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Correlative factors of left ventricular hypertrophy in end-stage renal disease

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Summary

The correlative factors of left ventricular hypertrophy (LVH) in 287 endstage renal disease (ESRD), admitted from 1983 to 1992, were analyzed. 52% of patients had LVH including 54 % of patients on hemodialysis, 75 % of patients with peritoneal dialysis and 38 % of transplanted patients. Single factor analysis indicated that age, blood pressure, serum creatinine and BUN, hemoglobin, serum alkaline phosphatase, aortic valve disease and present DSRD therapy were related to LVH. Multiple logistic regression analysis indicated that the most important factors which independently related to LVH in all patients studied, were management of present ESRD treatment, age, hypertension and high serum alkaline phosphatase. In a subset of patients with severe LVH, high serum alkaline phosphatase level, high systolic blood pressure and age were the predictive factors. In patients on dialysis, the most important variable were age and high serum alkaline phosphatase. Hypertension was the sole predictor of LVH in the transplant group.

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References

  1. Ma K W, Greene E L, Raij L. Cardiovascular risk factors in chronic renal failure and hemodialysis populations. Am J Kidney Dis, 1992;19(6):505

    PubMed  CAS  Google Scholar 

  2. Rostand S G, Brunzel J D, Cannon R Oet al. Cardiovascular complications in renal failure. J Am Soc Nephrol, 1991;2(6):1053

    PubMed  CAS  Google Scholar 

  3. Deligiannis A, Paschalidou E, Sakellariou Get al. Changes in left ventricular anatomy during hemodialysis, continuous ambulatory peritoneal dialysis and after renal transplantation. Proc Eur Dial Transplant Ass, 1985;21:185

    CAS  Google Scholar 

  4. Salinas C A, Ulloa F, Hermosillo J Aet al. Change in the mass and function of the left ventricle after renal transplantation. Arch Inst Cardiol Mex, 1991;61:527

    Google Scholar 

  5. Nail R B, Gosling P, Price Cet al. Comparative study of alkaline phosphatase isoenzymes, bone histology, and skeletal radiography in dialysis bone disease. Br Med J, 1977;I: 1307

    Google Scholar 

  6. McGoingle R J, Fowler M B, Timmis A Bet al. Uremic cardiomyopathy: potential role of vitamine D and parathyroid hormone. Nephron, 1984;36:94

    Article  Google Scholar 

  7. de Wardener H E, MacGregor G A. The relation of a circulating sodium transport inhibitor to hypertension. Medicine, 1983;62:310

    Article  PubMed  Google Scholar 

  8. Fraser C L, Sarnachi P, Atieff A Iet al. Effects of parathyroid hormone in uremia on calcium transport in rat brain synaptosmoes. Kidney Int, 1986;29:159

    Google Scholar 

  9. Iseki K, Massry S G, Campese WM. Hypercalcemia and hypertension: role of parathyroid hormone. Kidney Int, 1986;29:248

    Google Scholar 

  10. Rambausck M, Ritz E, Mahis Oet al. Myocardial hypertrophy in rats with renal insufficiency. Kidney Int, 1985, 28:775

    Article  Google Scholar 

  11. Ren J F, Hakki A H, Kotler M Net al. Exercise systolic blood pressure: a powerful determinant of increased left ventricular mass in patients with hypertension. J Am Coll Cardiiol, 1985;5:1224

    Article  CAS  Google Scholar 

  12. Gardin J M, Matin K, White Det al. Effect of aging on peak systolic well stress in normal subjects. Clin Res, 1985;33:7

    Google Scholar 

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Yong, D., Shi-jiao, H., Ying, Y. et al. Correlative factors of left ventricular hypertrophy in end-stage renal disease. Journal of Tongji Medical University 13, 252–256 (1993). https://doi.org/10.1007/BF02888021

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