Abstract
In adults, increased QT dispersion has been shown to predict arrhythmic risk as well as risk of sudden death in several clinical settings. It is controversial whether QT and JT dispersion are increased in children with ventricular ectopy and a structurally normal heart. We studied two groups of children: 25 patients with ventricular ectopy and 25 healthy children as controls. Standard electrocardiograms were reviewed and dispersions of both corrected QT (QTc) and JT (JTc) intervals were compared. We conclude that QTc and JTc dispersions are significantly increased in children with ventricular ectopy compared to control subjects.
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References
ME Alexander (2001) Ventricular arrhythmias in children and young adults. Cardiac arrhythmias in children and young adults with congenital heart disease. Lippincott Williams and Wilkins Philadelphia 201–234
CS Barr A Naas M Freeman et al. (1994) ArticleTitleQT dispersion and sudden unexpected death in chronic heart failure. Lancet 343 327–329 Occurrence Handle10.1016/S0140-6736(94)91164-9 Occurrence Handle1:STN:280:ByuC38rnvFQ%3D Occurrence Handle7905146
HC Bazett (1920) ArticleTitleAn analysis of time relations of electrocardiograms. Heart 7 353–370
CI Berul TL Sweeten AM Dubin MJ Shah VL Vetter (1994) ArticleTitleUse of the rate-corrected JT interval for prediction of repolarization abnormalities in children. Am J Cardiol 74 1254–1257 Occurrence Handle10.1016/0002-9149(94)90558-4 Occurrence Handle1:STN:280:ByqD28jmvFQ%3D Occurrence Handle7977100
G Buja M Miorelli P Turrini et al. (1993) ArticleTitleComparison of QT dispersion in hypertrophic cardiomyopathy between patients with and without ventricular arrhythmias and sudden death. Am J Cardiol 72 973–976 Occurrence Handle10.1016/0002-9149(93)91118-2 Occurrence Handle1:STN:280:ByuD38nnslM%3D Occurrence Handle8213559
A Dabrowski E Kramarz R Piotrowicz (1999) ArticleTitleDispersion of QT interval following ventricular premature beats and mortality after myocardial infarction. Cardiology 91 75–80 Occurrence Handle10.1159/000006883 Occurrence Handle1:STN:280:DyaK1MzotVSgtQ%3D%3D Occurrence Handle10449876
L Daliento F Caneve P Turrini et al. (1995) ArticleTitleClinical significance of high-frequency, low-amplitude electrocardiographic signals and QT dispersion in patients operated on tetralogy of Fallot. Am J Cardiol 76 408–411 Occurrence Handle10.1016/S0002-9149(99)80114-3 Occurrence Handle1:STN:280:ByqA28njvFM%3D Occurrence Handle7639173
CP Day JM McComb RW Campbell (1992) ArticleTitleQT dispersion in sinus beats and ventricular extra systoles in normal hearts. Br Heart J 67 39–41 Occurrence Handle1:STN:280:By2C2Mzltlw%3D Occurrence Handle1371221
GS Fu A Meissner R Simon (1997) ArticleTitleRepolarization dispersion and sudden cardiac death in patients with impaired left ventricular function. Eur Heart J 18 189–190 Occurrence Handle9043834
MA Gatzoulis JA Till AN Redington (1997) ArticleTitleDepolarization-repolarization inhomogeneity after repair of tetralogy of Fallot. The substrate for malignant ventricular tachycardia? Circulation 95 401–404 Occurrence Handle1:STN:280:ByiC287hvF0%3D Occurrence Handle9008456
J Jacobson A Garson PC Gillette DG McNamara (1978) ArticleTitlePremature ventricular contractions in normal children. J Pediatr 92 36–38 Occurrence Handle619077
L Kautzner M Malik (1997) ArticleTitleQT interval dispersion and its clinical utility. PACE 20 928–937
DE Miga CL Case PC Gillette (1996) ArticleTitleHigh prevalence of repolarization abnormalities in children with simple ventricular ectopy. Clin Cardiol 19 726–728 Occurrence Handle1:STN:280:ByiD38fpvVQ%3D Occurrence Handle8874992
SG Priori C Napolitano L Diehl et al. (1994) ArticleTitleDispersion of the QT interval. A marker of therapeutic efficacy in the idiopathic long QT syndrome. Circulation 89 1681–1689 Occurrence Handle1:STN:280:ByuC1Mbntlc%3D Occurrence Handle7908611
D Puljevic A Smalcelji Z Durakovic V Goldner (1997) ArticleTitleQT dispersion, daily variations, QT interval adaptation and late potentials as risk markers for ventricular tachycardia. Eur Heart J 18 1343–1349 Occurrence Handle1:STN:280:DyaK1c7itVSisA%3D%3D Occurrence Handle9458429
G Radjen D Raskovic S Kadijevic et al. (2000) ArticleTitleSignificance of QT dispersion in the onset of ventricular arrhythmia in patients with heart failure. Vojnosanit Pregl 57 39–47 Occurrence Handle1:STN:280:DC%2BD3c3pslCnug%3D%3D Occurrence Handle10838956
DM Roden R Lazzara M Rosen et al. (1996) ArticleTitleMultiple mechanisms in the long QT syndrome. Current knowledge, gaps, and future directions. Circulation 94 2929–2934
Acknowledgments
We are thankful to Dr. Michael Schaffer, Chief of Electrophysiology, Section of Pediatric Cardiology, The Children’s Hospital, Denver, CO, for critical review of the manuscript.
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Das, B., Sharma, J. Repolarization Abnormalities in Children with a Structurally Normal Heart and Ventricular Ectopy . Pediatr Cardiol 25, 354–356 (2004). https://doi.org/10.1007/s00246-003-0478-3
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DOI: https://doi.org/10.1007/s00246-003-0478-3