Summary
The effects of acid-base changes on cardiac output during diethyl ether anaesthesia were studied in 25 mongrel dogs prepared by surgically implanting a plastic encased non-ferrous core electromagnetic probe on the ascending aorta. The findings are:
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(1)
Metabolic acidaemia produced only slight decrease in cardiac output but a more marked fall became evident with decreasing pH.
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(2)
Respiratory acidaemia led to a slight rise in cardiac output.
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(3)
Respiratory alkalaemia decreased cardiac output.
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(4)
Metabolic alkalaemia also produced a decline in cardiac output.
Résumé
Les auteurs ont étudié les effets sur le débit cardiaque des modifications de l’équilibre acide-base au cours de l’anesthésie à l’éther chez 25 chiens. On avait préalablement procédé chez ces chiens a une implantation chirurgicale d’une sonde électromagneétique à noyau non-ferreux, placé sur l’aorte ascendante.
Les resultats obtenus ont été:
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1.
L’acidénie métabolique ne produit qu’une légère diminution du débit cardiaque, mais une baisse plus importante se manifeste avec un pH plus abaissé.
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2.
L’acidénie respiratoire provoque un légère augmentation du débit cardiaque.
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3.
L’alcalémie respiratoire abaisse le débit cardiaque.
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4.
L’alcalémie méabolique produit également une diminution du débit cardiaque.
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References
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This work was carried out at the University of Toronto, Anaesthesia Research Laboratory at St. Michael’s Hospital, Toranto.
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Sodipo, J.O., Lee, DC. & Morris, L.E. Cardiac output response to altered acid-base status during diethyl ether anaesthesia. Canad. Anaesth. Soc. J. 22, 673–679 (1975). https://doi.org/10.1007/BF03013315
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DOI: https://doi.org/10.1007/BF03013315