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Anti-estrogenic activity of lignans fromAcanthopanax chiisanensis root

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Abstract

Anti-estrogenic activity of (-)-sesamin (1), helioxanthin (2), savinin (3), taiwanin C (4), and 3-(3,4-dimethoxybenzyl)-2-(3,4-methylenedioxybenzyl)butyrolactone (5) isolated from the root of Acanthopanax chiisanensis was tested using Ishikawa cells. Among them, compound 3 exhibited anti-estrogenic activity (IC50 = 4.86 μM).

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Correspondence to Sanghyun Lee.

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Lee, S., Yoo, H.H., Piao, X.L. et al. Anti-estrogenic activity of lignans fromAcanthopanax chiisanensis root. Arch Pharm Res 28, 186–189 (2005). https://doi.org/10.1007/BF02977713

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  • DOI: https://doi.org/10.1007/BF02977713

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