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Recent developments in the large scale cultivation of animal cells in monolayers

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Advances in Biochemical Engineering, Volume 14

Part of the book series: Advances in Biochemical Engineering ((ABE,volume 14))

Abstract

The history of monolayer cell culture is reviewed and the potential product applications for cells grown in this way outlined. Recent developments in understanding the basic components of this system and the way in which cells interact with the surface on which they grow are considered. The general features of the different types of equipment which have the potential of producing such cells on the industrial scale are reviewed. A discussion of the particular equipment types follows and leads to the conclusions that no one system has yet been perfected and that most potential for development resides in the glass sphere packed beds and/or microcarrier systems.

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  1. Animal Virus Research Institute Pirbright, Woking, Surrey, England

    Raymond E. Spier

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© 1980 Springer-Verlag

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Spier, R.E. (1980). Recent developments in the large scale cultivation of animal cells in monolayers. In: Advances in Biochemical Engineering, Volume 14. Advances in Biochemical Engineering, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0007191

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  • DOI: https://doi.org/10.1007/BFb0007191

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