Zusammenfassung
Es wird über einen 42-jährigen Patienten mit einer nekrotisierenden Fasziitis am rechten Bein berichtet. In mehreren tiefen Wundabstrichen gelang der Nachweis eines multiresistenten Acinetobacter-baumanii-Stammes. Die Therapie mit Imipenem und Tobramycin sowie ausgedehnte Nekrektomien führten zu einer langsamen Besserung der Symptomatik. Acinetobacter baumannii kommt zunehmend Bedeutung als Erreger nosokomialer Infektionen, insbesondere auf Intensivstationen, zu.
Abstract
A 42-year-old man developed necrotizing fasciitis on the right leg. A multidrug-resistant Acinetobacter baumannii was cultivated from the deep wound. Following therapy with imipenem and tobramycin as well as extensive debridement, the lesions improved slowly. A. baumannii is today an important cause of nosocomial infections, especially in intensive care units.
Literatur
Siegrist HH (2000) Acinetobacter spp. Nosokomiale Infektionen, Epidemiologie und Antibiotikaresistenz. Swiss-NOSO 7:6–7
Andrew P (2008) Molecular basis of acinetobacter virulence and pathogenicity. In: Gerischer U (Hrsg) Acinetobacter molecular biology. Caister Academic
Centers for Disease Control and Prevention (2004) Acinetobacter baumannii infections among patients at military medical facilities treating injured U.S. service members, 2002–2004. Morb Mortal Wkly Rep 53:1063–1066
Cisneros JM, Reyes MJ, Pachón J et al (1996) Bacteremia due to acinetobacter baumannii: epidemiology, clinical findings and prognostic features. Clin Infect Dis 22:1026–1032
Forster DH, Daschner FD (1998) Acinetobacter species as nosocomial pathogens. Eur J Clin Microbiol Infect Dis 17:73–77
Bergogne-Bérézin E, Towner KJ (1996) Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev 9:148–165
Rahal J (2006) Novel antibiotic combinations against infections with almost completely resistant pseudomonas aeruginosa and acinetobacter species. Clin Infect Dis 43(Suppl 2):S95–S99
Coelho JM, Turton JF, Kaufmann ME et al (2006) Occurrence of carbapenem-resistant acinetobacter baumannii clones at multiple hospitals in London and Southeast England. J Clin Microbiol 40:3623–3627
Karageorgopoulos DE, Falagas ME (2008) Current control and treatment of multidrug-resistant acinetobacter baumannii infections. Lancet Infect Dis 8:751–762
Bassetti M, Righi E, Esposito S et al (2008) Drug treatment for multidrug-resistant acinetobacter baumannii infections. Future Microbiol 3:649–660
Hillert R (2009) Polymyxine. In: Ackermann G (Hrsg) Antibiotika und Antimykotika. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, S 150–153
Gounden R, Bamford C, Zyl-Smit R van et al (2009) Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant acinetobacter baumannii infections. BMC Infect Dis 9(9):26
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wagner, J., Nenoff, P., Handrick, W. et al. Nekrotisierende Fasziitis durch Acinetobacter baumannii . Hautarzt 62, 128–130 (2011). https://doi.org/10.1007/s00105-010-1962-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00105-010-1962-3