Abstract
Cystic fibrosis, the most common congenital lethal disease of western Caucasian population is usually diagnosed by the finding of Na+ or Cl- levels of more than 60mEq/L in sweat. Pilocarpine iontophoresis was done to collect sweat; conductivity of sweat is extrapolated in the standard graph to find out concentration and this was compared with the standard method i.e. flame photometry. 19 patients of chronic chest disease were studied and one patient was detected to be havihg cystic fibrosis.
Similar content being viewed by others
References
Nelson Weldo E. Sweat test by pilocarpine iontophoresis.Textbook of pediatrics, Eleventh edition. WB Saunders Company, p. 1996
Agnsse, D’sant AP Davis, PB. Medical progress: Research in cystic fibrosis (in three parts).New Engl J Med 1976;295 : 481–485, 534–541, 597–602
Agness, D’Sant PA, Darling, RC, Perera GA, et al. Abnormal electrolyte composition of sweat in Cystic Fibrosis of pancrease.Pediatrics 1953;12: 549–563
Cotlove, E. Chloride in standard methods of clinical chemistry, Vol. 3, edited by D. ’Selgson, New York; Academic Press, 1961, p 81
Bauer, John D. Sodium and potassium: Determination by flame photometry. Clinical Laboratory Methods—9th Edition. The C.V. Mosby Company, St. Louis Joronto, London 1982, p 519–521
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sharma, A.K., Chetty, A. Diagnosis of cystic fibrosis by conductometry. Indian J Pediatr 55, 431–435 (1988). https://doi.org/10.1007/BF02810369
Issue Date:
DOI: https://doi.org/10.1007/BF02810369