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Detection of anti-Candida antibodies in neonates from a neonatal intensive care unit

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Abstract

Anti-Candida antibodies were determined in a group of preterm neonates from a neonatal intensive care unit with serious diseases including candidemia. Antibodies toC. albicans blastospores,i.e. antibodies toC. albicans surface mannan and toC. albicans germ tubes were detected. Higher titers of antibodies to blastospores (1:320) occurred in all patients examined while antibodies toC. albicans germ tubes (with the highest titer of 1:160) were present in 32 out of 66 neonates examined. The highest titers of both anti-C. albicans blastospore antibodies and anti-C. albicans germ tube antibodies were detected in neonates with candidemia and disorders of saccharide metabolism.

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Authors and Affiliations

  1. Department of Physiology, Faculty of Medicine, Šafárik University, 040 66, Košice, Slovakia

    E. Dorko

  2. Neonatal Intensive Care Unit, Hospital Šaca, 040 15, Košice, Slovakia

    S. Virágová

  3. Department of Microbiology and Immunology, University of Veterinary Medicine, 041 81, Košice, Slovakia

    E. Pilipčinec & L'. Tkáčiková

Authors
  1. E. Dorko
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  2. S. Virágová
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  3. E. Pilipčinec
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  4. L'. Tkáčiková
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Dorko, E., Virágová, S., Pilipčinec, E. et al. Detection of anti-Candida antibodies in neonates from a neonatal intensive care unit. Folia Microbiol 47, 297–301 (2002). https://doi.org/10.1007/BF02817656

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  • DOI: https://doi.org/10.1007/BF02817656

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