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Comparative trends in hospitalizations for osteoporotic fractures and other frequent diseases between 2000 and 2008

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Abstract

Summary

In Switzerland, the number, incidence, and cost of acute hospitalizations for major osteoporotic fractures (MOF) and major cardiovascular events (MCE) increased in both women and men between 2000 and 2008, although the mean length of stay (LOS) was significantly reduced. Similar trend patterns were observed for hip fractures and strokes (decrease) and nonhip fractures and acute myocardial infarctions (increase).

Introduction

The purpose of this study was to compare the trends and epidemiological characteristics of hospitalizations for MOF and other frequent diseases between years 2000 and 2008 in Switzerland.

Methods

Trends in the number, age-standardized incidence, mean LOS, and cost of hospitalized MOF and MCE (acute myocardial infarction, stroke, and heart failure) were compared in women and men aged ≥45 years, based on data from the Swiss Federal Statistical Office.

Results

Between 2000 and 2008, the incidence of acute hospitalizations for MOF increased by 3.4% in women and 0.3% in men. In both sexes, a significant decrease in hip fractures (−15.0% and −11.0%) was compensated by a concomitant, significant increase in nonhip fractures (+24.8% and +13.8%). Similarly, the incidence of acute hospitalizations for MCE increased by 4.4% in women and 8.2% in men, as an aggregated result from significantly increasing acute myocardial infarctions and significantly decreasing strokes. While the mean LOS in the acute inpatient setting decreased almost linearly between years 2000 and 2008 in all indications, the inpatient costs increased significantly (p < 0.001) for MOF (+30.1% and +42.7%) and MCE (+22.6% and +47.1%) in women and men, respectively.

Conclusions

Between years 2000 and 2008, the burden of hospitalized osteoporotic fractures to the Swiss healthcare system has continued to increase in both sexes. In women, this burden was significantly higher than that of MCE and the gap widened over time.

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Acknowledgements

This work was supported by an unrestricted research grant from MSD Switzerland AG. The sponsor had no influence on the design, analysis, or interpretation of the data. We are grateful to Dr. Philippe Kress, Kressmed, Glattbrugg, Switzerland for his contribution to data analysis and his critical review of the manuscript.

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, CH-3010, Bern, Switzerland

    K. Lippuner, S. Grifone, A. W. Popp, C. Senn & R. Perrelet

  2. Institute of Pharmaceutical Medicine/ECPM, University of Basel, Basel, Switzerland

    M. Schwenkglenks

  3. Institute of Social and Preventive Medicine, Bern, Switzerland

    M. Schwenkglenks

  4. Swiss Federal Statistical Office, Neuchâtel, Switzerland

    P. Schwab

Authors
  1. K. Lippuner
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  2. S. Grifone
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  3. M. Schwenkglenks
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  4. P. Schwab
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  5. A. W. Popp
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  6. C. Senn
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  7. R. Perrelet
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Correspondence to K. Lippuner.

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Lippuner, K., Grifone, S., Schwenkglenks, M. et al. Comparative trends in hospitalizations for osteoporotic fractures and other frequent diseases between 2000 and 2008. Osteoporos Int 23, 829–839 (2012). https://doi.org/10.1007/s00198-011-1660-8

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  • DOI: https://doi.org/10.1007/s00198-011-1660-8

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