References
Brusselaers N, Hoste EA, Monstrey S, Colpaert KE, De Waele JJ, Vandewoude KH, Blot SI (2005) Outcome and changes over time in survival following severe burns from 1985 to 2004. Int Care Med 31:1648–1653. doi:10.1007/s00134-010-1861-1
Asensio MJ, Sánchez M, Galván B, Herrero E, Cachafeiro L, Agrifoglio A, Perales E, Luque S, García-de-Lorenzo A (2014) Concentrations of micafungin 100 mg daily in plasma and burn eschares in critically ill patients with severe burn injuries. In: 27th Annual Congress of the European Society of Intensive Care Medicine, Barcelona, Spain, September 27–October 1
Sasaki J, Yamanouchi S, Kudo D, Endo T, Nomura R, Takuma K, Kushimoto S, Shinozawa Y, Kishino S, Hori S, Aikawa N (2012) Micafungin concentrations in the plasma and burn eschar of severely burned patients. Antimicrob Agents Chemother 56:1113–1115. doi:10.1128/AAC.05381-11
Jullien V, Blanchet B, Benyamina M, Tod M, Vinsonneau C (2012) Pharmacokinetics of caspofungin in two patients with burn injuries. Antimicrob Agents Chemother 56:4550–4551. doi:10.1128/AAC.00039-12
Han S, Kim J, Yim H, Hur J, Song W, Lee J, Jeon S, Hong T, Woo H, Yim DS (2013) Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infection. Antimicrob Agents Chemother 57:1006–1011. doi:10.1128/AAC.01372-12
Acknowledgments
This work was supported in part by a grant from Astellas Pharma S.A. (Madrid, Spain).
Conflicts of interest
A.G. has received fees from Astellas Pharma for participation in an expert meeting. A.A. has received travel grants from Astellas Pharma (Madrid, Spain) for ECCMID 2013 and Spanish National Mycology Congress attendance. S.L. has received travel grants from Astellas Pharma (Madrid, Spain) for ECCMID 2014 attendance. All other authors have no conflict of interest to declare.
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Asensio, M.J., Sánchez, M., Galván, B. et al. Micafungin at a standard dosage of 100 mg/day achieves adequate plasma exposure in critically ill patients with severe burn injuries. Intensive Care Med 41, 371–372 (2015). https://doi.org/10.1007/s00134-014-3586-z
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DOI: https://doi.org/10.1007/s00134-014-3586-z