References
Bolland MJ, Barber PA, Doughty RN, Mason B, Horne A, Ames R et al (2008) Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial. Brit Med J 336:262–266
Reid IR, Bolland MJ, Grey A (2010) Does calcium supplementation increase cardiovascular risk? Clin Endocrinol 73:689–695
Bolland MJ, Avenell A, Baron JA, Grey A, MacLennan GS, Gamble GD et al (2010) Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. Brit Med J 341:c3691
Bolland MJ, Grey A, Avenell A, Gamble GD, Reid IR (2011) Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis. Brit Med J 342:d2040
Reid IR, Bolland MJ, Avenell A, Grey A (2011) Cardiovascular effects of calcium supplementation. Osteoporos Int 22:1649–1658. doi:10.1007/s00198-011-1599-9
Reid IR, Bolland MJ (2008) Calcium supplementation and vascular disease. Climacteric 11:280–286
Tang BM, Eslick GD, Nowson C, Smith C, Bensoussan A (2007) Use of calcium or calcium in combination with vitamin D supplementation to prevent fracture and bone loss in people aged 50 years and older: a meta-analysis. Lancet 370:657–666
The DIPART (vitamin D Individual Patient Analysis of Randomized Trials) Group (2010) Patient level pooled analysis of 68500 patients from seven major vitamin D fracture trials in US and Europe. Brit Med J 340:b5463
Reid IR, Mason B, Horne A et al (2006) Randomized controlled trial of calcium in healthy older women. Am J Med 119:777–785
Reid IR, Bolland MJ, Grey A (2008) Effect of calcium supplementation on hip fractures. Osteoporos Int 19:1119–1123
Cordoba G, Schwartz L, Woloshin S, Bae H, Gotzsche PC (2010) Definition, reporting, and interpretation of composite outcomes in clinical trials: systematic review. Brit Med J 341:c3920
Bolland MJ, Grey A, Reid IR (2010) “Cherry picking” did not occur in studied example. Brit Med J 341:c5009
Gotzsche PC, Cordoba G, Schwartz L, Woloshin S, Bae H (2010) Rapid response: the abstract was not transparent. Brit Med J Sept
Lewis JR, Calver J, Zhu K, Flicker L, Prince RL (2011) Response to ‘calcium supplements and cardiovascular risk’. J Bone Miner Res 26:900–901
Bolland MJ, Grey A, Reid IR (2011) Calcium supplements and cardiovascular risk. J Bone Miner Res 26:899, author reply 900–891
Lewis JR, Calver J, Zhu K, Flicker L, Prince RL (2011) Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up. J Bone Miner Res 26:35–41
Holman CD, Bass AJ, Rosman DL et al (2008) A decade of data linkage in Western Australia: strategic design, applications and benefits of the WA data linkage system. Aust Health Rev 32:766–777
Prince RL, Devine A, Dhaliwal SS, Dick IM (2006) Effects of calcium supplementation on clinical fracture and bone structure; results of a 5-year, double-blind, placebo-controlled trial in elderly women. Arch Intern Med 166:869–875
Nordin BEC, Lewis JR, Daly RM, Horowitz J, Metcalfe A, Lange K, Prince RL (2011) The calcium scare—what would Austin Bradford Hill have thought? Osteoporos Int. doi:10.1007/s00198-011-1680-4
Van Pelt N, Ruygrok P, Bolland MJ, Gamble GD, Mason B, Ames R, Reid IR (2009) Do calcium supplements lead to an increase in coronary calcification? Heart Lung Circ 18S:S1–S286. doi:10.1016/j.hlc.2009.05.596
Daly RM, Ebeling RP, Khan B, Nowson CA (2009) Effects of calcium-vitamin D3 fortified milk on abdominal aortic calcification in older men: retrospective analysis of a 2-year randomised controlled trial. J Bone Miner Res 24:S134
Author information
Authors and Affiliations
Corresponding author
Additional information
This is a response to the letter from Bolland et al. that can be found at doi 10.1007/s00198-011-1783-y.
Rights and permissions
About this article
Cite this article
Nordin, B.E.C., Lewis, J.R., Daly, R.M. et al. The calcium scare: response to Bolland et al.. Osteoporos Int 22, 3081–3083 (2011). https://doi.org/10.1007/s00198-011-1799-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00198-011-1799-3