Skip to main content
SpringerLink
Log in

Study on relationship between anticardiolipin antibody and cerebrovascular diseases

  • Published:
Journal of Tongji Medical University Aims and scope Submit manuscript

Summary

Serum anticardiolipin antibody (ACA) was measured in 91 patients with cerebral infarction (CI), 42 patients with cerebral hemorrhage (CH) and 30 healthy controls. The results showed that the ACA in CI and CH patients was significantly higher than in controls and IgG-ACA was the most important iso-type. Stroke in ACA positive group tended to be recurrent and of multi-focuses. Positive rate of IgG-ACA reached its peak within the first week after stroke on-set. The results suggested that ACA was an independent risk factor in CI and CH and might be valuable in stroke prediction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Montalban J, Rio J, Khamastha Met al. Value of immunologic testing in stroke patients. A prospective multicentre study. Stroke, 1994, 25:2412

    CAS  Google Scholar 

  2. ENA 1997, 10:18

  3. 1997, 5:331

  4. Brey R L, Coull B M. Antiphospholipid antibodies: origin, specificity and mechanism of action. Stroke, 1992, 23(Suppl 1):15

    Google Scholar 

  5. Levine S R, Brey R L, Sawaya K Let al. Recurrent stroke and thrombo-occlusive event in the antiphospholipid syndrome. Ann Neurol, 1995, 38:119

    Article  PubMed  CAS  Google Scholar 

  6. Provenzale J M, Barboriak D P, Allen N Bet al. Patients with antiphospholipid antibodies: CT and MR findings of the brain. AJR, 1996, 167:1573

    PubMed  CAS  Google Scholar 

  7. Muir K W, Squire I B, Alwan Wet al. ACA in an unselected stroke population. Lancet, 1994, 344:452

    Article  PubMed  CAS  Google Scholar 

  8. Kushner M J. Prospective study of anticardiolipin antibodies in stroke. Stroke, 1990, 21: 295

    PubMed  CAS  Google Scholar 

  9. APASS Group. Anticardiolipin antibodies are independent risk factor for first ischemic stroke. Neurology, 1993, 43:2069

    Google Scholar 

  10. Camerlingo M, Casto L, Censori Bet al. Anticardiolipin antibodies in acute nonhemorrhagic stroke seen within six hours after stroke onset. Acta Neurol Scand, 1995, 92:69

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, Xiehe Hospital, Tongji Medical University, Wuhan 430022

    Liu Changqin (Associate Professor), Xia Yun, Sun Shenggang, Yuan Guanglei & Tong E’tang

Authors
  1. Liu Changqin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xia Yun
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sun Shenggang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yuan Guanglei
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Tong E’tang
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Changqin, L., Yun, X., Shenggang, S. et al. Study on relationship between anticardiolipin antibody and cerebrovascular diseases. Journal of Tongji Medical University 19, 59–62 (1999). https://doi.org/10.1007/BF02895599

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02895599

Key words

Search

Navigation