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D-penicillamine in the treatment of Indian childhood cirrhosis—a preliminary report

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Abstract

A longitudinal study was carried out for evaluating the effect of D-penicillamine in the treatment of 85 biopsy proven cases of Indian childhood cirrhosis. The drug significantly (P< 0.002) reduced the serum and hepatic copper content and simultaneously there was improvement in clinical and symptomatic aspects. This therapy was compared with the conventional corticosteroid therapy. The D-penicillamine therapy was found to be superior (P< 0.002).

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Authors and Affiliations

  1. Department of Pediatrics, Sir Padampat MCH Institute, SMS Medical College, 302 004, Jaipur

    B. S. Tomar M.D. (Lecturer), S. Saxena M.D., P. Prakash M.D., S. Tomar M.B.B.S. & C. Verma M.B.B.S.

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  1. B. S. Tomar M.D.
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  2. S. Saxena M.D.
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  3. P. Prakash M.D.
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  4. S. Tomar M.B.B.S.
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  5. C. Verma M.B.B.S.
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Tomar, B.S., Saxena, S., Prakash, P. et al. D-penicillamine in the treatment of Indian childhood cirrhosis—a preliminary report. Indian J Pediat 50, 613–618 (1983). https://doi.org/10.1007/BF02957727

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