Abstract
A series of 8-alkyl- and 8-aryl-8,9-dihydro-7H-isoindolo[5,6-g]quinoxaline-7,9-diones were synthesized using sultine chemistry as a key step in good yield. These compounds were evaluated for theirin vitro cytotoxicity against six human cancer cell lines (HCT15, SK-OV-3, A549, SNB19, MCF7 and MCF7/ADR).
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Jung, JK., Jung, EK., Nam-Goong, K. et al. Synthesis and cytotoxic activities of 8-alkyl or 8-aryl-8,9-dihydro-7H-isoindolo[5,6-g]quinoxaline-7,9-diones. Arch Pharm Res 29, 276–281 (2006). https://doi.org/10.1007/BF02968570
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DOI: https://doi.org/10.1007/BF02968570