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Unusual fatty metamorphosis observed in diffuse liver metastases of stage 4S neuroblastoma

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Abstract

We report a case of stage 4S neuroblastoma in which CT showed diffuse liver metastases containing a geographical fatty area in the periportal region. MRI showed this abnormality to correspond to an area with an unusual pattern of fatty change. 123I-metaiodobenzylguanidine (MIBG) scintigraphy demonstrated increased accumulation throughout the liver, except for the region showing fatty change. To the best of our knowledge, this is the first report of liver metastases from neuroblastoma with geographical fatty infiltration.

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Authors and Affiliations

  1. Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji Kamigyo-ku, Kyoto City, 602-8566, Japan

    Jun Tazoe, Chio Okuyama & Tsunehiko Nishimura

  2. Department of Paediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji Kamigyo-ku, Kyoto City, 602-8566, Japan

    Tomoko Iehara & Hajime Hosoi

Authors
  1. Jun Tazoe
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  2. Chio Okuyama
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  3. Tomoko Iehara
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  4. Hajime Hosoi
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  5. Tsunehiko Nishimura
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Correspondence to Jun Tazoe.

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Tazoe, J., Okuyama, C., Iehara, T. et al. Unusual fatty metamorphosis observed in diffuse liver metastases of stage 4S neuroblastoma. Pediatr Radiol 40, 777–780 (2010). https://doi.org/10.1007/s00247-009-1491-3

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  • DOI: https://doi.org/10.1007/s00247-009-1491-3

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