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Plasma-exchange in immunologically mediated glomerular diseases

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Ricerca in clinica e in laboratorio

Summary

Intensive plasma-exchange, usually combined with steroids and cyclophosphamide, was carried out in 10 patients with rapidly progressive crescentic glomerulonephritis (primary in six and associated with systemic diseases in four), and in 11 adult patients with severe non-crescentic glomerulonephritis associated with systemic lupus erythematosus in four, and with essential mixed cryoglobulinemia in seven. Therapeutic benefit with improvement in renal function, possibly due to the effect of PE, was achieved in 8/10 patients with RPCGN, in 3/4 patients with SLE non-crescentic nephritis and in 6/7 patients with EMC nephritis.

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Authors and Affiliations

  1. Divisione di Nefrologia e Dialisi, Ospedale San Carlo Borromeo, Via Pio II 3, 20153, Milano, Italia

    Giuseppe D'Amico, Renato Sinico, Alessandro Fornasieri, Franco Ferrario & Giuliano Colasanti

  2. Servizio di Immunoematologia, Ospedale San Carlo Borromeo, Milano, Italia

    Maria Luisa Paracchini & Gian Francesco Fiorini

Authors
  1. Giuseppe D'Amico
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  2. Renato Sinico
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  3. Alessandro Fornasieri
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  4. Franco Ferrario
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  5. Giuliano Colasanti
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  6. Maria Luisa Paracchini
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  7. Gian Francesco Fiorini
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Additional information

This work was supported by grant CT 81.00034.04 from theConsiglio Nazionale delle Ricerche (CNR), Roma, Italy.

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D'Amico, G., Sinico, R., Fornasieri, A. et al. Plasma-exchange in immunologically mediated glomerular diseases. La Ricerca Clin. Lab. 13, 141–157 (1983). https://doi.org/10.1007/BF02904754

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