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Does immunonutrition in patients with sepsis do more harm than good?

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References

  1. Heyland DK, Novak F, Drover J, Jain M, Suchner U (2001) Should immunonutrition become routine in critically ill patients: a systematic review of the evidence. JAMA 286:944–953

    Article  CAS  Google Scholar 

  2. Bower RH, Cerra FB, Bershadsky B, Licari JJ, Hoyt DB, Jensen GL, et al (1995) Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized, clinical trial. Crit Care Med 23:436–449

    Article  CAS  Google Scholar 

  3. Dent DL, Heyland DK, Levy H, Martindale R, Tayek J, Schloerb P, Kelley MJ (2003) Immunonutrition may increase mortality in critically ill patients with pneumonia: results of a randomized trial. Crit Care Med 30:A17

    Article  Google Scholar 

  4. Galban C, Montejo JC, Mesejo A, et al (2000) An immune-enhancing enteral diet reduces mortality rate and episodes of bacteremia in septic intensive care unit patients. Crit Care Med 28:643–648

    Article  CAS  Google Scholar 

  5. Heyland DK, MacDonald S, Keefe L, Drover JW (1998) Total parenteral nutrition in the critically ill patient: a meta-analysis. JAMA 280:2013–2019

    Article  CAS  Google Scholar 

  6. Basttistella FD, Widergren JT, Anderson JT, et al (1997) A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition. J Trauma 43:52–58

    Article  Google Scholar 

  7. Bruins MJ, Soeters PB, Larners WH, Meijer AJ, Deutz NEP (2002) L-Arginine supplementation in hyperdynamic endotoxemic pigs: effect on nitric oxide synthesis by different organs. Crit Care Med 30:508–517

    Article  CAS  Google Scholar 

  8. Suchner U, Heyland DK, Peter K (2002) Immune-modulating actions of arginine in the critically ill. Br J Nutr 87[Suppl 1]:S121–132

  9. Heyland DK (2002) Immunonutrition in the critically ill patient: putting the cart before the horse? Nutr Clin Pract17:267–272

    Google Scholar 

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Correspondence to Daren K. Heyland.

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Heyland, D.K., Samis, A. Does immunonutrition in patients with sepsis do more harm than good?. Intensive Care Med 29, 669–671 (2003). https://doi.org/10.1007/s00134-003-1710-6

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