Skip to main content

Advertisement

Log in

Socioeconomic inequalities and Black/White disparities in US cocaine-involved overdose mortality risk

  • Original Paper
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

Purpose

This study examined whether socioeconomic inequalities account for Black/White disparities in: (a) the prevalence of potential risk factors for overdose among adults using cocaine; and (b) national mortality rates for cocaine-involved overdose.

Methods

Data from 2162 Non-Hispanic (NH) Black or White adults (26 +) who reported past-year cocaine use in the 2015–2019 National Survey of Drug Use and Health were analyzed to obtain predicted probabilities of potential overdose risk factors by race and sex, using marginal effects via regression analyses, adjusting for age and socioeconomic indicators. Next, National Center for Health Statistics data (for 47,184 NH Black or White adults [26 +] who died of cocaine-involved overdose between 2015 and 2019) were used to calculate cocaine-involved overdose mortality rates by race and sex across age and educational levels.

Results

Several potential overdose vulnerabilities were disproportionately observed among NH Black adults who reported past-year cocaine use: poor/fair overall health; cocaine use disorder; more days of cocaine use yearly; hypertension (for women); and arrests (for men). Adjusting for age and socioeconomic indicators attenuated or eliminated many of these racial differences, although predicted days of cocaine use per year (for men) and cocaine use disorder (for women) remained higher in NH Black than White adults. Cocaine-involved overdose mortality rates were highest in the lowest educational strata of both races; nonetheless, Black/White disparities were observed even at the highest level of education, especially for adults ages 50 + .

Conclusion

Age and socioeconomic characteristics may account for some, yet not all, of Black/White disparities in vulnerability to cocaine-involved overdose.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Centers for Disease Control and Prevention (2022) CDC WONDER. Multiple cause of death. https://wonder.cdc.gov/mcd-icd10.html. Accessed 21 Jan 2022

  2. Hedegaard H, Miniño AM, Warner M (2020) Drug overdose deaths in the United States, 1999–2019: NCHS Data Brief 394. US Department of Health & Human Services

  3. Galea S, Ahern J, Tardiff K, Leon A, Coffin PO, Derr K, Vlahov D (2003) Racial/ethnic disparities in overdose mortality trends in New York City, 1990–1998. J Urban Health 80(2):201–211. https://doi.org/10.1093/jurban/jtg023

    Article  PubMed  PubMed Central  Google Scholar 

  4. Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS (2018) Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016. Science 361(6408):eaau1184. https://doi.org/10.1126/science.aau1184

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kariisa M, Scholl L, Wilson N, Seth P, Hoots B (2019) Drug overdose deaths involving cocaine and psychostimulants with abuse potential—United States, 2003–2017. MMWR Morb Mortal Wkly Rep 68(17):388–395. https://doi.org/10.15585/mmwr.mm6817a3

    Article  PubMed  PubMed Central  Google Scholar 

  6. Shiels MS, Freedman ND, Thomas D, Berrington de Gonzalez A (2018) Trends in U.S. drug overdose deaths in Non-Hispanic Black, Hispanic, and Non-Hispanic White persons, 2000–2015. Ann Intern Med 168(6):453–455. https://doi.org/10.7326/M17-1812

    Article  PubMed  Google Scholar 

  7. Cano M, Oh S, Salas-Wright CP, Vaughn MG (2020) Cocaine use and overdose mortality in the United States: evidence from two national data sources, 2002–2018. Drug Alcohol Depend 214:108148. https://doi.org/10.1016/j.drugalcdep.2020.108148

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Zinberg NE (1984) Drug, set, and setting: The basis for controlled intoxicant use. Yale University Press

  9. Phelan JC, Link BG (2015) Is racism a fundamental cause of inequalities in health? Ann Rev Sociol 41:311–330. https://doi.org/10.1146/annurev-soc-073014-112305

    Article  Google Scholar 

  10. Williams DR (1997) Race and health: basic questions, emerging directions. Ann Epidemiol 7(5):322–333. https://doi.org/10.1016/s1047-2797(97)00051-3

    Article  CAS  PubMed  Google Scholar 

  11. Miech R (2008) The formation of a socioeconomic health disparity: the case of cocaine use during the 1980s and 1990s. J Health Soc Behav 49(3):352–366. https://doi.org/10.1177/002214650804900308

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lillie-Blanton M, Anthony JC, Schuster CR (1993) Probing the meaning of racial/ethnic group comparisons in crack cocaine smoking. JAMA 269(8):993–997

    Article  CAS  Google Scholar 

  13. Palamar JJ, Davies S, Ompad DC, Cleland CM, Weitzman M (2015) Powder cocaine and crack use in the United States: an examination of risk for arrest and socioeconomic disparities in use. Drug Alcohol Depend 149:108–116. https://doi.org/10.1016/j.drugalcdep.2015.01.029

    Article  PubMed  PubMed Central  Google Scholar 

  14. Chen K, Kandel D (2002) Relationship between extent of cocaine use and dependence among adolescents and adults in the United States. Drug Alcohol Depend 68(1):65–85. https://doi.org/10.1016/s0376-8716(02)00086-8

    Article  PubMed  Google Scholar 

  15. John WS, Wu LT (2017) Trends and correlates of cocaine use and cocaine use disorder in the United States from 2011 to 2015. Drug Alcohol Depend 180:376–384. https://doi.org/10.1016/j.drugalcdep.2017.08.031

    Article  PubMed  PubMed Central  Google Scholar 

  16. O’Brien MS, Anthony JC (2005) Risk of becoming cocaine dependent: epidemiological estimates for the United States, 2000–2001. Neuropsychopharmacology 30(5):1006–1018. https://doi.org/10.1038/sj.npp.1300681

    Article  PubMed  Google Scholar 

  17. Galea S, Nandi A, Coffin PO, Tracy M, Markham Piper T, Ompad D, Vlahov D (2006) Heroin and cocaine dependence and the risk of accidental non-fatal drug overdose. J Addict Dis 25(3):79–87. https://doi.org/10.1300/J069v25n03_10

    Article  PubMed  Google Scholar 

  18. Kaye S, Darke S (2004) Non-fatal cocaine overdose among injecting and non-injecting cocaine users in Sydney. Australia Addiction 99(10):1315–1322. https://doi.org/10.1111/j.1360-0443.2004.00875.x

    Article  PubMed  Google Scholar 

  19. Han BH, Tuazon E, Kunins HV, Mantha S, Paone D (2019) Unintentional drug overdose deaths involving cocaine among middle-aged and older adults in New York City. Drug Alcohol Depend 198:121–125. https://doi.org/10.1016/j.drugalcdep.2019.01.042

    Article  PubMed  PubMed Central  Google Scholar 

  20. Ciccarone D (2017) Fentanyl in the US heroin supply: a rapidly changing risk environment. Int J Drug Policy 46:107–111. https://doi.org/10.1016/j.drugpo.2017.06.010

    Article  PubMed  PubMed Central  Google Scholar 

  21. McCall Jones C, Baldwin GT, Compton WM (2017) Recent increases in cocaine-related overdose deaths and the role of opioids. Am J Public Health 107(3):430–432. https://doi.org/10.2105/AJPH.2016.303627

    Article  PubMed  PubMed Central  Google Scholar 

  22. Hoots B, Vivolo-Kantor A, Seth P (2020) The rise in non-fatal and fatal overdoses involving stimulants with and without opioids in the United States. Addiction 115(5):946–958. https://doi.org/10.1111/add.14878

    Article  PubMed  Google Scholar 

  23. Cano M (2021) Racial/ethnic differences in US drug overdose mortality, 2017–2018. Addict Behav 112:106625. https://doi.org/10.1016/j.addbeh.2020.106625

    Article  PubMed  Google Scholar 

  24. Kariisa M, Seth P, Scholl L, Wilson N, Davis NL (2021) Drug overdose deaths involving cocaine and psychostimulants with abuse potential among racial and ethnic groups–United States, 2004–2019. Drug Alcohol Depend 227:109001. https://doi.org/10.1016/j.drugalcdep.2021.109001

    Article  PubMed  Google Scholar 

  25. Chen CY, Anthony JC (2004) Epidemiological estimates of risk in the process of becoming dependent upon cocaine: cocaine hydrochloride powder versus crack cocaine. Psychopharmacology 172(1):78–86. https://doi.org/10.1007/s00213-003-1624-6

    Article  CAS  PubMed  Google Scholar 

  26. Barry D, Sullivan B, Petry NM (2009) Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients. Psychol Addict Behav 23(1):168–174. https://doi.org/10.1037/a0014575

    Article  PubMed  PubMed Central  Google Scholar 

  27. Braun BL, Murray D, Hannan P, Sidney S, Le C (1996) Cocaine use and characteristics of young adult users from 1987 to 1992: the CARDIA Study. Coronary artery risk development in young adults. Am J Public Health 86(12):1736–1741. https://doi.org/10.2105/ajph.86.12.1736

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Falck RS, Wang J, Siegal HA, Carlson RG (2004) The prevalence of psychiatric disorder among a community sample of crack cocaine users: an exploratory study with practical implications. J Nerv Ment Dis 192(7):503–507. https://doi.org/10.1097/01.nmd.0000131913.94916.d5

    Article  PubMed  Google Scholar 

  29. Pope SK, Falck RS, Carlson RG, Leukefeld C, Booth BM (2011) Characteristics of rural crack and powder cocaine use: gender and other correlates. Am J Drug Alcohol Abuse 37(6):491–496. https://doi.org/10.3109/00952990.2011.600380

    Article  PubMed  PubMed Central  Google Scholar 

  30. Palamar JJ, Ompad DC (2014) Demographic and socioeconomic correlates of powder cocaine and crack use among high school seniors in the United States. Am J Drug Alcohol Abuse 40(1):37–43. https://doi.org/10.3109/00952990.2013.838961

    Article  PubMed  Google Scholar 

  31. Petry NM (2003) A comparison of African American and non-Hispanic Caucasian cocaine-abusing outpatients. Drug Alcohol Depend 69(1):43–49. https://doi.org/10.1016/s0376-8716(02)00255-7

    Article  PubMed  Google Scholar 

  32. Zapolski TC, Baldwin P, Lejuez CW (2016) Examining risk for frequent cocaine use: focus on an African American treatment population. Subst Use Misuse 51(7):882–891. https://doi.org/10.3109/10826084.2016.1155618

    Article  PubMed  PubMed Central  Google Scholar 

  33. Miguel AQC, Jordan A, Kiluk BD, Nich C, Babuscio TA, Mari JJ, Carroll KM (2019) Sociodemographic and clinical outcome differences among individuals seeking treatment for cocaine use disorders. The intersection of gender and race. J Subst Abuse Treat 106:65–72. https://doi.org/10.1016/j.jsat.2019.08.014

    Article  PubMed  PubMed Central  Google Scholar 

  34. Kerridge BT, Chou SP, Pickering RP, Ruan WJ, Huang B, Jung J, Zhang H, Fan AZ, Saha TD, Grant BF, Hasin DS (2019) Changes in the prevalence and correlates of cocaine use and cocaine use disorder in the United States, 2001–2002 and 2012–2013. Addict Behav 90:250–257. https://doi.org/10.1016/j.addbeh.2018.11.005

    Article  PubMed  Google Scholar 

  35. Mustaquim D, Jones CM, Compton WM (2021) Trends and correlates of cocaine use among adults in the United States, 2006–2019. Addict Behav 120:106950. https://doi.org/10.1016/j.addbeh.2021.106950

    Article  PubMed  Google Scholar 

  36. Nicholson HL Jr, Ford JA (2019) Sociodemographic, neighborhood, psychosocial, and substance use correlates of cocaine use among Black adults: findings from a pooled analysis of national data. Addict Behav 88:182–186. https://doi.org/10.1016/j.addbeh.2018.08.042

    Article  PubMed  Google Scholar 

  37. McHugh RK, Votaw VR, Sugarman DE, Greenfield SF (2018) Sex and gender differences in substance use disorders. Clin Psychol Rev 66:12–23. https://doi.org/10.1016/j.cpr.2017.10.012

    Article  PubMed  Google Scholar 

  38. Substance Abuse and Mental Health Services Administration (2019) Key substance use and mental health indicators in the United States: Results from the 2018 National Survey on Drug Use and Health (HHS Publication No. PEP19–5068, NSDUH Series H-54). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration

  39. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc B 57(1):289–300

    Google Scholar 

  40. Arias E, Heron M, Hakes J (2016) The validity of race and Hispanic-origin reporting on death certificates in the United States: an update 172: 1–21

  41. Ruggles S, Flood S, Foster S, Goeken R, Pacas J, Schouweiler M, Sobek M (2021) IPUMS USA: Version 11.0 . Minneapolis, MN: IPUMS. https://doi.org/10.18128/D010.V11.0

  42. Consonni D, Coviello E, Buzzoni C, Mensi C (2012) A command to calculate age-standardized rates with efficient interval estimation. Stata J 12(4):688–701

    Article  Google Scholar 

  43. Klein RJ, Schoenborn CA (2001). Age adjustment using the 2000 projected U.S. population. Healthy People statistical notes. no 20. National Center for Health Statistics

  44. Moore LD, Elkavich A (2008) Who’s using and who’s doing time: incarceration, the war on drugs, and public health. Am J Public Health 98(9 Suppl):S176–S180. https://doi.org/10.2105/ajph.98.supplement_1.s176

    Article  PubMed  PubMed Central  Google Scholar 

  45. Victor G, Zettner C, Huynh P, Ray B, Sightes E (2021) Jail and overdose: Assessing the community impact of incarceration on overdose. Addiction. https://doi.org/10.1111/add.15640

    Article  PubMed  Google Scholar 

  46. Williams RA (2009) Cardiovascular disease in African American women: a health care disparities issue. J Natl Med Assoc 101(6):536–540. https://doi.org/10.1016/s0027-9684(15)30938-x

    Article  PubMed  Google Scholar 

  47. Chen K, Scheier LM, Kandel DB (1996) Effects of chronic cocaine use on physical health: a prospective study in a general population sample. Drug Alcohol Depend 43(1–2):23–37. https://doi.org/10.1016/s0376-8716(96)01285-9

    Article  CAS  PubMed  Google Scholar 

  48. Schwartz BG, Rezkalla S, Kloner RA (2010) Cardiovascular effects of cocaine. Circulation 122(24):2558–2569. https://doi.org/10.1161/CIRCULATIONAHA.110.940569

    Article  PubMed  Google Scholar 

  49. Clark AM, DesMeules M, Luo W, Duncan AS, Wielgosz A (2009) Socioeconomic status and cardiovascular disease: risks and implications for care. Nat Rev Cardiol 6(11):712–722. https://doi.org/10.1038/nrcardio.2009.163

    Article  PubMed  Google Scholar 

  50. Ruttenber AJ, Sweeney PA, Mendlein JM, Wetli CV (1991) Preliminary findings of an epidemiologic study of cocaine-related deaths, Dade County, Florida, 1978–85. Natl Inst Drug Abuse Res Monogr Ser 110:95–111

    CAS  Google Scholar 

  51. Pottieger AE, Tressell PA, Inciardi JA, Rosales TA (1992) Cocaine use patterns and overdose. J Psychoactive Drugs 24(4):399–410. https://doi.org/10.1080/02791072.1992.10471664

    Article  CAS  PubMed  Google Scholar 

  52. Armenian P, Whitman JD, Badea A, Johnson W, Drake C, Dhillon SS, Rivera M, Brandehoff N, Lynch KL (2019) Notes from the field: unintentional fentanyl overdoses among persons who thought they were snorting cocaine - Fresno, California, January 7. MMWR Morb Mortal Wkly Rep 68(31):687–688. https://doi.org/10.15585/mmwr.mm6831a2

    Article  PubMed  PubMed Central  Google Scholar 

  53. Khatri UG, Viner K, Perrone J (2018) Lethal fentanyl and cocaine intoxication. N Engl J Med 379(18):1782. https://doi.org/10.1056/NEJMc1809521

    Article  PubMed  Google Scholar 

  54. Park JN, Rashidi E, Foti K, Zoorob M, Sherman S, Alexander GC (2021) Fentanyl and fentanyl analogs in the illicit stimulant supply: results from US drug seizure data, 2011–2016. Drug Alcohol Depend 218:108416. https://doi.org/10.1016/j.drugalcdep.2020.108416

    Article  CAS  PubMed  Google Scholar 

  55. Ho JY (2017) The contribution of drug overdose to educational gradients in life expectancy in the United States, 1992–2011. Demography 54(3):1175–1202. https://doi.org/10.1007/s13524-017-0565-3

    Article  PubMed  Google Scholar 

  56. Miech RA, Chilcoat H, Harder VS (2005) The increase in the association of education and cocaine use over the 1980s and 1990s: evidence for a “historical period” effect. Drug Alcohol Depend 79(3):311–320. https://doi.org/10.1016/j.drugalcdep.2005.01.022

    Article  PubMed  Google Scholar 

  57. Assari S, Lankarani MM (2016) Race and urbanity alter the protective effect of education but not income on mortality. Front Public Health 4:100. https://doi.org/10.3389/fpubh.2016.00100

    Article  PubMed  PubMed Central  Google Scholar 

  58. Assari S, Mistry R (2018) Educational attainment and smoking status in a national sample of american adults; evidence for the Blacks’ diminished return. Int J Environ Res Public Health 15(4):763. https://doi.org/10.3390/ijerph15040763

    Article  PubMed Central  Google Scholar 

  59. Farmer MM, Ferraro KF (2005) Are racial disparities in health conditional on socioeconomic status? Soc Sci Med 60(1):191–204. https://doi.org/10.1016/j.socscimed.2004.04.026

    Article  PubMed  Google Scholar 

  60. Assari S (2018) Health disparities due to diminished return among Black Americans: public policy solutions. Soc Issues Policy Rev 12(1):112–145. https://doi.org/10.1111/sipr.12042

    Article  Google Scholar 

  61. Williams DR, Mohammed SA (2013) Racism and health I: pathways and scientific evidence. Am Behav Sci 57(8):1152–1173. https://doi.org/10.1177/0002764213487340

    Article  Google Scholar 

  62. Federal Bureau of Prisons (2020) Inmate race. https://www.bop.gov/about/statistics/statistics_inmate_race.jsp. Accessed 1 Aug 2021

  63. Henry M, Watt R, Mahathey A, Ouellette J, Sitler A, Abt Associates (2020) The 2019 Annual Homeless Assessment Report (AHAR) to Congress. U.S. Department of Housing and Urban Development

  64. Reuter P, Caulkins JP, Midgette G (2021) Heroin use cannot be measured adequately with a general population survey. Addiction 116(10):2600–2609. https://doi.org/10.1111/add.15458

    Article  PubMed  Google Scholar 

  65. Latimore AD, Bergstein RS (2017) “Caught with a body” yet protected by law? Calling 911 for opioid overdose in the context of the Good Samaritan Law. Int J Drug Policy 50:82–89. https://doi.org/10.1016/j.drugpo.2017.09.010

    Article  PubMed  Google Scholar 

  66. Rostron BL, Boies JL, Arias E (2010) Education reporting and classification on death certificates in the United States. Vital Health Stat 2(151):1–21

    Google Scholar 

  67. Boslett AJ, Denham A, Hill EL, Adams MCB (2019) Unclassified drug overdose deaths in the opioid crisis: emerging patterns of inequity. J Am Med Inform Assoc 26(8–9):767–777. https://doi.org/10.1093/jamia/ocz050

    Article  PubMed  PubMed Central  Google Scholar 

  68. Horon IL, Singal P, Fowler DR, Sharfstein JM (2018) Standard death certificates versus enhanced surveillance to identify heroin overdose–related deaths. Am J Public Health 108(6):777–781. https://doi.org/10.2105/AJPH.2018.304385

    Article  PubMed  PubMed Central  Google Scholar 

  69. Lynch M, Omori M (2018) Crack as proxy: aggressive federal drug prosecutions and the production of black–white racial inequality. Law Soc Rev 52(3):773–809. https://doi.org/10.1111/lasr.12348

    Article  Google Scholar 

Download references

Funding

This work was supported by the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health [Award Number K01AA026645; PI: Christopher P. Salas-Wright]. The content is solely the responsibility of the authors and does not necessarily represent the official views of NIAAA or the NIH.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Manuel Cano.

Ethics declarations

Conflict of interest

The authors report no conflict of interest.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (PDF 244 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cano, M., Salas-Wright, C.P., Oh, S. et al. Socioeconomic inequalities and Black/White disparities in US cocaine-involved overdose mortality risk. Soc Psychiatry Psychiatr Epidemiol 57, 2023–2035 (2022). https://doi.org/10.1007/s00127-022-02255-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00127-022-02255-5

Keywords