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Determination of eight elements in six human cancer cell lines and two human normal cell lines by PIXE

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Abstract

Gastric, hepatic, and pulmonary cancer cell lines, and the third passage of normal gastric and pulmonary cell lines were analyzed by proton induced X-ray emission (PIXE) method. The contents of element Sr, Ca, Fe, Zn, P, K, Cu, and As in the cell lines were determined. The Sr, Ca, Fe, Zn, and As contents in cancer cell lines were significantly lower than those in the normal cell lines (p<0.05), whereas there were no significant differences for the P, K, and Cu contents (p>0.1). The results suggest that the need of some essential elements has been diminished in cancer cell proliferation.

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References

  1. M. M. Molokhia and Hamilton Smith,Arch. Environ. Health,15, 745 (1967).

    PubMed  CAS  Google Scholar 

  2. S. L. Rizk and H. H. Sky-Peck,Cancer Res. 44, 5390 (1984).

    PubMed  CAS  Google Scholar 

  3. M. K. Schwartz,Cancer Res. 35, 3481 (1975).

    PubMed  CAS  Google Scholar 

  4. Kuixiong Shi, Wufong Chang, and Xongxan Xu,Tumor 8(2), 71 (1988).

    Google Scholar 

  5. Qiang Chen; unpublished results.

  6. I. L. Cameron, N. K. R. Smith, T. B. Pool, and R. L. SparksCancer Res. 40, 1493 (1980).

    PubMed  CAS  Google Scholar 

  7. Minqian Li, Konglong Sheng, and Pokang Chin,Nucl. Instr. Methods 181, 37 (1981).

    Article  CAS  Google Scholar 

  8. M. R. C. Banyard and R. L. Tellam,Br. J. Cancer 51, 761 (1985).

    PubMed  CAS  Google Scholar 

  9. A. L. Boynton, L. P. Kleine, J. F. Whitfield, and Donatella Bossi,Exp. Cell Res. 160, 197 (1985).

    Article  PubMed  CAS  Google Scholar 

  10. P. S. Rudland and Helga Durbin,Biochem. Biophys. Res. Commun. 75, 556 (1977).

    Article  PubMed  CAS  Google Scholar 

  11. J. A. Fernandex-Pol,Cell,14, 489 (1978).

    Article  Google Scholar 

  12. J. W. Larrick and Peter Cresswell,J. Supramol. Struct. 11, 579 (1979).

    Article  PubMed  CAS  Google Scholar 

  13. R. J. Shamberger,Trace Element Anal. Chem. Med. Biol. 4, 181 (1987).

    Google Scholar 

  14. S. H. Chao, Yasuhiro Suzuki J. R. Zysk, and W. Y. Cheung,Mol. Pharmacol. 26, 75 (1984).

    PubMed  CAS  Google Scholar 

  15. R. Yarom, T. A. Hall, and Aaron Polliack,Proc. Natl. Acad. Sci. USA 73, 3690 (1976).

    Article  PubMed  CAS  Google Scholar 

  16. Peter Csermely and Janos Somogyi,Carcinogenesis 8, 1663 (1987).

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 800204, 201800, Shanghai, PRC

    Yongpeng Tong, Yongping Zhang, Yaoliang Xu, Jingyi Rui & Minqian Li

  2. Shanghai Cancer Institute, Shanghai, PRC

    Cuiying Shen, Zhongming Xiao & Jinxin Hong

Authors
  1. Yongpeng Tong
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  2. Yongping Zhang
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  3. Yaoliang Xu
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  4. Jingyi Rui
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  5. Minqian Li
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  6. Cuiying Shen
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  7. Zhongming Xiao
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  8. Jinxin Hong
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Tong, Y., Zhang, Y., Xu, Y. et al. Determination of eight elements in six human cancer cell lines and two human normal cell lines by PIXE. Biol Trace Elem Res 29, 31–34 (1991). https://doi.org/10.1007/BF03032671

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  • DOI: https://doi.org/10.1007/BF03032671

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