Skip to main content
Log in

Denatured proteins are degraded more rapidly than abnormal proteins in cell-free extracts ofSaccharomyces cerevisiae

  • Brief Report
  • Published:
Folia Microbiologica Aims and scope Submit manuscript

Abstract

Abnormal proteins synthesized in the presence of ethionine were degraded more rapidly than the normal ones in cell-free extracts of ethanol-grown yeast. The denatured proteins, however, were degraded in preference to their native counterparts which were either normal or abnormal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Chaloupka J., Strnadová M.: Kinetics of protein turnover in growing cells ofBacillus megaterium J. Gen. Microbiol. 128, 1003 (1982).

    CAS  Google Scholar 

  • Chaloupka J., Strnadová M., Zalabák V.: Intracellular proteolytic activity during sporulation ofBacillus megaterium.Folia Microbiol. 22, 1 (1977).

    Article  CAS  Google Scholar 

  • Goldberg A.L., Kowit J.D., Etlinger J.D.: Studies of the selectivity and mechanisms of intracellular protein degradation.Miami Winter Symp. 11, 313 (1976).

    CAS  Google Scholar 

  • Goldberg A.L., St. John A.: Intracellular protein degradation in mammalian and bacterial cells: part 2.Ann. Rev. Biochem. 45, 747 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Holzer H., Betz H., Ebner E.: Itracellular proteinases in microorganisms.Current Topics Cellul. Regulation 9, 103 (1975).

    CAS  Google Scholar 

  • Kemshead J.T., Hipkiss A.R.: Degradation of abnormal proteins inEscherichia coli: Relative susceptibility of canavanyl proteins and puromycin peptides to proteolysisin vitro.Eur. J. Biochem. 45, 535 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Klemes Y., Etlinger J.D., Goldberg A.L.: Properties of abnormal proteins degraded rapidly in reticulocytes. Intracellular aggregation of the globin molecules prior to hydrolysis.J. Biol. Chem. 256, 8436 (1981).

    PubMed  CAS  Google Scholar 

  • Liu C.-J., Chopra A.K., Strnadová M., Chaloupka J.: Degradation of abnormal proteins in growing yeast.FEMS Microbiol. Lett. 21, 313 (1984).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Participant of the UNESCO course “On Modern Problems in Biology and Microbial Technology”.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chopra, A.K., Chaloupka, J. Denatured proteins are degraded more rapidly than abnormal proteins in cell-free extracts ofSaccharomyces cerevisiae . Folia Microbiol 29, 343–345 (1984). https://doi.org/10.1007/BF02875968

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02875968

Keywords

Navigation