Summary
A case of spontaneous rupture of the spleen as a primary manifestation of acute lymphocytic leukaemia is presented. Pathological findings suggest that the splenic rupture in this case was due to infiltration and destruction of the trabecular arteries by leukaemic cells. Splenectomy was carried out successfully and remission subsequently obtained with chemotherapy.
Similar content being viewed by others
References
Hynes, H. E., Silverstein, M. N., Fawcell, K. J. 1964. Spontaneous rupture of the spleen in acute leukaemia. Cancer. 17, 1356–1360.
Hyun, B. H., Varga, C. F., Rubin, R. J. 1972. Spontaneous and pathologic rupture of the spleen. Arch. Surg. 104, 652–657.
James, I., Wilson, A. J. 1945. Spontaneous rupture of the spleen in sarcoidosis. Brit. J. Surg. 33, 280–282.
Johnson, C. S., Rosen, P. J., Sheehan, W. M. 1979. Acute lymphocytic leukaemia manifesting as Splenic Rupture. A.J.C.P. 71(1) 119–120.
Smith, E. B., Custer, R. P. 1946. Rupture of the spleen in infectious mononucleosis: clinico-pathological report of seven cases. Blood. 1, 317–333.
Wells, E. B., Tillman, C. 1946. Rupture of the spleen due to tularaemia: report of case. Ann. Int. Med. 25, 852–859.
Wolfson, I. N., Croce, E. J., Fite, F. K. 1954. Acute leukaemia with rupture of the spleen as the initial symptom. N.E.J.M. 251, 735–737.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McEntee, G.P., Duignan, J.P., Otridge, B.W. et al. Acute lymphocytic leukaemia presenting as spontaneous splenic rupture. I.J.M.S. 153, 284–285 (1984). https://doi.org/10.1007/BF02939903
Issue Date:
DOI: https://doi.org/10.1007/BF02939903