Abstract
X-ray phase-contrast imaging based on grating interferometry is a technique with the potential to provide absorption, differential phase contrast, and dark-field signals simultaneously. The multi-line X-ray source used recently in grating interferometry has the advantage of high-energy X-rays for imaging of thick samples for most clinical and industrial investigations. However, it has a drawback of limited field of view (FOV), because of the axial extension of the X-ray emission area. In this paper, we analyze the effects of axial extension of the multi-line X-ray source on the FOV and its improvement in terms of Fresnel diffraction theory. Computer simulation results show that the FOV limitation can be overcome by use of an alternative X-ray tube with a specially designed multi-step anode. The FOV of this newly designed X-ray source can be approximately four times larger than that of the multi-line X-ray source in the same emission area. This might be beneficial for the applications of X-ray phase contrast imaging in materials science, biology, medicine, and industry.
Similar content being viewed by others
References
Momose A, Fukuda J (1995) Med Phys 22:375–379
Fitzgerald R (2000) Phys Today 53:23–26
Lewis RA (2004) Phys Med Biol 49:3573–3583
Momose A (2005) Jpn J Appl Phys 44:6355–6367
Bonse U, Hart M (1965) Appl Phys Lett 6:155–156
Momose A, Takeda T, Itai Y, Hirano K (1996) Nat Med 2:473–475
Wilkins SW, Gureyev TE, Gao D, Pogany A, Stevenson AW (1996) Nature 384:335–338
Nugent KA, Gureyev TE, Cookson DF, Paganin D, Barnea Z (1996) Phys Rev Lett 77:2961–2964
Davis TJ, Gao D, Gureyev TE, Stevenson AW, Wilkins SW (1995) Nature 373:595–598
Chapman D, Thomlinson W, Johnston RE, Washburn D, Pisano E, Gmür N, Zhong Z, Menk R, Arfelli F, Sayers D (1997) Phys Med Biol 42:2015–2025
Zhu P, Yuan Q, Huang W, Shu H, Gao B, Hu T, Wu Z (2005) Appl Phys Lett 87:264101
David C, Nöhammer B, Solak HH, Ziegler E (2002) Appl Phys Lett 81:3287–3289
Momose A, Kawamoto S, Koyama I, Hamaishi Y, Takai K, Suzuki Y (2003) Jpn J Appl Phys 42:L866–L868
Momose A (2003) Opt Express 11:2303–2314
Weitkamp T, Diaz A, David C, Pfeiffer F, Stampanoni M, Cloetens P, Ziegler E (2005) Opt Express 13:6296–6304
Nesterets YI, Wilkins SW (2008) Opt Express 16:5849–5867
Pfeiffer F, Weitkamp T, Bunk O, David C (2006) Nat Phys 2:258–261
Weitkamp T, David C, Kottler C, Bunk O, Pfeiffer F (2006) Proc SPIE 6318:63180S
Kottler C, David C, Pfeiffer F, Bunk O (2007) Opt Express 15:1175–1181
Pfeiffer F, Kotter C, Bunk O, David C (2007) Phys Rev Lett 98:108105
Kottler C, Pfeiffer F, Bunk O, Grunzweig C, Bruder J, Kaufmann R, Tlustos L, Walt H, Briod I, Weitkamp T, David C (2007) Phys Stat Sol (A) 204(8):2728–2733
Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry E, Brönnimann CH, Grünzweig C, David C (2008) Nat Mater 7:134–137
Pfeiffer F, Bech M, Bunk O, Donath T, Henrich B, Kraft P, David C (2009) J Appl Phys 105:102006
David C, Bruder J, Rohbeck T, Grünzweig C, Kottler C, Diaz A, Bunk O, Pfeiffer F (2009) Microelectron Eng 84:1172–1177
Noda D, Tsujii H, Takahashi N, Hattori T (2010) Microsyst Technol 16:1309–1313
Niu H, Guo J, Wang K, Yang Q (2006) C.N. Patent No 200610062487.1
Momose A, Yashiro W, Kuwabara H, Kawabata K (2009) Jpn J Appl Phys 48:076512
Lei Y, Liu X, Guo J, Zhao Z, Niu H (2010) Chin Phys B 20:042901
Rutishauser S, Zanette I, Donath T, Sahlholm A, Linnros J, David C (2011) Appl Phys Lett 98:171107
Liu X, Lei Y, Zhao Z, Guo J, Niu H (2010) Acta Phys Sin 59:6927–6932
Thuering T, Modregger P, Grund T, Kenntner J, David C, Stampanoni M (2011) Appl Phys Lett 99:041111
Wang Z, Zhu P, Huang W, Yuan Q, Liu X, Zhang K, Hong Y, Zhang H, Ge X, Gao K, Wu Z (2010) Anal Bioanal Chem 397:2137–2141
Wang Z, Zhu P, Huang W, Yuan Q, Liu X, Zhang K, Hong Y, Zhang H, Ge X, Gao K, Wu Z (2010) Anal Bioanal Chem 397:2091–2094
Thüring T, Modregger P, Pinzer BR, Wang Z, Rutishauser S, David C, Grund T, Kenntner J, Stampanoni M (2011) Proc SPIE 7961:79611G
Du Y, Liu X, Lei Y, Guo J, Niu H (2011) Opt Express 19:22669–22674
Acknowledgements
This study was supported by the National Natural Science Foundation of China (grants 60532090, 61001184, and 61101175), and the Science and Technology Bureau of Shenzhen (grants JC201005280502A and CXB201005240011A).
Author information
Authors and Affiliations
Corresponding author
Additional information
Yang Du and Jianheng Huang contributed equally to this paper.
Rights and permissions
About this article
Cite this article
Du, Y., Huang, J., Lin, D. et al. Analysis of field of view limited by a multi-line X-ray source and its improvement for grating interferometry. Anal Bioanal Chem 404, 793–797 (2012). https://doi.org/10.1007/s00216-012-6178-1
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00216-012-6178-1