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Pancreatic retention cyst: multi-modality imaging findings and review of the literature

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Abstract

Purpose

To investigate the multi-modality imaging presentation of the pancreatic retention cyst (PRC) with pathologic correlation.

Methods

Imaging data including CT, MRI, endoscopic ultrasonography (EUS) and EUS guided fine needle aspiration (EUS-FNA), and endoscopic retrograde cholangiopancreatography (ERCP) in fifteen patients (five males and ten females; mean age, 44.5 years) with pathologically proven PRC were analyzed retrospectively, and imaging features were correlated with pathological findings.

Results

Sixteen PRCs of 15 patients were included in this study. The mean size of PRCs was 4.4 × 4.6 cm (range 0.5 × 0.6–8.1 × 10.1 cm). PRC were round (n = 11), oval (n = 2), or lobular (n = 3). Punctiform calcification of the wall on CT (n = 2), thin septa (n = 4), thin wall (n = 3), and dilation of upstream pancreatic duct (n = 6; mean diameter, 4.3 mm) were detected. Dilation of upstream pancreatic duct was smooth in five PRCs and irregular in one PRC with pancreatic duct with punctiform calcification. Communication of PRCs with pancreatic duct was seen in two patients (one on CT, one on ERCP). Pancreatic inflammation and neoplasm were detected in four and two patients, respectively.

Conclusions

PRC typically presents as a well-defined, round cystic lesion, and different associated pathologic conditions including pancreatic inflammation and neoplasm may be detected in some patients on the multi-modality imaging examinations. Smooth dilation of upstream pancreatic duct with uncommon communication to the cyst may be helpful for the differentiation. Combination of a variety of imaging modalities could contribute to improve the diagnosis.

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References

  1. Nardi GL, Lyon DC, Sheiner HJ, Bartlett MK (1969) Solitary occult retention cysts of the pancreas. N Engl J Med 280:11–15

    Article  PubMed  CAS  Google Scholar 

  2. Klöppel G (2000) Pseudocysts and other non-neoplastic cysts of the pancreas. Semin Diagn Pathol 17:7–15

    PubMed  Google Scholar 

  3. Mitchenere P, Scott J, George P (1981) Islet cell adenoma and retention cyst: a rare cause of acute pancreatitis. Br J Surg 68:443–444

    Article  PubMed  CAS  Google Scholar 

  4. Naehrlich L, Zapke M, Rupprecht T, Becker D (2005) Endoscopic cystogastrostomy of a pancreatic retention cyst in cystic fibrosis. J Pediatr Gastroenterol Nutr 41:477–478

    Article  PubMed  Google Scholar 

  5. Jani N, Bani Hani M, Schulick RD, Hruban RH, Cunningham SC (2011) Diagnosis and management of cystic lesions of the pancreas. Diagn Ther Endosc 2011:478913

    Article  PubMed  Google Scholar 

  6. Goh BK, Tan YM, Chung YF, et al. (2006) Non-neoplastic cystic and cystic-like lesions of the pancreas: may mimic pancreatic cystic neoplasms. ANZ J Surg 76:325–331

    Article  PubMed  Google Scholar 

  7. Molvar C, Kayhan A, Lakadamyali H, Oto A (2011) Nonneoplastic cystic lesions of pancreas: a practical clinical, histologic, and radiologic approach. Curr Probl Diagn Radiol 40:141–148

    Article  PubMed  Google Scholar 

  8. Mlika M, Farah F, Jarboui S, et al. (2009) A benign cystic mass of the pancreas mimicking a malignant lesion. Pathologica 101:261–262

    PubMed  CAS  Google Scholar 

  9. Gananadha S, Hunt DR (2005) A unique case of pancreatitis and retention cyst in esophageal heterotopic pancreas. Surg Laparosc Endosc Percutan Tech 15:345–347

    Article  PubMed  Google Scholar 

  10. Vogel JD, Yeo CJ (2003) Choledochal cyst or pancreatic (retention) cyst: a case report. J Gastrointest Surg 7:754–757

    Article  PubMed  Google Scholar 

  11. Morise Z, Yamafuji K, Tsuji T, et al. (2002) A giant retention cyst of the pancreas (cystic dilatation of dorsal pancreatic duct) associated with pancreas divisum. J Gastroenterol 37:1079–1082

    Article  PubMed  Google Scholar 

  12. Takahashi H, Miura Y, Yamada H, et al. (1997) A case of hemorrhagic retention cyst of the pancreas. Nippon Shokakibyo Gakkai Zasshi 94:792–797

    PubMed  CAS  Google Scholar 

  13. Nishihara K, Kawabata A, Ueno T, et al. (1996) The differential diagnosis of pancreatic cysts by MR imaging. Hepatogastroenterology 43:714–720

    PubMed  CAS  Google Scholar 

  14. Mera K, Tajiri H, Muto M, et al. (1999) Clinical significance of magnetic resonance cholangiopancreatography for the diagnosis of cystic tumor of the pancreas compared with endoscopic retrograde cholangiopancreatography and computed tomography. Jpn J Clin Oncol 29:294–298

    Article  PubMed  CAS  Google Scholar 

  15. Takahashi H, Miura Y, Yamada H, et al. (1997) A case of hemorrhagic retention cyst of the pancreas. Nippon Shokakibyo Gakkai Zasshi 94(11):792–797

    PubMed  CAS  Google Scholar 

  16. Iwase K, Takenaka H, Oshima S, et al. (1992) A case of pancreatic cyst containing gall sludge. Gastroenterol Jpn 27:550–553

    PubMed  CAS  Google Scholar 

  17. Toth IR, Lang JN (1986) Giant pancreatic retention cyst in cystic fibrosis: a case report. Pediatr Pathol 6:103–110

    Article  PubMed  CAS  Google Scholar 

  18. Stewart DL, Torma MJ, Meyer GW (1978) Pancreatic retention cyst secondary to chronic pancreatitis. A cause of hemobilia. Am J Dig Dis 23:663–666

    Article  PubMed  CAS  Google Scholar 

  19. Ikeda M, Sato T, Ochiai M, et al. (1993) Ultrasonographic follow-up study of small pancreatic cysts of unknown etiology. Bildgebung 60:209–214

    PubMed  CAS  Google Scholar 

  20. Loludice TA, Jarmolych J, Buhac I (1977) Pancreatic retention cyst. A cause of obstructive jaundice. J Am Med Assoc 238:889–890

    Article  CAS  Google Scholar 

  21. Kosmahl M, Pauser U, Anlauf M, Klöppel G (2005) Pancreatic ductal adenocarcinomas with cystic features: neither rare nor uniform. Mod Pathol 18:1157–1164

    Article  PubMed  Google Scholar 

  22. Gonoi W, Akai H, Hagiwara K, et al. (2011) Pancreas divisum as a predisposing factor for chronic and recurrent idiopathic pancreatitis: initial in vivo survey. Gut 60:1103–1108

    Article  PubMed  Google Scholar 

  23. Mosler P, Akisik F, Sandrasegaran K, et al. (2012) Accuracy of magnetic resonance cholangiopancreatography in the diagnosis of pancreas divisum. Dig Dis Sci 57:170–174

    Article  PubMed  Google Scholar 

  24. Brugge WR (2008) Management and outcomes of pancreatic cystic lesions. Dig Liver Dis 40:854–859

    Article  PubMed  CAS  Google Scholar 

  25. Oh HC, Kim MH, Hwang CY, et al. (2008) Cystic lesions of the pancreas: challenging issues in clinical practice. Am J Gastroenterol 103:229–239

    Article  PubMed  Google Scholar 

  26. Zhang J, Wang PJ, Yuan XD (2010) Correlation between CT patterns and pathological classification of intraductal papillary mucinous neoplasm. Eur J Radiol 73:96–101

    Article  PubMed  Google Scholar 

  27. Tran Cao HS, Kellogg B, Lowy AM, Bouvet M (2010) Cystic neoplasms of the pancreas. Surg Oncol Clin N Am 19(2):267–295

    Article  PubMed  Google Scholar 

  28. Shah AA, Sainani NI, Kambadakone AR, et al. (2009) Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma: radiologic–pathologic correlation. World J Gastroenterol 15:2739–2747

    Article  PubMed  Google Scholar 

  29. Sedlack R, Affi A, Vazquez-Sequeiros E, et al. (2002) Utility of EUS in the evaluation of cystic pancreatic lesions. Gastrointest Endosc 56:543–547

    Article  PubMed  Google Scholar 

  30. Frossard JL, Amouyal P, Amouyal G, et al. (2003) Performance of endosonography-guided fine needle aspiration and biopsy in the diagnosis of pancreatic cystic lesions. Am J Gastroenterol 98(7):1516–1524

    Article  PubMed  Google Scholar 

  31. Fritscher-Ravens A, Brand L, Knöfel WT, et al. (2002) Comparison of endoscopic ultrasound-guided fine needle aspiration for focal pancreatic lesions in patients with normal parenchyma and chronic pancreatitis. Am J Gastroenterol 97:2768–2775

    Article  PubMed  Google Scholar 

  32. Iordache S, Săftoiu A, Cazacu S, et al. (2008) Endoscopic ultrasound approach of pancreatic cancer in chronic pancreatitis patients in a tertiary referral centre. J Gastrointestin Liver Dis 17(3):279–284

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, General Hospital of Lanzhou PLA, No. 333 Bin He Road (South), Lanzhou, 730050, Ganshu, People’s Republic of China

    Fangyuan Ren, Gang Chen & Xiaodong Hao

  2. Department of Nuclear Medicine, Changhai Hospital, No. 174 Changhai Road, Shanghai, 200433, People’s Republic of China

    Fangyuan Ren, Changjing Zuo & Jianhua Wang

  3. Department of Radiology, Changhai Hospital, No. 174 Changhai Road, Shanghai, 200433, People’s Republic of China

    Changjing Zuo, Jianping Lu & Chengwei Shao

Authors
  1. Fangyuan Ren
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  2. Changjing Zuo
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  3. Gang Chen
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  4. Jianhua Wang
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  5. Jianping Lu
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  6. Chengwei Shao
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  7. Xiaodong Hao
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Corresponding author

Correspondence to Chengwei Shao.

Additional information

Fangyuan Ren and Changjing Zuo contributed equally to this study and should be considered co-first authors.

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Ren, F., Zuo, C., Chen, G. et al. Pancreatic retention cyst: multi-modality imaging findings and review of the literature. Abdom Imaging 38, 818–826 (2013). https://doi.org/10.1007/s00261-012-9976-1

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  • DOI: https://doi.org/10.1007/s00261-012-9976-1

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