Skip to main content
Log in

Positivity of extrapulmonary Ga-67 uptake in sarcoidosis: Thyroid uptake due to chronic thyroiditis and bone uptake due to fibrous dysplasia

  • Case Reports
  • Published:
Annals of Nuclear Medicine Aims and scope Submit manuscript

Abstract

Ga-67 citrate scintigraphy was performed on a 29-year-old man who had been diagnosed as having pulmonary sarcoidosis by a transbronchial lung biopsy. A Ga-67 citrate scintigram showed increased uptake not only in the pulmonary hilum and mediastinum, but also in the thyroid gland and the right ilium. Chronic thyroiditis was confirmed by aspiration biopsy of the thyroid gland, and fibrous dysplasia was confirmed by CT guided biopsy of the right ilium. Extrapulmonary Ga-67 uptake in patients with sarcoidosis does not necessarily indicate the involvement of other tissues and organs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Sulavik SB, Palestro CJ, Spencer RP, Swyer AJ, Goldsmith SJ, Tierstein AS. Extrapulmonary sites of radiogallium accumulation in sarcoidosis.Clin Nucl Med 1990; 15: 876–878.

    Article  PubMed  CAS  Google Scholar 

  2. Sulavik SB, Spencer RP, Weed DA, Shapiro HR, Shiue ST, Castriotta RJ. Recognition of distinctive patterns of gallium-67 distribution in sarcoidosis.J Nucl Med 1990; 31: 1909–1914.

    PubMed  CAS  Google Scholar 

  3. Mayock RL, Bertrand P, Morrison CE, Scott JH. Manifestations of sarcoidosis. Analysis of 145 patients, with a review of nine series selected from literature.Am J Med 35: 67, 1963.

    Article  PubMed  CAS  Google Scholar 

  4. Wiesenhutter GW, Sharma OP. Is sarcoidosis an autoimmune disorder?: report of four cases and review of literature.Semin Arthritis Rheum 1979; 9: 124–144.

    Article  PubMed  CAS  Google Scholar 

  5. Hanock BW, Millard LG. Sarcoidosis and thyrotoxicosis. A study of five patients.Br J Dis Chest 1976; 70: 129–133.

    Article  Google Scholar 

  6. Nakamura H, Genma R, Mikami T, et al. High incidence of positive autoantibodies against thyroid peroxidase and thyroglobulin in patients with sarcoidosis.Clin Endocrinol 1997; 46: 467–472.

    Article  CAS  Google Scholar 

  7. Papadopoulos KI, Hornblad Y, Liljebladh H, Hallengren B. High frequency of endocrine autoimmunity in patients with sarcoidosis.Eur J Endocrinol 1996; 134: 331–336.

    PubMed  CAS  Google Scholar 

  8. Neville E, Carstairs LS, James DG. Sarcoidosis of bone.Q J Med 1977; 46: 215–217.

    PubMed  CAS  Google Scholar 

  9. Sartoris DJ, Resnick D, Resnick C, Yaghmai I. Musculoskeletal manifestations of sarcoidosis.Semin Roentgenol 1985; 20: 376–386.

    Article  PubMed  CAS  Google Scholar 

  10. Hoshi H, Dadparvar S, Slizofski WJ, Brown S, Glab LB, Brady LW. Bone and gallium scintigraphy in a patient with bone sarcoidosis.Radiat Med 1989; 7: 178–180.

    PubMed  CAS  Google Scholar 

  11. Gibson MJ, Middlemiss JH. Fibrous dysplasia of bone.Br J Radiol 1971; 44: 1–37.

    Article  PubMed  CAS  Google Scholar 

  12. Machida K, Makita K, Nishikawa J, et al. Scintigraphic manifestation of fibrous dysplasia.Clin Nucl Med 1986; 11: 426–429.

    Article  PubMed  CAS  Google Scholar 

  13. Greagh MF, Nunan TO. Positive gallium-67 citrate uptake in a patient with polyostotic fibrous dysplasia.Clin Nucl Med 1988; 13: 241–242.

    Article  Google Scholar 

  14. Hoshi H, Futami S, Ohnishi T, Nagamachi S, Jinnouchi S, Murai N, et al. Gallium-67 uptake in fibrous dysplasia of the bone.Ann Nucl Med 1990; 4: 35–38.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shin Matsuoka.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Matsuoka, S., Uchiyama, K., Shima, H. et al. Positivity of extrapulmonary Ga-67 uptake in sarcoidosis: Thyroid uptake due to chronic thyroiditis and bone uptake due to fibrous dysplasia. Ann Nucl Med 15, 537–539 (2001). https://doi.org/10.1007/BF02988509

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02988509

Key words

Navigation