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Safety and accuracy of aortic and periaortic CT-guided percutaneous core needle biopsy

  • Interventional Radiology
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study was to determine the safety and accuracy of aortic and periaortic computed tomography (CT)-guided percutaneous core needle biopsy performed at a single center over 12 years.

Materials and methods

A retrospective review was conducted of cases performed between February 2010 and August 2022 in which the biopsied region was in direct contact with the aorta or great vessels including the pericardium and common iliac arteries. Clinical notes were reviewed for any early or delayed complications following the procedure, which if present were graded using the National Institute of Health’s Common Terminology Criteria for Adverse Events, version 5.0. Pathology results were compared to subsequent outside biopsy results or follow-up surgical pathology, if available, as well as subsequent clinical decision making and/or clinical course, to determine concordance. Sensitivity, specificity, predictive value, and accuracy (indicative of diagnostic yield) were calculated.

Results

32 core needle biopsies were reviewed from 30 patients (average lesion longest diameter 3.1 cm, range 0.5–10.9 cm; average needle proximity to the vessel endothelium or deep side of the pericardium 1.0 cm, range 0.3–1.8 cm). Complications occurred in 46.9% of cases (15/32), 93.3% (14/15) of which were minor and included small amounts of bleeding or pain. One patient developed a small nonemergent pneumothorax. Of biopsies obtained, 96.9% provided adequate tissue for diagnosis (31/32). When evaluating concordance between pathological and final diagnosis, sensitivity was 94.7% and specificity was 83.3%; positive and negative predictive value were 90.0% and 90.9%, respectively. Accuracy (diagnostic yield) of biopsy was 90.3%.

Conclusion

CT-guided percutaneous aortic and periaortic core needle biopsies are safe and efficacious procedures with high diagnostic yield.

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No funding was received to assist with the preparation of this manuscript.

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Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA

    Marika A. Pitot, Chris N. Gu, Daniel A. Adamo, Anil Nicholas Kurup, John J. Schmitz & Annie T. Packard

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  1. Marika A. Pitot
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  2. Chris N. Gu
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Correspondence to Marika A. Pitot.

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Pitot, M.A., Gu, C.N., Adamo, D.A. et al. Safety and accuracy of aortic and periaortic CT-guided percutaneous core needle biopsy. Abdom Radiol 48, 2148–2156 (2023). https://doi.org/10.1007/s00261-023-03867-4

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  • DOI: https://doi.org/10.1007/s00261-023-03867-4

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