliated Hospital of Qingdao University, No. 59, Haier Road, Qingdao City, 266000, Shandong Province, China

    Zhen Lu Cao, Chen Han Wang, Xiao Heng Ding, Zheng Dan Wang & Quan Yu Dong

Authors
  1. Zhen Lu Cao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chen Han Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Xiao Heng Ding
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zheng Dan Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Quan Yu Dong
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

All authors contributed to the study conception and design. all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Quan Yu Dong.

Ethics declarations

Ethical approval

Ethical approval was obtained from the Institutional Review Board (IRB) from the Affiliated Hospital of Qingdao University.

Conflicting interests

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. ICMJE forms for all authors are available online.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cao, Z.L., Wang, C.H., Ding, X.H. et al. Outcomes of ankle arthrodesis in adult patients with ankle osteoarthritis in Kashin-Beck disease. International Orthopaedics (SICOT) (2024). https://doi.org/10.1007/s00264-024-06195-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00264-024-06195-4

Keywords

Search

Navigation