Abstract
We report a case of anomalous origin of the left main coronary artery (LCA) from the noncoronary sinus of valsalva (LCANCS) in a young healthy patient who presented with syncope and cardiopulmonary arrest during exercise. The enhanced computed tomography showed acute angle take-off (AAT) of LCA, and the exercise stress thallium-201 myocardial scintigraphy demonstrated a large defect at the LCA perfusion region. We propose that the coexistence of AAT and resulting ischemia causes sudden cardiac death during exercise in the patients with LCANCS.
References
Catanzaro JN, Makaryus AN, Catanese C (2005) Sudden cardiac death associated with an extremely rare coronary anomaly of the left and right coronary arteries arising exclusively from the posterior (noncoronary) sinus of Valsalva. Clin Cardiol 28:542–544
Cohen DJ, Kim D, Baim DS (1991) Origin of the left main coronary artery from the “non-coronary” sinus of Valsalva. Cathet Cardiovasc Diagn 22:190–192
Datta J, White CS, Gilkeson RC, Meyer CA, Kansal S, Jani ML, Arildsen RC, Read K (2005) Anomalous coronary arteries in adults: depiction at multi-detector row CT angiography. Radiology 235:812–818
Frescura C, Basso C, Thiene G, Corrado D, Pennelli T, Angelini A, Daliento L (1998) Anomalous origin of coronary arteries and risk of sudden death: a study based on an autopsy population of congenital heart disease. Hum Pathol 29:689–695
Hamamichi Y, Okada E, Ichida F (2000) Anomalous origin of the main stem of the left coronary artery from the non-facing sinus of valsalva associated with sudden death in a young athlete. Cardiol Young 10:147–149
Ishikawa T, Otsuka T, Suzuki T (1990) Anomalous origin of the left main coronary artery from the noncoronary sinus of Valsalva. Pediatr Cardiol 11:173–174
Lawson MA, Dailey SM, Soto B (1993) Selective injection of a left coronary artery arising anomalously from the posterior aortic sinus. Cathet Cardiovasc Diagn 30:300–302
Lee JJ, Kim DH, Byun SS, Choi WG, Lee CW, Yi SM, Kwan J, Park KS, Lee WH (2009) A case of acute myocardial infarction with the anomalous origin of the right coronary artery from the ascending aorta above the left sinus of Valsalva and left coronary artery from the posterior sinus of Valsalva. Yonsei Med J 50:164–168
Liberman L, Pass RH, Kaufman S, Hordof AJ, Printz BF, Prakash A (2005) Left coronary artery arising from the non-coronary sinus: a rare congenital coronary anomaly. Pediatr Cardiol 26:672–674
Lo PH, Chang KC, Hung JS, Chen HL, Fang CY, Fu M, Wu CJ, Lau KW (1997) Anomalous origin of left main coronary artery from the noncoronary sinus: an intravascular ultrasound observation. Cathet Cardiovasc Diagn 42:430–433
Nathan M, Singh M, Lakdawala N, Bacha EA (2007) Anomalous left coronary artery from aorta with Prinzmetal’s angina: a postoperative dilemma successfully managed. Pediatr Cardiol 28:400–402
Virmani R, Chun PK, Goldstein RE, Robinowitz M, McAllister HA (1984) Acute takeoffs of the coronary arteries along the aortic wall and congenital coronary ostial valve-like ridges: association with sudden death. J Am Coll Cardiol 3:766–771
Yang S, Zeng MS, Zhang ZY, Ling ZQ, Ma JY, Chen G (2010) Sixty-four-multi-detector computed tomography diagnosis of coronary artery anomalies in 66 patients. Chin Med J 123:838–842
Zeina AR, Blinder J, Sharif D, Rosenschein U, Barmeir E (2009) Congenital coronary artery anomalies in adults: non-invasive assessment with multidetector CT. Br J Radiol 82:254–261
Acknowledgments
The authors thank Dr. Daisuke Tezuka, Department of Cardiovascular Medicine, Tokyo Medical and Dental University, and Dr. Akira Toriihara, Department of Diagnostic Radiology and Oncology, Tokyo Medical and Dental University, for their assistance with coronary imaging.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nishiyama, M., Doi, S., Matsumoto, A. et al. Exercise-Induced Myocardial Ischemia in a Case of Anomalous Origin of the Left Main Coronary Artery from the Noncoronary Sinus of Valsalva. Pediatr Cardiol 32, 1028–1031 (2011). https://doi.org/10.1007/s00246-011-0051-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00246-011-0051-4