Abstract
This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.
References
Akcoral A, Oran B, Tavli V, Oren H, Cevik NT (1996) Transient right-sided hypertrophic cardiomyopathy in an infant born to a diabetic mother. Indian J Pediatr 63:700–703
Chen S-C (1998) Transient hypertrophic cardiomyopathy in neonates (letter to the editor). Pediatr Cardiol 19:371
Das BB (2010) Plasma B-type natriuretic peptides in children with cardiovascular disease. Pediatr Cardiol 31:1135–1145
Ko HK, Lee JH, Choi BM, Lee JH, Yoo KH, Son CS, Lee JW (2008) Utility of the rapid B-type natriuretic peptide assay for detection of cardiovascular problems in newborn infants with respiratory difficulties. Neonatology 94:16–21
Law YM, Hoyer AW, Reller MD, Silberbach M (2009) Accuracy of plasma B-type natriuretic peptide to diagnose significant cardiovascular disease in children. J Am Coll Cardiol 54:1467–1475
Manetti A, De simone L, Pollini I, Favilli S, Scarano E, Donzelli GP (1992) Transient ventricular septal hypertrophy in the first year of life associated with neonatal brain injury (letter to the editor). Pediatr Cardiol 13:63–64
Pascual-Figal DA, Domingo M, Casas T, Gich I, Ordonez-Llanos J, Martinez O, Cinca J, Valdes M, Januzzi JL, Bayes-Genis A (2008) Usefulness of clinical and NT-proBNP monitoring for prognostic guidance in destabilized heart failure outpatients. Eur Heart J 29:1011–1018
Smith J, Goetze JP, Andersen CB, Vejlstrup N (2010) Practical application of natriuretic peptides in paediatric cardiology. Cardiol Young 20:353–363
Tomar M, Radhakrishnan S, Shrivastava S (2003) Transient severe isolated right-ventricular hypertrophy in neonates. Cardiol Young 13:384–386
Vaillant MC, Chantepie A, Casasoprano A, Chamoboux C, Suc AL, Gold F, Laugier J (1997) Transient hypertrophic cardiomyopathy in neonates after acute fetal distress. Pediatric Cardiol 18:52–56
Acknowledgments
The authors appreciate the editorial assistance of Sophie Rushton-Smith, PhD, Publications Specialist for MedLink (http://www.medlink.org.uk), Technical Editor for the Archives of Cardiovascular Diseases, Senior Academic Fellow of the Thrombosis Research Institute, and Fellow of the Royal Society of Medicine.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
Video 1 Echocardiogram showing right-ventricle outlet tract obstruction. (MOV 1701 kb)
Rights and permissions
About this article
Cite this article
Yañez, J., Rodriguez, D., Treviño, C. et al. Stress Transient Hypertrophic Cardiomyopathy and B-Type Natriuretic Peptide Role. Pediatr Cardiol 34, 702–706 (2013). https://doi.org/10.1007/s00246-012-0317-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00246-012-0317-5