Skip to main content
Log in

Stress Transient Hypertrophic Cardiomyopathy and B-Type Natriuretic Peptide Role

  • Case Report
  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

Abstract

This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Akcoral A, Oran B, Tavli V, Oren H, Cevik NT (1996) Transient right-sided hypertrophic cardiomyopathy in an infant born to a diabetic mother. Indian J Pediatr 63:700–703

    Article  PubMed  CAS  Google Scholar 

  2. Chen S-C (1998) Transient hypertrophic cardiomyopathy in neonates (letter to the editor). Pediatr Cardiol 19:371

    Google Scholar 

  3. Das BB (2010) Plasma B-type natriuretic peptides in children with cardiovascular disease. Pediatr Cardiol 31:1135–1145

    Article  PubMed  Google Scholar 

  4. Ko HK, Lee JH, Choi BM, Lee JH, Yoo KH, Son CS, Lee JW (2008) Utility of the rapid B-type natriuretic peptide assay for detection of cardiovascular problems in newborn infants with respiratory difficulties. Neonatology 94:16–21

    Article  PubMed  CAS  Google Scholar 

  5. Law YM, Hoyer AW, Reller MD, Silberbach M (2009) Accuracy of plasma B-type natriuretic peptide to diagnose significant cardiovascular disease in children. J Am Coll Cardiol 54:1467–1475

    Article  PubMed  CAS  Google Scholar 

  6. Manetti A, De simone L, Pollini I, Favilli S, Scarano E, Donzelli GP (1992) Transient ventricular septal hypertrophy in the first year of life associated with neonatal brain injury (letter to the editor). Pediatr Cardiol 13:63–64

    PubMed  CAS  Google Scholar 

  7. Pascual-Figal DA, Domingo M, Casas T, Gich I, Ordonez-Llanos J, Martinez O, Cinca J, Valdes M, Januzzi JL, Bayes-Genis A (2008) Usefulness of clinical and NT-proBNP monitoring for prognostic guidance in destabilized heart failure outpatients. Eur Heart J 29:1011–1018

    Article  PubMed  CAS  Google Scholar 

  8. Smith J, Goetze JP, Andersen CB, Vejlstrup N (2010) Practical application of natriuretic peptides in paediatric cardiology. Cardiol Young 20:353–363

    Article  PubMed  Google Scholar 

  9. Tomar M, Radhakrishnan S, Shrivastava S (2003) Transient severe isolated right-ventricular hypertrophy in neonates. Cardiol Young 13:384–386

    PubMed  Google Scholar 

  10. Vaillant MC, Chantepie A, Casasoprano A, Chamoboux C, Suc AL, Gold F, Laugier J (1997) Transient hypertrophic cardiomyopathy in neonates after acute fetal distress. Pediatric Cardiol 18:52–56

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The authors appreciate the editorial assistance of Sophie Rushton-Smith, PhD, Publications Specialist for MedLink (http://www.medlink.org.uk), Technical Editor for the Archives of Cardiovascular Diseases, Senior Academic Fellow of the Thrombosis Research Institute, and Fellow of the Royal Society of Medicine.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carlos Jerjes-Sanchez.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Video 1 Echocardiogram showing right-ventricle outlet tract obstruction. (MOV 1701 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yañez, J., Rodriguez, D., Treviño, C. et al. Stress Transient Hypertrophic Cardiomyopathy and B-Type Natriuretic Peptide Role. Pediatr Cardiol 34, 702–706 (2013). https://doi.org/10.1007/s00246-012-0317-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00246-012-0317-5

Keywords

Navigation