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Structural constraints and neutrality in RNA

  • Molecular Modeling
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Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1278))

Abstract

Generic properties of neutral networks of RNA secondary structures can be described by means of random graph theory. The success of this approach is dependent on details of the underlying secondary structure. Some of these dependencies are analyzed in this paper. In addition we present an algorithm, which, given a network does conform to the random graph model, allows to determine whether it is a connected graph. The algorithm is linear in time in the sequence length, this being possible because of local connectivity, a special property of graphs under the random graph model.

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Correspondence to Christian V. Forst .

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Ralf Hofestädt Thomas Lengauer Markus Löffler Dietmar Schomburg

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© 1997 Springer-Verlag Berlin Heidelberg

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Göbel, U., Forst, C.V., Schuster, P. (1997). Structural constraints and neutrality in RNA. In: Hofestädt, R., Lengauer, T., Löffler, M., Schomburg, D. (eds) Bioinformatics. GCB 1996. Lecture Notes in Computer Science, vol 1278. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0033214

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  • DOI: https://doi.org/10.1007/BFb0033214

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-63370-9

  • Online ISBN: 978-3-540-69524-0

  • eBook Packages: Springer Book Archive

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