Abstract
Purpose
The purpose of this study was to compare patients with osteochondral lesions of the talus (OCLT) with and without concomitant chronic ankle instability (CAI).
Methods
Data from the German Cartilage Registry (KnorpelRegister DGOU) for 63 patients with a solitary OCLT were used. All patients received autologous matrix-induced chondrogenesis (AMIC) for OCLT treatment. Patients in group A received an additional ankle stabilisation, while patients in group B received AMIC alone. Both groups were compared according to demographic, lesion-related, and therapy-related factors as well as baseline clinical outcome scores at the time of surgery. The Foot and Ankle Ability Measure (FAAM), the Foot and Ankle Outcome Score (FAOS), and the Numeric Rating Scale for Pain (NRS) were used.
Results
Patients in group A were older compared to group B [median 34 years (range 20–65 years) vs. 28.5 years (range 18–72 years)]; the rate of trauma-associated OCLTs was higher (89.7% vs. 38.3%); more patients in group A had a previous non-surgical treatment (74.1% vs. 41.4%); and their OCLT lesion size was smaller [median 100 mm2 (range 15–600 mm2) vs. 150 mm2 (range 25–448 mm2)]. Most OCLTs were located medially in the coronary plane and centrally in the sagittal plane in both groups. Patients in group A had worse scores on the FAOS quality-of-life subscale compared to patients in group B.
Conclusion
Patients with OCLT with concomitant CAI differ from those without concomitant CAI according to demographic and lesion-related factors. The additional presence of CAI worsens the quality of life of patients with OCLT. Patients with OCLT should be examined for concomitant CAI, so that if CAI is present, it can be integrated into the treatment concept.
Level of evidence
IV.
Similar content being viewed by others
Abbreviations
- AMIC:
-
Autologous matrix-induced chondrogenesis
- AOFAS:
-
American Orthopedic Foot and Ankle Society
- BHL:
-
Berndt–Harty–Loomer
- CAI:
-
Chronic ankle instability
- FAAM:
-
Foot and Ankle Ability Measure
- FAOS:
-
Foot and Ankle Outcome Score
- ICRS:
-
International Cartilage Repair Society
- IRB:
-
Institutional Review Board
- NRS:
-
Numeric Rating Scale for Pain
- OCLA:
-
Osteochondral lesion of the ankle
- OCLT:
-
Osteochondral lesion of the talus
References
Becher C, Malahias MA, Ali MM, Maffulli N, Thermann H (2019) Arthroscopic microfracture vs arthroscopic autologous matrix-induced chondrogenesis for the treatment of articular cartilage defects of the talus. Knee Surg Sports Traumatol Arthrosc 27(9):2731–2736
Choi WJ, Lee JW, Han SH, Kim BS, Lee SK (2008) Chronic lateral ankle instability: the effect of intra-articular lesions on clinical outcome. Am J Sports Med 36(11):2167–2172
D’Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG (2017) Combining microfractures, autologous bone graft, and autologous matrix-induced chondrogenesis for the treatment of juvenile osteochondral talar lesions. Foot ankle Int 38(5):485–495
Gottschalk O, Altenberger S, Baumbach S, Kriegelstein S, Dreyer F, Mehlhorn A, Horterer H, Topfer A, Roser A, Walther M (2017) Functional medium-term results after autologous matrix-induced chondrogenesis for osteochondral lesions of the talus: a 5-year prospective cohort study. J Foot Ankle Surg 56(5):930–936
Gregush RV, Ferkel RD (2010) Treatment of the unstable ankle with an osteochondral lesion: results and long-term follow-up. Am J Sports Med 38(4):782–790
Hawker GA, Mian S, Kendzerska T, French M (2011) Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP). Arthritis Care Res (Hoboken) 63(Suppl 1):240–252
Hintermann B, Boss A, Schäfer D (2002) Arthroscopic findings in patients with chronic ankle instability. Am J Sports Med 30(3):402–409
Jiang D, Ao Y-F, Jiao C, Xie X, Chen L-X, Guo Q-W, Hu Y-L (2018) Concurrent arthroscopic osteochondral lesion treatment and lateral ankle ligament repair has no substantial effect on the outcome of chronic lateral ankle instability. Knee Surg Sports Traumatol Arthrosc 26(10):3129–3134
Kim S-W, Jung H-G, Lee J-S (2020) Ligament stabilization improved clinical and radiographic outcomes for individuals with chronic ankle instability and medial ankle osteoarthritis. Knee Surg Sports Traumatol Arthrosc. https://doi.org/10.1007/s00167-020-05845-5
Komenda GA, Ferkel RD (1999) Arthroscopic findings associated with the unstable ankle. Foot Ankle Int 20(11):708–713
Lee J, Hamilton G, Ford L (2011) Associated intra-articular ankle pathologies in patients with chronic lateral ankle instability: arthroscopic findings at the time of lateral ankle reconstruction. Foot Ankle Spec 4(5):284–289
Lee M, Kwon JW, Choi WJ, Lee JW (2015) Comparison of outcomes for osteochondral lesions of the talus with and without chronic lateral ankle instability. Foot Ankle Int 36(9):1050–1057
Li H, Hua Y, Li H, Li S, Ma K, Chen S (2018) Treatment of talus osteochondral defects in chronic lateral unstable ankles: small-sized lateral chondral lesions had good clinical outcomes. Knee Surg Sports Traumatol Arthrosc 26(7):2116–2122
Loomer R, Fisher C, Lloyd-Smith R, Sisler J, Cooney T (1993) Osteochondral lesions of the talus. Am J Sports Med 21(1):13–19
Mehl J, Otto A, Willinger L, Hapfelmeier A, Imhoff AB, Niemeyer P, Angele P, Zinser W, Spahn G, Schmitt A (2019) Degenerative isolated cartilage defects of the patellofemoral joint are associated with more severe symptoms compared to trauma-related defects: results of the German Cartilage Registry (KnorpelRegister DGOU). Knee Surg Sports Traumatol Arthrosc 27(2):580–589
Nauck T, Lohrer H (2011) Translation, cross-cultural adaption and validation of the German version of the Foot and Ankle Ability Measure for patients with chronic ankle instability. Br J Sports Med 45(10):785–790
O’Loughlin PF, Heyworth BE, Kennedy JG (2010) Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle. Am J Sports Med 38(2):392–404
Okuda R, Kinoshita M, Morikawa J, Yasuda T, Abe M (2005) Arthroscopic findings in chronic lateral ankle instability: do focal chondral lesions influence the results of ligament reconstruction? Am J Sports Med 33(1):35–42
van Rijn RM, van Os AG, Bernsen RMD, Luijsterburg PA, Koes BW, Bierma-Zeinstra SMA (2008) What is the clinical course of acute ankle sprains? A systematic literature review. Am J Med 121(4):324–331.e6
Shimozono Y, Yasui Y, Ross AW, Miyamoto W, Kennedy JG (2017) Scaffolds based therapy for osteochondral lesions of the talus: a systematic review. World J Orthop 8(10):798–808
Taga I, Shino K, Inoue M, Nakata K, Maeda A, Henry JH (1993) Articular cartilage lesions in ankles with lateral ligament injury. An arthroscopic study. Am J Sports Med 21(1):120–127
Usuelli FG, D’Ambrosi R, Maccario C, Boga M, de Girolamo L (2018) All-arthroscopic AMIC (AT-AMIC) technique with autologous bone graft for talar osteochondral defects: clinical and radiological results. Knee Surg Sports Traumatol Arthrosc 26(3):875–881
Usuelli FG, de Girolamo L, Grassi M, D’Ambrosi R, Montrasio UA, Boga M (2015) All-arthroscopic autologous matrix-induced chondrogenesis for the treatment of osteochondral lesions of the talus. Arthrosc Tech 4(3):e255–259
Valderrabano V, Miska M, Leumann A, Wiewiorski M (2013) Reconstruction of osteochondral lesions of the talus with autologous spongiosa grafts and autologous matrix-induced chondrogenesis. Am J Sports Med 41(3):519–527
Van Bergen CJA, Sierevelt IN, Hoogervorst P, Waizy H, van Dijk CN, Becher C (2014) Translation and validation of the German version of the foot and ankle outcome score. Arch Orthop Trauma Surg 134(7):897–901
Van den Borne MPJ, Raijmakers NJH, Vanlauwe J, Victor J, de Jong SN, Bellemans J, Saris DBF (2007) International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture. Osteoarthr Cartil 15(12):1397–1402
Van Dijk CN, Bossuyt PM, Marti RK (1996) Medial ankle pain after lateral ligament rupture. J Bone Joint Surg Br 78(4):562–567
Wiewiorski M, Barg A, Valderrabano V (2013) Autologous matrix-induced chondrogenesis in osteochondral lesions of the talus. Foot Ankle Clin 18(1):151–158
Yasui Y, Takao M, Miyamoto W, Matsushita T (2014) Simultaneous surgery for chronic lateral ankle instability accompanied by only subchondral bone lesion of talus. Arch Orthop Trauma Surg 134(6):821–827
Acknowledgments
We want to thank the Deutsche Arthrose-Hilfe e.V. and the Stiftung Oskar-Helene-Heim.
Funding
The German Cartilage Registry is financially supported by the Deutsche Arthrose-Hilfe e.V. and the Stiftung Oskar-Helene-Heim.
Author information
Authors and Affiliations
Contributions
DK: study design, data acquisition, statistical data analysis and interpretation, drafting and writing the manuscript. AA, MA, SS and CB: study design, revision of the manuscript. MW, OG, YB, SE and CP data acquisition, revision of the manuscript. MDA: study design, statistical data analysis and interpretation, drafting and writing the manuscript. All authors read and approved the final manuscript.
Corresponding author
Ethics declarations
Conflict of interest
CP is a consultant of Medartis AG. CP has received or will receive research grants not related to this paper from Plasmaconcept, Medartis, Stryker, DePuysSynthes, NewDeal, and OPED. The other authors declare that they have no potential conflict of interest.
Ethical approval
The study was performed according to the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Körner, D., Ateschrang, A., Schröter, S. et al. Concomitant ankle instability has a negative impact on the quality of life in patients with osteochondral lesions of the talus: data from the German Cartilage Registry (KnorpelRegister DGOU). Knee Surg Sports Traumatol Arthrosc 28, 3339–3346 (2020). https://doi.org/10.1007/s00167-020-05954-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00167-020-05954-1