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The psoas muscle density as a predictor of postoperative complications and 30-day mortality for acute mesenteric ischemia patients

  • Special Section: Intestinal Ischemia
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Objective

Low muscle mass and quality is associated with poor surgical outcomes. Psoas muscle density (PMD)is a validated surrogate for muscle quality that can be easily measured from a clinical computed tomography (CT) scan. The objective of this study was to investigate the association between PMD and short-term postoperative outcomes in patients with acute mesenteric ischemia (AMI).

Methods

From April 2006 and September 2019, the clinical data of all patients who underwent surgical intervention with a preoperative diagnosis of AMI and had preoperative non-contrast CT images available were retrospectively reviewed. PMD was measured by CT at the third lumbar vertebra. The lowest quartile of PMD for men and women in all patients was used as sex-specific cut-off values for low PMD. Univariate and multivariate analyses evaluating risk factors of postoperative complications and 30-day mortality were performed.

Results

The cohort consisted of 88 patients with a mean age of 58.8 ± 16.2 years, of whom 21 (23.9%) patients had low PMD based on the diagnostic cut-off values (40.5 HU for men and 28.4 HU for women), 35 (39.8%) patients developed complications within 30 days of the operation, and 10 (11.3%) patients died within 30 days of surgery. Low PMD patients had a higher risk of postoperative complications and 30-day mortality than patients without low PMD patients. In a multivariate analysis, low PMD and low psoas muscle area (PMA) were independent predictors of postoperative complications. However, only low PMD remained an independent risk factor for 30-day mortality.

Conclusions

Preoperative assessment of the PMD on CT can be a practical method for identifying AMI patients at risk for postoperative complications and 30-day mortality.

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Data Availability

We declared that materials described in the manuscript, including all relevant raw data, will be freely available to any scientist wishing to use them for non-commercial purposes, without breaching participant confidentiality.

Code availability

All softwares used during the study appear in the submitted article; No code was generated or used during the study.

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Author notes

  1. Shou-Liang Miao and Xiao-Ning Ye have participated equally to this work and should share “first authorship”.

  2. Xiang-Wu Zheng and Fan-Feng Chen have participated equally to this work and should share “corresponding authorship”.

Authors and Affiliations

  1. Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, 325015, Zhejiang, People’s Republic of China

    Shou-Liang Miao, Ting-Ting Lin & Xiang-Wu Zheng

  2. The First Clinical Medical Institute, Wenzhou Medical University, Wenzhou, Zhejiang, China

    Xiao-Ning Ye

  3. Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, 325015, Zhejiang, People’s Republic of China

    Yi-Hui Qiu, Jing-Yong Huang & Fan-Feng Chen

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Contributions

Study conception and design: F-FC, X-WZ, S-LM; Acquisition of data: T-TL, XNY; Analysis and interpretation of data: S-LM, Y-HQ; Drafting of manuscript: S-L; Critical revision of manuscript: F-FC, X-WZ.

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Correspondence to Xiang-Wu Zheng or Fan-Feng Chen.

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Miao, SL., Ye, XN., Lin, TT. et al. The psoas muscle density as a predictor of postoperative complications and 30-day mortality for acute mesenteric ischemia patients. Abdom Radiol 47, 1644–1653 (2022). https://doi.org/10.1007/s00261-020-02714-0

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