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Schwangerschaft unter Immunsuppression

Pregnancy under immunosuppression

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Zusammenfassung

Kinderwunsch und Schwangerschaft sind bei immunsupprimierten Patientinnen wichtige Themen mit hohem Beratungs- und Betreuungsbedarf, nicht nur in spezialisierten Ambulanzen für Transplantationsmedizin sondern im Falle chronisch-entzündlicher Erkrankungen auch in allen Bereichen der Inneren Medizin. In dieser Übersicht werden die Risiken häufig eingesetzter Immunsuppressiva hinsichtlich der Schwangerschaft betrachtet. Als Entscheidungsgrundlage ist die Kenntnis spezifischer Risiken der jeweiligen Immunsuppressiva wesentlich, um die Therapie in Hinsicht auf die Grunderkrankung und die Schwangerschaft unter Berücksichtigung des Sicherheitsbedürfnisses der Patientinnen abzustimmen. Grundsätzlich sollte eine enge gemeinsame Betreuung durch den behandelnden Arzt und einen Gynäkologen erfolgen.

Abstract

The desire to have children and pregnancy itself are important topics in the treatment of patients under immunosuppression. In this review the risks of frequently prescribed immunosuppressants are discussed regarding the safety of mother and child during and after pregnancy. Knowledge of the specific risks of immunosuppressants in pregnancy is important to balance the therapy between the patients’ desire to be treated most effectively and to deliver a healthy child after an uncomplicated pregnancy. Generally, an interdisciplinary approach is advisable in treating and counseling immunosuppressed patients with a desire to have children and during pregnancy.

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  1. Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Halle, Ernst-Grube-Straße 40, 06120, Halle, Deutschland

    J. Walldorf , M.M. Dollinger & T. Seufferlein

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  1. J. Walldorf
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  2. M.M. Dollinger
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  3. T. Seufferlein
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Correspondence to J. Walldorf .

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Walldorf , J., Dollinger, M. & Seufferlein, T. Schwangerschaft unter Immunsuppression. Internist 52, 1178–1184 (2011). https://doi.org/10.1007/s00108-011-2822-7

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