“As I see it, you’re still short one valve.” Norman Shumway
Abstract
Despite nearly four decades of experience, the role of pulmonary valve autotransplantation (Ross procedure) in the treatment of aortic valve disease in adults and children continues to evolve and remains controversial. As the picture of late results has unfolded, alternating waves of enthusiasm and caution have characterized its use and have led to ongoing refinements in indications and operative technique. At present, it is seen as indispensable in the treatment of aortic valve disease in infants and small children (for whom no satisfactory replacement alternative exixts and for whom growth is essential), attractive for adolescents and young adults who wish to avoid anticoagulants because of childbirth and lifestyle considerations, a reasonable option for selected adults who desire biologic solutions with potentially better durability than conventional bioprostheses, and contraindicated for the elderly and those with connective tissue disorders. Young patients with bicuspid aortic valve are the most common potential recipients, but also the most controversial, because of the risk of autograft dilatation. Optimal matching of prosthesis to patient is a clinical challenge for all caretakers involved in the treatment of valvular heart disease; this review provides guidelines to identify those patients who will benefit most from the Ross procedure, and those for whom it is inadvisable.
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References and Recommended Reading
Lower RR, Stofer RC, Shumway NE:A study of pulmonary valve autotransplantation.Surgery 1960,48:1090–1100.
Ross DN:Replacement of aortic and mitral valves with a pulmonary autograft.Lancet 1967,2:956–958.
Westaby S, Bosher C:Landmarks in Cardiac Surgery. Oxford: Isis medical Media; 1997.
Elkins RC, Lane MM, McCue C: Pulmonary autograft reoperation: incidence and management.Ann Thorac Surg 1996,62:450–455.
Elkins RC:Pulmonary autograft: the optimal substitute for the aortic valve? N Engl J Med 1994,330:59–60.
Gula G, Wain WH, Ross DN:Ten years’ experience with pulmonary autograft replacements for aortic valve disease.Ann Thorac Surg 1979,28:392–396.
Ross DN:Replacement of the aortic valve with a pulmonary autograft: the “switch” operation.Ann Thorac Surg 1991,52:1346–1350.
Matsuki O, Okita Y, Almeida RS, et al.:Two decades’ experience with aortic valve replacement with pulmonary autograft.J Thorac Cardiovasc Surg 1988,95:705–711.
Chambers JC, Somerville J, Stone S, Ross DN:Pulmonary autograft procedure for aortic valve disease, long term results of the pioneer series.Circulation 1997,96:2206–2214.
Al-Khaja N, Belboul A, Rashid M, et al.:The influence of age on the durability of Carpentier-Edwards biological valves.Eur J Cardiothorac Surg 1991,5:635–640.
Elkins RC, Knott-Craig CJ, Randolph JD, et al.:Mediumterm follow-up of pulmonary autograft replacement of aortic valves in children.Eur J Cardiothorac Surg 1994,8:379–383.
Elkins RC, Knott-Craig CJ, Ward KE, et al.:Pulmonary autograft in children: realized growth potential.Ann Thorac Surg 1994,57:1387–1394.
Oury JH:The international registry of the Ross procedure: 1996 results.J Heart Valve Dis 1997,6:333–334.
Kouchoukos NT, Davila-Roman VG, Spray TL, et al.:Replacement of the aortic root with a pulmonary autograft in children and young adults with aortic valve disease.N Engl J Med 1994,330:1–6.
Yacoub MH, Klieverik LM, Melina G, et al.:An evaluation of the Ross procedure in adults.J Heart Valve Dis 2006,15:531–539.
Kouchoukos NT, Masetti P, Nickerson NJ, et al.:The Ross procedure: long-term clinical and echocardiographic follow-up.Ann Thorac Surg 2004,78:773–781.
Fedak PW, de Sa MP, Verma S, et al.:Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation.J Thorac Cardiovasc Surg 2003,126:797–806.
Al-Halees Z, Kumar N, Gallo R, et al.:Pulmonary autograft for aortic valve replacement in rheumatic disease: a caveat.Ann Thorac Surg 1995,60:S172-S175.
Oswalt JD, Dewan SJ:Aortic infective endocarditis managed by the Ross procedure.J Heart Valve Dis 1993,2:380–384.
Calhoon JH, Bolton JW:Ross/Konno procedure for critical aortic stenosis in infancy.Ann Thorac Surg 1995,60(6 Suppl):S597-S599.
Oswalt J:Acceptance and versatility of the Ross procedure.Curr Opin Cardiol 1999,14:90–94.
Lansac E, Lim HS, Shomura Y, et al.:Aortic and pulmonary root, are their dynamics similar? Euro J Cardiothoracic Surg 2002,21:268–275.
Notzold A, Droste DW, Hagedorn G, et al.:circulating microemboli in patients after aortic valve replacement with pulmonary autografts and mechanical valve prosthesis.Circulation 1997,96:1843–1846.
Of importance Duebener LF, Sierle U, Erasmi A, et al.:Ross procedure and left ventricular mass regression.Circulation 2005,112(Suppl I):I-415–I-422. Shows superior benefits of hypertrophy regression.
Of major importance Elkins RC:Valve replacement in children/Ross procedure. InMastery of Cardiothoracic Surgery. Edited by Kaiser LR, Kron IL, Spray TL. Lippincott Williams & Wilkins: Philadelphia; 2006. Important update of Elkins’ pediatric experience.
Svensson G, Alijassim O, Svensson SF, et al.:Anatomical mismatch of the pulmonary autograft in the aortic root may be the cause of early aortic insufficiency after the Ross procedure.Eur J Cardiothoracic Surg 2002,21:1049–1054.
Reddy VM, McElhinney DB, Phoon CK, et al.:Geometric mismatch of pulmonary and aortic annuli in children undergoing the Ross procedure: implications for surgical management and autograft valve function.J Thorac Cardiovasc Surg 1998,115:1255–1263.
Elkins RC, Lane MM, McCue C.:Pulmonary autograft reoperation, incidence and management.Ann Thorac Surg 1996,62:450–455.
O’Brien MF, McGiffin DC, Stafford EG, et al.:Allograft aortic valve replacement: long-term comparative clinical analysis of the viable cryopreserved and antibiotic 4 C stored valves.J Card Surg 1991,6:534–543.
Christie GW, Barratt-Boyes BG:Identification of a failure mode of the antibiotic sterilized aortic allograft after 10 years: implications for their long-term survival.J Card Surg 1991,6:462–467.
Bando K, Danielson GK, Schaff HV, et al.:Outcome of pulmonary and aortic homografts for right ventricular outflow tract reconstruction.J Thorac Cardiovasc Surg 1995,109:509–517.
Fedak PWM, Verma S, David TE, et al.:Clinical and pathophysiological implications of a bicuspid aortic valve.Circulation 2002,106:900–904.
Slater M, Shen I, Welke K, et al.:Modification of the Ross Procedure to prevent autograft dilatation.Semin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2005,8:181–184.
Koul B, Al-Rashidi F, Bhat M, et al.:A modified Ross operation to prevent pulmonary autograft dilatation.Eur J Cardiothorac Surg 2007,31:127–128.
Stelzer P, Weinrauch S, Transbaugh RF:Ten years experience with the modified Ross procedure.J Thorac Cardiovasc Surg 1998,115:1091–1100.
Of importance Khambadkone S, Bonhoeffer P:Percutaneous pulmonary valve implantation.Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2006,9:23–28. Demonstrates potential of catheter intervention on right heart valves.
Of importance Jonas RA:The Ross procedure is not the procedure of choice for the teenager requiring aortic valve replacement.Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2005,8:176–180. An excellent debate on the cons of the Ross procedure in adolescents.
Of importance Khwaja S, Nigro JJ, Starnes VA:The Roos procedure is an ideal aortic valve replacement operation for the teen patient.Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2005,8:173–175. An excellent debate on the pros of the Ross procedure in adolescents.
Permut LC, Ricci M, Cohen GA:Surgery for left ventricular outflow tract obstruction in children. InJohns Hopkins Manual of Cardiothoracic Surgery. Edited by Yuh D, Vricella L, Baumgartner W. Columbus: McGraw-Hill; 2006.
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Cameron, D.E., Vricella, L.A. What is the proper place of the ross procedure in our modern armamentarium?. Curr Cardiol Rep 9, 93–98 (2007). https://doi.org/10.1007/BF02938334
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DOI: https://doi.org/10.1007/BF02938334