Abstract
Purpose
It is crucially important to optimise functional outcome after fixation of trochanteric femoral fractures. While a number of risk factors that predict a poor clinical course have been identified, the influence of pre-existing radiographic osteoarthritis (OA) of the hip is unclear.
Methods
The influence of pre-existing radiographic OA of the hip on short- to mid-term functional outcome was prospectively analysed in a cohort of patients undergoing proximal femoral nailing for trochanteric fracture. OA was graded according to Kellgren and Lawrence; functional outcome was assessed at six and 12 months by the Harris hip score (HHS), the timed up and go (TUG) test and the Barthel Index.
Results
Our cohort comprised 188 patients (58 were male and 130 female), with a mean age of 82 years. At six and 12 months postoperatively, the HHS (p < 0.001 and p = 0.008, respectively) and Barthel Index (p < 0.001 and p = 0.02, respectively) correlated significantly with the grade of pre-existing OA. After adjustment for confounding variables, there was a significant association between the grade of pre-existing OA and the HHS at six months (p = 0.02). Although we observed trends suggestive of other relationships, none reached statistical significance.
Conclusions
Pre-existing radiographic OA of the hip is an important determinant of clinical outcome in elderly patients with a trochanteric femoral fracture. Further studies will be needed to establish the most effective means of restoring hip function after trochanteric femoral fracture in patients with radiographic OA of the hip.
Similar content being viewed by others
Abbreviations
- ASA:
-
American Society of Anesthesiologists
- FU:
-
Follow-up
- HSS:
-
Harris hip score
- MMSE:
-
Mini-Mental State Examination
- NSA:
-
Neck shaft angle
- OA:
-
Osteoarthritis
- PFF:
-
Proximal femoral fracture
- SD:
-
Standard deviation
- TUG:
-
Timed up and go
References
Rosengren BE, Karlsson MK (2014) The annual number of hip fractures in Sweden will double from year 2002 to 2050: projections based on local and nationwide data. Acta Orthop 85(3):234–237
Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B (2010) Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing 39(2):203–209
Khan MA, Hossain FS, Ahmed I, Muthukumar N, Mohsen A (2013) Predictors of early mortality after hip fracture surgery. Int Orthop 37(11):2119–2124
Talsnes O, Hjelmstedt F, Dahl OE, Pripp AH, Reikerås O (2011) Clinical and biochemical prediction of early fatal outcome following hip fracture in the elderly. Int Orthop 35(6):903–907
Giessauf C, Glehr M, Bernhardt GA, Seibert FJ, Gruber K, Sadoghi P, Leithner A, Gruber G (2012) Quality of life after pertrochanteric femoral fractures treated with a γ nail: a single center study of 62 patients. BMC Musculoskelet Disord 13:214
Radcliff TA, Regan E, Cowper Ripley DC, Hutt E (2012) Increased use of intramedullary nails for intertrochanteric proximal femoral fractures in veterans affairs hospitals: a comparative effectiveness study. J Bone Joint Surg Am 94(9):833–840
Bonnaire F, Lein T, Bula P (2011) Trochanteric femoral fractures: anatomy, biomechanics and choice of implants. Unfallchirurg 114(6):491–500
Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16(4):494–502
Roth T, Kammerlander C, Gosch M, Luger TJ, Blauth M (2010) Outcome in geriatric fracture patients and how it can be improved. Osteoporos Int 21:S615–S619
Matre K, Vinje T, Havelin LI, Gjertsen JE, Furnes O, Espehaug B, Kjellevold SH, Fevang JM (2013) TRIGEN INTERTAN intramedullary nail versus sliding hip screw: a prospective, randomized multicenter study on pain, function, and complications in 684 patients with an intertrochanteric or subtrochanteric fracture and one year of follow-up. J Bone Joint Surg Am 95(3):200–208
Hoffmann M, Hartel M, Rueger JM, Lehmann W (2014) Primary prosthetic replacement in per- and intertrochanteric fractures. Eur J Trauma Emerg Surg 40(3):273–277
Kim SY, Kim YG, Hwang JK (2005) Cementless calcar-replacement hemiarthroplasty compared with intramedullary fixation of unstable intertrochanteric fractures. A prospective, randomized study. J Bone Joint Surg Am 87(10):2186–2192
Shen J, Wang DL, Chen GX, Yang HL, Li L, Wei MX, Cai XQ, Yu ZH, Cheng L, Zhang XX, Zou TM (2012) Bipolar hemiarthroplasty compared with internal fixation for unstable intertrochanteric fractures in elderly patients. J Orthop Sci 17(6):722–729
Kim C, Linsenmeyer KD, Vlad S, Guermazi A, Clancy MM, Niu J, Felson DT (2014) Prevalence of radiographic and symptomatic hip osteoarthritis in an urban United States community: the Framingham osteoarthritis study. Arthritis Rheumatol 66(11):3013–3017. doi:10.1002/art.38795
Calderazzi F, Groppi G, Ricotta A, Ceccarelli F (2014) Does hip osteoarthritis have a protective effect against proximal femoral fractures? A retrospective study. Hip Int 24(3):231–236
Hutchings L, Fox R, Chesser T (2011) Proximal femoral fractures in the elderly: how are we measuring outcome? Injury 42(11):1205–1213
Lechler P, Frink M, Gulati A, Murray D, Renkawitz T, Bücking B, Ruchholtz S, Boese CK (2014) The influence of hip rotation on femoral offset in plain radiographs. Acta Orthop 85(4):389–395
Pajarinen J, Lindahl J, Savolainen V, Michelsson O, Hirvensalo E (2004) Femoral shaft medialisation and neck-shaft angle in unstable pertrochanteric femoral fractures. Int Orthop 28(6):347–353
Andruszkow H, Frink M, Frömke C, Matityahu A, Zeckey C, Mommsen P, Suntardjo S, Krettek C, Hildebrand F (2012) Tip apex distance, hip screw placement, and neck shaft angle as potential risk factors for cut-out failure of hip screws after surgical treatment of intertrochanteric fractures. Int Orthop 36(11):2347–2354
Reijman M, Hazes JM, Koes BW, Verhagen AP, Bierma-Zeinstra SM (2004) Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal. Ann Rheum Dis 63(3):226–232
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Boese, C.K., Buecking, B., Schwarting, T. et al. The influence of pre-existing radiographic osteoarthritis on functional outcome after trochanteric fracture. International Orthopaedics (SICOT) 39, 1405–1410 (2015). https://doi.org/10.1007/s00264-014-2663-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00264-014-2663-9