Skip to main content
Log in

Micafungin at a standard dosage of 100 mg/day achieves adequate plasma exposure in critically ill patients with severe burn injuries

  • Letter
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Brusselaers N, Hoste EA, Monstrey S, Colpaert KE, De Waele JJ, Vandewoude KH, Blot SI (2005) Outcome and changes over time in survival following severe burns from 1985 to 2004. Int Care Med 31:1648–1653. doi:10.1007/s00134-010-1861-1

    Article  Google Scholar 

  2. Asensio MJ, Sánchez M, Galván B, Herrero E, Cachafeiro L, Agrifoglio A, Perales E, Luque S, García-de-Lorenzo A (2014) Concentrations of micafungin 100 mg daily in plasma and burn eschares in critically ill patients with severe burn injuries. In: 27th Annual Congress of the European Society of Intensive Care Medicine, Barcelona, Spain, September 27–October 1

  3. Sasaki J, Yamanouchi S, Kudo D, Endo T, Nomura R, Takuma K, Kushimoto S, Shinozawa Y, Kishino S, Hori S, Aikawa N (2012) Micafungin concentrations in the plasma and burn eschar of severely burned patients. Antimicrob Agents Chemother 56:1113–1115. doi:10.1128/AAC.05381-11

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Jullien V, Blanchet B, Benyamina M, Tod M, Vinsonneau C (2012) Pharmacokinetics of caspofungin in two patients with burn injuries. Antimicrob Agents Chemother 56:4550–4551. doi:10.1128/AAC.00039-12

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  5. Han S, Kim J, Yim H, Hur J, Song W, Lee J, Jeon S, Hong T, Woo H, Yim DS (2013) Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infection. Antimicrob Agents Chemother 57:1006–1011. doi:10.1128/AAC.01372-12

    Article  CAS  PubMed Central  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported in part by a grant from Astellas Pharma S.A. (Madrid, Spain).

Conflicts of interest

A.G. has received fees from Astellas Pharma for participation in an expert meeting. A.A. has received travel grants from Astellas Pharma (Madrid, Spain) for ECCMID 2013 and Spanish National Mycology Congress attendance. S.L. has received travel grants from Astellas Pharma (Madrid, Spain) for ECCMID 2014 attendance. All other authors have no conflict of interest to declare.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Luque.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Asensio, M.J., Sánchez, M., Galván, B. et al. Micafungin at a standard dosage of 100 mg/day achieves adequate plasma exposure in critically ill patients with severe burn injuries. Intensive Care Med 41, 371–372 (2015). https://doi.org/10.1007/s00134-014-3586-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-014-3586-z

Keywords

Navigation