Skip to main content
Log in

Conditions of nisin production by Lactococcus lactis subsp. lactis and its main uses as a food preservative

  • Mini-Review
  • Published:
Archives of Microbiology Aims and scope Submit manuscript

Abstract

Nisin is a small peptide produced by Lactococcus lactis ssp lactis that is currently industrially produced. This preservative is often used for growth prevention of pathogenic bacteria contaminating the food products. However, the use of nisin as a food preservative is limited by its low production during fermentation. This low production is mainly attributed to the multitude of parameters influencing the fermentation progress such as bacterial cells activity, growth medium composition (namely carbon and nitrogen sources), pH, ionic strength, temperature, and aeration. This review article focuses on the main parameters that affect nisin production by Lactococcus lactis bacteria. Moreover, nisin applications as a food preservative and the main strategies generally used are also discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

Data availability

Data and materials are available from the corresponding author upon reasonable request.

Code availability

Not applicable.

References

Download references

Funding

Not applicable.

Author information

Authors and Affiliations

Authors

Contributions

All authors participated equally.

Corresponding author

Correspondence to Adem Gharsallaoui.

Ethics declarations

Conflict of interest

The authors declare no conflicts of interest associated with this manuscript.

Additional information

Communicated by Erko stackebrandt.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Khelissa, S., Chihib, NE. & Gharsallaoui, A. Conditions of nisin production by Lactococcus lactis subsp. lactis and its main uses as a food preservative. Arch Microbiol 203, 465–480 (2021). https://doi.org/10.1007/s00203-020-02054-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00203-020-02054-z

Keywords

Navigation